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Concept

Pilosité humaine

Publications associées (17)

Role of the androgen receptor in the human breast epithelium

Fabio De Martino

Breast cancer is the most common malignancy in women worldwide and understanding the risk factors affecting it is key for prevention. The relative risk of developing breast cancer is related to exposure to both endogenous hormones and exogenous natural and ...

EPFL2022

Characterization of cancer stem cell subpopulations from patient-derived xenografts of advanced prostate cancer

Markus Germann

Androgen-deprivation therapy is the standard treatment for prostate cancer. Despite the initial response, a fraction of cases manifest progression to castration-resistant prostate cancer. PCa recurrence is possibly due to androgen-independent cancer stem c ...

AMER ASSOC CANCER RESEARCH2018

Selective Peptide-Mediated Enhanced Deposition of Polymer Fragrance Delivery Systems on Human Hair

Harm-Anton Klok, Kemal Arda Günay

The deposition of fragrance delivery systems onto human hair from a shampoo formulation is a challenging task, as the primary function of shampoo is to cleanse the hair by removing primarily hydrophobic moieties. In this work, to tackle this challenge, pha ...

2017

Bioinspired Selective Surface Deposition of Fragrance Delivery Systems

Kemal Arda Günay

The perception of pleasantness in many of the consumer goods is provided by volatile chemical compounds called fragrances. While the volatility of fragrances is essential to provide a pleasant olfactory response, it presents at the same time a technologi ...

EPFL2016

Parabolic tailored-potential quantum-wires grown in inverted pyramids

Elyahou Kapon, Alok Rudra, Justyna Szeszko, Mikhail Lazarev

Quasi-one-dimensional AlGaAs quantum wires (QWRs) with parabolic heterostructure profiles along their axis were fabricated using metallorganic vapor phase epitaxy (MOVPE) On patterned (111)B GaAs substrates. Tailoring of the confined electronic states via ...

Elsevier Science Bv2015

Coat color dilution in mice because of inactivation of the melanoma antigen MART-1

Friedrich Beermann, Iraz Toprak Aydin

Melanoma antigen recognized by T cells 1 (MART-1) is a melanoma-specific antigen, which has been thoroughly studied in the context of immunotherapy against malignant melanoma and which is found only in the pigment cell lineage. However, its exact function ...

2012

Constitutive gray hair in Mice induced by Melanocyte-specific deletion of c-Myc

Friedrich Beermann, Marzia Armaro

c-Myc is involved in the control of diverse cellular processes and implicated in the maintenance of different tissues including the neural crest. Here we report that c-Myc is particularly important for pigment cell development and homeostasis. Targeting c- ...

2012

The Role of LEKTI in the Fate Determination of Keratinocyte Stem Cells

Alessandro Wataru Amici

SPINK5 (serine protease inhibitor Kazal-type 5) encodes the proteinase inhibitor LEKTI (lympho-epithelial Kazal-type related inhibitor). In skin, LEKTI expression is restricted to the stratum granulosum of the epidermis and the inner root sheath of hair fo ...

EPFL2011

Dynamic hair capture

Mark Pauly, Hao Li

The realistic reconstruction of hair motion is challenging because of hair’s complex occlusion, lack of a well-defined surface, and non-Lambertian material. We present a system for passive capture of dynamic hair performances using a set of high-speed vide ...

Tech. Rep. Technical Report TR-907-11, Princeton University2011

Key roles for transforming growth factor beta in melanocyte stem cell maintenance

Friedrich Beermann

Melanocyte stem cells in the bulge area of hair follicles are responsible for hair pigmentation, and defects in them cause hair graying. Here we describe the process of melanocyte stem cell entry into the quiescent state and show that niche-derived transfo ...

2010

Target of rapamycin modulators of and use thereof

Yann Barrandon, Fahd Azzabi Zouraq

The present invention is related to new molecules capable of interacting with target of rapamycin (TOR) transcriptional complex. In particular, the present invention provides novel nucleic acid molecules, processes for production thereof, kits containing t ...

2009

Acquisition et recalage informatique d'images confocales de tissus denses : application à l'étude de la papille folliculaire de vibrisse de souris

Analysis of the 3D structure of a biological sample is an important step to model cell and tissue dynamics. As a model system, we set up to determine the number of nuclei in a follicular papilla using confocal imaging and 3D computer reconstruction. The fo ...

EPFL2008

Control of thrombin signaling through PI3K is a mechanism underlying plasticity between hair follicle dermal sheath and papilla cells

Yann Barrandon

In hair follicles, dermal papilla (DP) and dermal sheath (DS) cells exhibit striking levels of plasticity, as each can regenerate both cell types. Here, we show that thrombin induces a phosphoinositide 3-kinase (PI3K)-Akt pathway-dependent acquisition of D ...

Company of Biologists2008

Epithelial stem cells and mechanical signal transduction : a functional unit?

Vincent Bernard Cattin

Hair follicles are cutaneous structures characteristic of mammals. These sensitive organs cycle and contain multipotent epithelial stem cells which are implicated in hair growth and hair cycle. A single whisker follicle of the rat hosts up to 1500 stem cel ...

EPFL2008

Notch1 and Notch2 receptors influence progressive hair graying in a dose-dependent manner

Freddy Radtke, Friedrich Beermann

The Notch signaling pathway is involved in diverse biological processes such as cell fate decisions or stem cell maintenance. In this study, we assessed the role of this pathway for melanocyte development and hair pigmentation using RBP-Jkappa, Notch1, and ...

2007

Model surfaces for human hair : screening perfumes and surfactants

Mabel Maucci

The thesis describes the development of surfaces that model the surface of human hair in order to characterize the adsorption of detergents and perfumes. Three types of model surfaces were investigated consisting of (i) a self-assembled monolayer of protei ...

EPFL2006

Notch1 is essential for postnatal hair follicle development and homeostasis

Freddy Radtke, Yann Barrandon

Notch genes encode evolutionarily conserved large, single transmembrane receptors, which regulate many cell fate decisions and differentiation processes during fetal and postnatal life. Multiple Notch receptors and ligands are expressed in both developing ...

2005