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Concept

Local field potential

Publications associées (30)

Semi-automatic 3D morphological reconstruction of neurons with densely branching morphology: Application to retinal All amacrine cells imaged with multi -photon excitation microscopy

Bas-Jan Zandt

Background: Accurate reconstruction of the morphology of single neurons is important for morphometric studies and for developing compartmental models. However, manual morphological reconstruction can be extremely time-consuming and error-prone and algorith ...

Elsevier2017

Effect of Ionic Diffusion on Extracellular Potentials in Neural Tissue

Daniel Keller

Recorded potentials in the extracellular space (ECS) of the brain is a standard measure of population activity in neural tissue. Computational models that simulate the relationship between the ECS potential and its underlying neurophysiological processes a ...

Public Library of Science2016

Movement Initiation Signals in Mouse Whisker Motor Cortex

Carl Petersen, Sylvain Crochet, Katia Galan, Varun Sreenivasan, Vahid Esmaeili, Taro Kiritani

Frontal cortex plays a central role in the control of voluntary movements, which are typically guided by sensory input. Here, we investigate the function of mouse whisker primary motor cortex (wM1), a frontal region defined by dense innervation from whiske ...

Cell Press2016

Target-specific membrane potential dynamics of neocortical projection neurons during goal-directed behavior

Carl Petersen, Takayuki Yamashita

Goal-directed behavior involves distributed neuronal circuits in the mammalian brain, including diverse regions of neocortex. However, the cellular basis of long-range cortico-cortical signaling during goal-directed behavior is poorly understood. Here, we ...

Elife Sciences Publications Ltd2016

Comments and General Discussion on “The Anatomical Problem Posed by Brain Complexity and Size: A Potential Solution”

Sean Lewis Hill, Idan Segev

This article gathers together different opinions on the current status and future directions of the study of the brain, taking as a working document the article “The anatomical problem posed by brain complexity and size: a potential solution” http://journa ...

Frontiers Research Foundation2016

Tight Coupling of Astrocyte pH Dynamics to Epileptiform Activity Revealed by Genetically Encoded pH Sensors

Henry Markram

Astrocytes can both sense and shape the evolution of neuronal network activity and are known to possess unique ion regulatory mechanisms. Here we explore the relationship between astrocytic intracellular pH dynamics and the synchronous network activity tha ...

Soc Neuroscience2016

Cell-type- and activity-dependent extracellular correlates of intracellular spiking

Henry Markram, Rodrigo de Campos Perin, Constantinos Anastassiou

Despite decades of extracellular action potential (EAP) recordings monitoring brain activity, the biophysical origin and inherent variability of these signals remains enigmatic. We performed whole-cell patch recordings of excitatory and inhibitory neurons ...

2015

Duration of Purkinje cell complex spikes increases with their firing frequency

Michele Giugliano

Climbing fiber (CF) triggered complex spikes (CS) are massive depolarization bursts in the cerebellar Purkinje cell (PC), showing several high frequency spikelet components (+/- 600 Hz). Since its early observations, the CS is known to vary in shape. In th ...

Frontiers Research Foundation2015

Cell-Type-Specific Sensorimotor Processing in Striatal Projection Neurons during Goal-Directed Behavior

Carl Petersen, Sylvain Crochet, Tanya C Sippy, Damien Lapray

Goal-directed sensorimotor transformation drives important aspects of mammalian behavior. The striatum is thought to play a key role in reward-based learning and action selection, receiving glutamatergic sensorimotor signals and dopaminergic reward signals ...

Cell Press2015

Whisking-Related Changes in Neuronal Firing and Membrane Potential Dynamics in the Somatosensory Thalamus of Awake Mice

Carl Petersen

The thalamus transmits sensory information to the neocortex and receives neocortical, subcortical, and neuromodulatory inputs. Despite its obvious importance, surprisingly little is known about thalamic function in awake animals. Here, using intracellular ...

Elsevier2015