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Concept

Developmental language disorder

Publications associées (21)

Novel Methods For Detection And Analysis Of Atypical Aspects In Speech

Julian David Fritsch

Atypical aspects in speech concern speech that deviates from what is commonly considered normal or healthy. In this thesis, we propose novel methods for detection and analysis of these aspects, e.g. to monitor the temporary state of a speaker, diseases tha ...

EPFL2023

Kinesthetic motor-imagery training improves performance on lexical-semantic access

Sylvain Jean-François Harquel

The objective of this study was to evaluate the effect of Motor Imagery (MI) training on language comprehension. In line with literature suggesting an intimate relationship between the language and the motor system, we proposed that a MI-training could imp ...

PUBLIC LIBRARY SCIENCE2022

“It Is Not the Robot Who Learns, It Is Me.” Treating Severe Dysgraphia Using Child–Robot Interaction

Pierre Dillenbourg, Wafa Monia Benkaouar Johal, Thibault Lucien Christian Asselborn, David Cohen

Writing disorders are frequent and impairing. However, social robots may help to improve children's motivation and to propose enjoyable and tailored activities. Here, we have used the Co-writer scenario in which a child is asked to teach a robot how to wri ...

2021

Structural control energy of resting-state functional brain states reveals less cost-effective brain dynamics in psychosis vulnerability

Dimitri Nestor Alice Van De Ville, Marie Schaer

How the brain's white-matter anatomy constrains brain activity is an open question that might give insights into the mechanisms that underlie mental disorders such as schizophrenia. Chromosome 22q11.2 deletion syndrome (22q11DS) is a neurodevelopmental dis ...

Wiley2021

White matter hyperintensities at critical crossroads for executive function and verbal abilities in small vessel disease

Nathalie Heidi Meyer

The presence of white matter lesions in patients with cerebral small vessel disease (SVD) is among the main causes of cognitive decline. We investigated the relation between white matter hyperintensity (WMH) locations and executive and language abilities i ...

Wiley2021

Identifying neurodevelopmental anomalies of white matter microstructure associated with high risk for psychosis in 22q11.2DS

Marie Schaer, Maude Schneider, Daniela Maria Zöller

Disruptions of white matter microstructure have been widely reported in schizophrenia. However, the emergence of these alterations during preclinical stages remains poorly understood. 22q11.2 Deletion Syndrome (22q11.2DS) represents a unique model to study ...

SPRINGERNATURE2020

Tapping into Multi-Faceted Human Behavior and Psychopathology Using fMRI Brain Dynamics

Dimitri Nestor Alice Van De Ville, Maria Giulia Preti, Thomas William Arthur Bolton, Elenor Morgenroth

Human behavior comprises many aspects that stand out by their dynamic nature. To quantify its neural underpinnings, time-resolved fMRI methods have blossomed over the past decade. In this review we conceptually organize a broad repertoire of dynamic analyt ...

2020

Automated human-level diagnosis of dysgraphia using a consumer tablet

Pierre Dillenbourg, Wafa Monia Benkaouar Johal, Thibault Lucien Christian Asselborn, Lukasz Kidzinski, David Cohen

The academic and behavioral progress of children is associated with the timely development of reading and writing skills. Dysgraphia, characterized as a handwriting learning disability, is usually associated with dyslexia, developmental coordination disord ...

Springer2018

Effects of Binaural Spatialization in Wireless Microphone Systems for Hearing Aids on Normal-Hearing and Hearing-Impaired Listeners

Hervé Lissek, Xavier Gigandet, Gilles André Courtois

Little is known about the perception of artificial spatial hearing by hearing-impaired subjects. The purpose of this study was to investigate how listeners with hearing disorders perceived the effect of a spatialization feature designed for wireless microp ...

