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Concept

Catechol-O-methyltransferase

Publications associées (5)

Dopamine Dynamics in Reward-based Learning

Jun Huang

Dopamine signals are thought to be important for reward-based learning and appear to play important roles in regulating synaptic plasticity in the nucleus accumbens and the striatum. However, the precise neuronal circuit mechanisms underlying the learning ...

EPFL2022

Lack of Enantioselectivity in the SULT1A3-catalyzed Sulfoconjugation of Normetanephrine Enantiomers: An In Vitro and Computational Study

Sandrine Gerber, Jean-Baptiste Gualtierotti

(1R)-Normetanephrine is the natural stereoisomeric substrate for sulfotransferase 1A3 (SULT1A3)-catalyzed sulfonation. Nothing appears known on the enantioselectivity of the reaction despite its potential significance in the metabolism of adrenergic amines ...

Wiley-Blackwell2013

Microengineered analytical tools for cell-based studies in environmental monitoring, pharmacology and neuroscience

Sara Talaei

Monitoring cells’ Tehavior in-vitro and evaluation of their response to different types of stimulations are the major oTjectives in cell-Tased studies. The results of these studies answer questions on the physiology of the cells, cell-to-cell signaling and ...

EPFL2013

Synthetic calibrators for the analysis of sulfoconjugated metanephrines in urine: hydrolysis conditions revisited

Sandrine Gerber, Jonathan Simonin

Background: The quantification of total (free + sulfated) metanephrines in urine is recommended to diagnose pheochromocytoma. Urinary metanephrines include metanephrine itself, normetanephrine and methoxytyramine, mainly in the form of sulfate conjugates ( ...

Elsevier2012

Genes, Brain Development and Psychiatric Phenotypes in Velo-Cardio-Facial Syndrome

Marie Schaer

Velo-cardio-facial syndrome (VCFS) has been in the focus of intensive research over the last 15 years. The syndrome represents a homogeneous model for studying the effect of a decreased dosage of genes on the development of brain structure and function and ...

2008