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Concept

Insomnie

Publications associées (14)

Optimized office lighting advances melatonin phase and peripheral heat loss prior bedtime

Jean-Louis Scartezzini, Mirjam Münch, Marta Benedetti, Lenka Maierova

Improving indoor lighting conditions at the workplace has the potential to support proper circadian entrainment of hormonal rhythms, sleep, and well-being. We tested the effects of optimized dynamic daylight and electric lighting on circadian phase of mela ...

Nature Research2022

Contactless Sleep Monitoring for Early Detection of Health Deteriorations in Community-Dwelling Older Adults: Exploratory Study

Daniel Gatica-Perez, Philipp Buluschek

Background: Population aging is posing multiple social and economic challenges to society. One such challenge is the social and economic burden related to increased health care expenditure caused by early institutionalizations. The use of modern pervasive ...

JMIR PUBLICATIONS, INC2021

Sleep-wake-driven and circadian contributions to daily rhythms in gene expression and chromatin accessibility in the murine cortex

Felix Naef, Jake Yeung, Maxime Jan

The timing and duration of sleep results from the interaction between a homeostatic sleep-wake-driven process and a periodic circadian process, and involves changes in gene regulation and expression. Unraveling the contributions of both processes and their ...

National Academy of Sciences2019

Can Daytime Napping Assist the Process of Skills Acquisition After Stroke?

Friedhelm Christoph Hummel, Winifried Backhaus

Acquisition and reacquisition of skills is a main pillar of functional recovery after stroke. Nighttime sleep has a positive influence on motor learning in healthy individuals, whereas the effect of daytime sleep on neuro-rehabilitative training and relear ...

2018

Sleep fragmentation alters brain energy metabolism without modifying hippocampal electrophysiological response to novelty exposure

Pierre Magistretti, Maxime Olivier Baud

Sleep is viewed as a fundamental restorative function of the brain, but its specific role in neural energy budget remains poorly understood. Sleep deprivation dampens brain energy metabolism and impairs cognitive functions. Intriguingly, sleep fragmentatio ...

Wiley-Blackwell2016

On the Impact of Integration of Non-Image Forming (NIF) Effect of Light on Electrical Lighting Control in Non-Residential Buildings

Jean-Louis Scartezzini, Ali Motamed, Marta Benedetti

Lighting has an impact on the visual as well as cognitive performance of people in non-residential buildings. Light is the most powerful time cue for resetting the circadian pacemaker and ensuring correct synchronization of the internal clock with the envi ...

2016

Comparison of acute non-visual bright light responses in patients with optic nerve disease, glaucoma and healthy controls

This study examined the effect of optic nerve disease, hence retinal ganglion cell loss, on nonvisual functions related to melanopsin signalling. Test subjects were patients with bilateral visual loss and optic atrophy from either hereditary optic neuropat ...

Nature Publishing Group2015

Sustained Sleep Fragmentation Induces Sleep Homeostasis in Mice

Pierre Magistretti, Maxime Olivier Baud

Study Objectives: Sleep fragmentation (SF) is an integral feature of sleep apnea and other prevalent sleep disorders. Although the effect of repetitive arousals on cognitive performance is well documented, the effects of long-term SF on electroencephalogra ...

American Academy of Sleep Medicine2015

Dual orexin receptor antagonists - promising agents in the treatment of sleep disorders

Damien Lapray

Insomnia is a serious medical and social problem, its prevalence in the general population ranges from 9 to 35% depending on the country and assessment method. Often, patients are subject to inappropriate and therefore dangerous pharmacotherapies that incl ...

Cambridge Univ Press2014

Fractal temporal organization of motricity is altered in major depression

Kamiar Aminian, Anisoara Ionescu

Objective: Motor changes in major depression (MD) may represent potential markers of treatment response. Physiological rhythms (heart rate/gait cycle/hand movements) have been recently shown to be neither random nor regular but to display a fractal tempora ...

Elsevier2012

SleepPic. Hardware Developments for a Wearable On-line Sleep and Wake Discrimination System

Dario Floreano

The design of wearable systems comes with constraints in computational and power resources. We describe the development of customized hardware for the wearable discrimination of human sleep and wake based on cardio-respiratory signals. The device was desig ...

SciTePress2011

The Impact of Sleep Fragmentation on Sleep Homeostasis, Brain and Peripheral Energy Metabolism and Spatial Learning

Maxime Olivier Baud

The quality of sleep has recently come to the forefront of public health concerns in industrialized nations. Indeed, voluntary sleep curtailment is widespread, sleep disorders are increasingly recognized and both correlate with the current epidemiology of ...

EPFL2011

The antidepressant agomelatine blocks the adverse effects of stress on memory and enables spatial learning to rapidly increase neural cell adhesion molecule (NCAM) expression in the hippocampus of rats

Maria del Carmen Sandi Perez

Agomelatine, a novel antidepressant with established clinical efficacy, acts as a melatonin receptor agonist and 5-HT(2C) receptor antagonist. As stress is a significant risk factor in the development of depression, we sought to determine if chronic agomel ...

Cambridge University Press2009

Sleep improves the variability of motor performance

Sean Lewis Hill

Sleep after learning often enhances task performance, but the underlying mechanisms remain unclear. Using a well-characterized rotation learning paradigm implemented both behaviorally and in computer simulations, we compared two main hypotheses: the first, ...

2008