Olfaction, the detection of odorous chemicals in the environment, is one of the oldest mammalian sensory systems and involves large number (up to 1000) of distinct G protein coupled olfactory receptors (OR). The chemical interaction of volatile molecules w ...
Odor perception may be considered from different perspectives: the physicochemical properties of odorants and target surfaces of interest, the biological aspects of electing odorant molecules by odorant receptors and their related downstream cellular signa ...
Despite the importance of trafficking for regulating G protein-coupled receptor signaling, for many members of the seven transmembrane helix protein family, such as odorant receptors, little is known about this process in live cells. Here, the complete lif ...