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Concept

Syndrome douloureux régional complexe

Publications associées (12)

Development and clinical validation of computational imaging biomarkers for neurodegenerative diseases

Veronica Lily Ravano

Neurodegenerative and neuroinflammatory disorders often involve complex pathophysiological mechanisms that are â to this date â only partially understood. A more comprehensive understanding of those microstructural processes and their characterization ...

EPFL2024

Sensory-Motor Neurostimulation to Enhance Exosuit Performance

Silvestro Micera, Stanisa Raspopovic, Giacomo Valle, Andrea Crema

Exosuits typically provide limited mechanical support and rely on a user's residual functional ability. However, people with neurological impairments often suffer from both motor and sensory deficits that limit the assistance an exosuit can provide. To ove ...

IEEE2023

Longitudinal interrogation of sympathetic neural circuits and hemodynamics in preclinical models

Grégoire Courtine, Quentin Barraud, Jordan Squair, Matthieu Pierre Gautier, Loïs Thomas Romain Mahe, Rémi Bernard René Hudelle, Suje Amir, Victor Perez Puchalt, Jan Elaine Cuevas Soriano

Neurological disorders, including spinal cord injury, result in hemodynamic instability due to the disruption of supraspinal projections to the sympathetic circuits located in the spinal cord. We recently developed a preclinical model that allows the ident ...

NATURE PORTFOLIO2022

During capsaicin-induced central sensitization, brush allodynia is associated with baseline warmth sensitivity, whereas mechanical hyperalgesia is associated with painful mechanical sensibility, anxiety and somatization

Anne-Christine Schmid

Background Mechanical hyperalgesia and allodynia incidence varies considerably amongst neuropathic pain patients. This study explored whether sensory or psychological factors associate with mechanical hyperalgesia and brush allodynia in a human experimenta ...

WILEY2021

Predicting task performance from biomarkers of mental fatigue in global brain activity

Mahsa Shoaran

Objective. Detection and early prediction of mental fatigue (i.e. shifts in vigilance), could be used to adapt neuromodulation strategies to effectively treat patients suffering from brain injury and other indications with prominent chronic mental fatigue. ...

IOP PUBLISHING LTD2021

Enhancing analgesic spinal cord stimulation for chronic pain with personalized immersive virtual reality

Olaf Blanke, Bruno Herbelin, Andrea Serino, Giulio Rognini, Marco Solcà, Robin Mange, Pavo Orepic

Spinal cord stimulation (SCS) is an approved treatment for truncal and limb neuropathic pain. However, pain relief is often suboptimal and SCS efficacy may reduce over time, requiring sometimes the addition of other pain therapies, stimulator revision, or ...

2021

Behavioral and neurophysiological evidence for altered interoceptive bodily processing in chronic pain

Olaf Blanke, Fosco Bernasconi, Marco Solcà, Hyeongdong Park

Whereas impaired multisensory processing of bodily stimuli and distorted body representation are well-established in various chronic pain disorders, such research has focused on exteroceptive bodily cues and neglected bodily signals from the inside of the ...

2020

Cognitive neuroprosthetics for investigating and restoring body perception

Marco Solcà

Our brain constantly receives and integrates a flow of multisensory bodily inputs that are responsible for the way our body is represented and consciously experienced. However, in some pathological conditions, patients might experience altered perceptions ...

EPFL2019

Heartbeat-enhanced immersive virtual reality to treat complex regional pain syndrome

Olaf Blanke, Bruno Herbelin, Andrea Serino, Roberta Ronchi, Javier Bello Ruiz, Marco Solcà, Thomas Schmidlin

OBJECTIVES: To develop and test a new immersive digital technology for complex regional pain syndrome (CRPS) that combines principles from mirror therapy and immersive virtual reality and the latest research from multisensory body processing. METHODS: In t ...

2018

Quantifying dimensions of physical behavior in chronic pain conditions

Kamiar Aminian, Anisoara Ionescu

Background: Chronic pain, defined as persistent or recurrent pain lasting longer than 3 months, is a frequent condition affecting an important percent of population worldwide. Pain chronicity can be caused by many different factors and is a frequent compon ...

BioMed Central2016

Size and Viewpoint of an Embodied Virtual Body Affect the Processing of Painful Stimuli

Olaf Blanke, Joan Llobera Mahy

Looking at one's own body might induce visual analgesia. However, the cognitive and physiological mechanisms underlying such visual analgesia are unknown. Because body and pain representations in the brain are multisensory, and have been reported to partia ...

Churchill Livingstone2015

A two-arm coordination model for phantom limb pain rehabilitation

Ronan Boulic, Eray Molla

Following limb loss, patients usually continue having sensations on their missing limbs as if they were still present. Signicant amount of such sensations are painful and referred as Phantom Limb Pain (PLP). Previous research has shown that providing the p ...

ACM Press2013