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Concept

Electrical synapse

Publications associées (30)

Nonlinear microscopy for temporally and spatially resolved label-free imaging of living cells

Marie Eve Pascale Didier

The human brain consists of approximately a hundred billion of neurons that communicate through a unique series of biochemical and electrical processes. When neuronal networks are solicited, electrochemical processes happen involving millions of cells with ...

EPFL2018

Intrafascicular electrode implant

Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini

An implantable device for intrafascicular stimulation and/or sensing of a peripheral nerve, including a blocking element adapted for wrapping a nerve, comprising an access point and an exit point, and an electrode adapted to traverse the blocking element v ...

2018

The dopaminergic VTA - basal amygdala projection contributes to signal aversive state in fear memory

Wei Tang

Dopamine released from midbrain neurons is an important neuromodulatory signal during associative learning in many forebrain circuits. One model of associative learning is auditory cued fear learning, during which an innocuous sensory percept like a tone ( ...

EPFL2018

An Efficient Electronic Measurement Interface for Memristive Biosensors

Giovanni De Micheli, Sandro Carrara, Pierre-Emmanuel Julien Marc Gaillardon, Ioulia Tzouvadaki

Reducing sensing time is one major concern in clinical diagnostics. In the present work, a robust measurement system is developed aiming at the faster and easier signal acquisition of memristive biosensors. Sensing chips consisting of nanofabricated silico ...

IEEE2017

Rich cell-type-specific network topology in neocortical microcircuitry

Henry Markram, Eilif Benjamin Muller, Idan Segev, Srikanth Ramaswamy, Michael Reimann

Uncovering structural regularities and architectural topologies of cortical circuitry is vital for understanding neural computations. Recently, an experimentally constrained algorithm generated a dense network reconstruction of a similar to 0.3-mm(3) volum ...

Nature Publishing Group2017

Synaptic patterning and the timescales of cortical dynamics

Alexander Kevin Seeholzer

Neocortical circuits, as large heterogeneous recurrent networks, can potentially operate and process signals at multiple timescales, but appear to be differentially tuned to operate within certain temporal receptive windows. The modular and hierarchical or ...

Elsevier2017

Neuromorphic Architecture with 1M Memristive Synapses for Detection of Weakly Correlated Inputs

Yusuf Leblebici, Severin Sidler, Stanislaw Andrzej Wozniak, Angeliki Pantazi

Neuromorphic computing takes inspiration from the brain to build highly parallel, energy- and area-efficient architectures. Recently, hardware realizations of neurons and synapses using memristive devices were proposed and applied for the task of correlati ...

Ieee-Inst Electrical Electronics Engineers Inc2017

Morphological Diversity Strongly Constrains Synaptic Connectivity and Plasticity

Henry Markram, Eilif Benjamin Muller, Srikanth Ramaswamy, Michael Reimann

Synaptic connectivity between neurons is naturally constrained by the anatomical overlap of neuronal arbors, the space on the axon available for synapses, and by physiological mechanisms that form synapses at a subset of potential synapse locations. What i ...

Oxford University Press (OUP)2017

Hebbian plasticity requires compensatory processes on multiple timescales

Wulfram Gerstner, Friedemann Zenke

We review a body of theoretical and experimental research on Hebbian and homeostatic plasticity, starting from a puzzling observation: while homeostasis of synapses found in experiments is a slow compensatory process, most mathematical models of synaptic p ...

Royal Soc2017

Cortical afferents onto the nucleus Reticularis thalami promote plasticity of low-threshold excitability through GluN2C-NMDARs

Simone Astori

Thalamus and cortex represent a highly integrated processing unit that elaborates sensory representations. Interposed between cortex and thalamus, the nucleus Reticularis thalami (nRt) receives strong cortical glutamatergic input and mediates top-down inhi ...

Nature Research2017