Concept

Adverse childhood experiences

Publications associées (27)

Social deficits induced by peripubertal stress in rats are reversed by resveratrol

Maria del Carmen Sandi Perez, Olivia Zanoletti, Guillaume Poirier

Adolescence is increasingly recognized as a critical period for the development of the social system, through the maturation of social competences and of their underlying neural circuitries. The present study sought to test the utility of resveratrol, a di ...

2014

Pansynaptic Enlargement at Adult Cortical Connections Strengthened by Experience

Graham Knott

Behavioral experience alters the strength of neuronal connections in adult neocortex. These changes in synaptic strength are thought to be central to experience-dependent plasticity, learning, and memory. However, it is not known how changes in synaptic tr ...

Oxford University Press2014

Role of the HPA axis in the long-term programming of social behaviors by peripuberty stress : behavioral, pharmacological and molecular approaches

Vandana Veenit

Stress during childhood and adolescence enhances the risk of psychopathology later in life. In fact, exposure to stress during this period is known to predispose individuals to the development of psychopathologies such as depression and anxiety disorders l ...

EPFL2013

Peripuberty stress leads to abnormal aggression, altered amygdala and orbitofrontal reactivity and increased prefrontal MAOA gene expression

Pierre Magistretti, Maria del Carmen Sandi Perez, Didier Trono, Maria Isabel Cordero Campana, Guillaume Poirier, Anna Claire Groner

Although adverse early life experiences have been found to increase lifetime risk to develop violent behaviors, the neurobiological mechanisms underlying these long-term effects remain unclear. We present a novel animal model for pathological aggression in ...

Nature Publishing Group2013

Distinct illusory own-body perceptions caused by damage to posterior insula and extrastriate cortex

Olaf Blanke, Lukas Heydrich

Recent research in cognitive neuroscience using virtual reality, robotic technology and brain imaging has linked self-consciousness to the processing and integration of multisensory bodily signals. This work on bodily self-consciousness has implicated the ...

2013

Evidence for biological roots in the transgenerational transmission of intimate partner violence

Maria del Carmen Sandi Perez, Maria Isabel Cordero Campana, Guillaume Poirier, Vandana Veenit, Basira Salehi

Intimate partner violence is a ubiquitous and devastating phenomenon for which effective interventions and a clear etiological understanding are still lacking. A major risk factor for violence perpetration is childhood exposure to violence, prompting the p ...

2012

The intense world theory - a unifying theory of the neurobiology of autism

Henry Markram, Kamila Markram

Autism covers a wide spectrum of disorders for which there are many views, hypotheses and theories. Here we propose a unifying theory of autism, the Intense World Theory. The proposed neuropathology is hyper-functioning of local neural microcircuits, best ...

2010