2018

The Number of Genomic Copies at the 16p11.2 Locus Modulates Language, Verbal Memory, and Inhibition

Nouchine Hadjikhani, Borja Rodriguez Herreros, Loyse Hippolyte

BACKGROUND: Deletions and duplications of the 16p11.2 BP4-BP5 locus are prevalent copy number variations (CNVs), highly associated with autism spectrum disorder and schizophrenia. Beyond language and global cognition, neuropsychological assessments of thes ...

Elsevier Science Inc2016

A Wearable Camera Detects Gaze Peculiarities during Social Interactions in Young Children with Pervasive Developmental Disorders

Aude Billard, Patrick Jermann, Basilio Noris, Silvia Magrelli

We report on the study of gazes, conducted on children with pervasive developmental disorders (PDD), by using a novel head-mounted eye-tracking device called the WearCam. Due to the portable nature of the WearCam, we are able to monitor naturalistic intera ...

Ieee-Inst Electrical Electronics Engineers Inc2014

Hyper-emotional neurophysiology in a rat model of autism

Mônica Regina Favre

Autism is a pervasive neurodevelopmental disorder of unknown etiology, characterized by a spectrum of symptoms of social impairment, abnormal communication, and unusual restricted, inflexible behaviors. Patients also frequently present various levels of se ...

EPFL2013

General developmental health in the VPA-rat model of autism

Henry Markram, Kamila Markram, Georges Khazen, Mônica Regina Favre

Autism is a neurodevelopmental condition diagnosed by impaired social interaction, abnormal communication and, stereotyped behaviors. While post-mortem and imaging studies have provided good insights into the neurobiological symptomology of autism, animal ...

Frontiers Research Foundation2013

Social orienting of children with autism to facial expressions and speech: a study with a wearable eye-tracker in naturalistic settings

Aude Billard, Patrick Jermann, Basilio Noris, Silvia Magrelli

This study investigates attention orienting to social stimuli in children with Autism Spectrum Conditions (ASC) during dyadic social interactions taking place in real-life settings. We study the effect of social cues that differ in complexity and distingui ...

Frontiers Media2013

Machine Vision-Based Analysis of Gaze and Visual Context : an Application to Visual Behavior of Children with Autism Spectrum Disorders

Basilio Noris

Visual behavior, and specifically gaze directed at objects and people, is a fundamental cue for understanding how children with Autism Spectrum Disorder (ASD) experience and respond to social interaction. Indeed atypical behaviors such as averting the gaze ...

EPFL2011

Analysis of pathologies and long term behaviour of the Swiss national road tunnels

Federica Sandrone

This project, supported by the Swiss Federal Roads Authority (OFROU), focuses on the long term behaviour of road tunnels and on their main pathologies. As a tunnel is composed by lining structure and rock mass, it has been necessary to consider the effects ...

EPFL2008

Methods For Treating And/Or Preventing Pervasive Developmental Disorders In A Subject

Henry Markram, Tania Rinaldi, Karina Kulangara

The present invention concerns a method for treating and/or preventing a Pervasive Developmental Disorder in a subject in need thereof comprising the step of modulating the synaptic connectivity in the neocortex by administering a therapeutically effective ...

2007

WearCam: A head mounted wireless camera for monitoring gaze attention and for the diagnosis of developmental disorders in young children

Aude Billard, Basilio Noris

Autism covers a large spectrum of disorders that affect the individual’s way of interacting socially and is often revealed by the individual’s lack of interest in gazing at human faces. Currently Autism is diagnosed in children no younger than 2 years old. ...

2007

Speech arrest with stimulation may not reliably predict language deficit after epilepsy surgery

Olaf Blanke

The authors present a patient in whom electrical cortical stimulation of the posterior temporal cortex induced speech arrest, comprehension deficits, and other language-related impairments. This area was ultimately resected because of persistence of a seve ...

American Academy of Neurology2006

Altered neocortical microcircuitry in the valproic acid rat model of autism

Tania Rinaldi

Autism is a wide-spectrum disorder with early childhood onset, affecting general cognitive capabilities and, in particular, complex information processing. Although interesting directions of research start to appear, the precise causes of the disorder and ...

EPFL2006