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Concept

Brain ischemia

Publications associées (32)

Hyperpolarized C-13 Magnetic Resonance Spectroscopy Reveals the Rate-Limiting Role of the Blood-Brain Barrier in the Cerebral Uptake and Metabolism of L-Lactate in Vivo

Arnaud Comment, Bernard Lanz, Josefina Adriana Maria Bastiaansen, Tian Cheng, Mor-Miri Mishkovsky, Hikari Ananda Infinity Yoshihara, Yuhei Takado, Sylvain Eric Lengacher

The dynamics of L-lactate transport across the blood-brain barrier (BBB) and its cerebral metabolism are still subject to debate. We studied lactate uptake and intracellular metabolism in the mouse brain using hyperpolarized C-13 magnetic resonance spectro ...

2018

Comparison of Regularization Techniques for Microwave Imaging of Brain Stroke

Jean-Philippe Thiran, Michael Mattes, Benjamin Fuchs, Mina Bjelogrlic

This paper studies the performance of three wellknown regularization techniques to solve the inverse problem encountered in differential microwave imaging for brain stroke applications. Reconstructions from a multi-illumination configuration based on measu ...

2018

Microwave Imaging of Brain Stroke : Contributions to Modeling and Inverse Problem Resolution

Mina Bjelogrlic

Brain stroke is an age-related illness which has become a major issue in our ageing societies. Early diagnosis and treatment are of high importance for the full recovery of the patient, as reminded in Anglo-Saxon countries by the abbreviation FAST (Face, A ...

EPFL2018

Brain imaging of locomotion in neurological conditions

Dimitri Nestor Alice Van De Ville, Elvira Pirondini

Impaired locomotion is a frequent and major source of disability in patients with neurological conditions. Different neuroimaging methods have been used to understand the brain substrates of locomotion in various neurological diseases (mainly in Parkinson' ...

ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER2018

Neuroplastic Changes Following Brain Ischemia and their Contribution to Stroke Recovery: Novel Approaches in Neurorehabilitation

Silvestro Micera

Ischemic damage to the brain triggers substantial reorganization of spared areas and pathways, which is associated with limited, spontaneous restoration of function. A better understanding of this plastic remodeling is crucial to develop more effective str ...

Frontiers Media Sa2017

Progress towards in vivo brain (13)C-MRS in mice: Metabolic flux analysis in small tissue volumes

Rolf Gruetter, Bernard Lanz, Marta Lai

The combination of dynamic (13)C MRS data under infusion of (13)C-labeled substrates and compartmental models of cerebral metabolism enabled in vivo measurement of metabolic fluxes with a quantitative and distinct determination of cellular-specific activit ...

Elsevier2017

Brain metabolic alterations in mice subjected to postnatal traumatic stress and in their offspring

João Miguel das Neves Duarte, Alberto Corcoba

Adverse environmental and social conditions early in life have a strong impact on health. They are major risk factors for mental diseases in adulthood and, in some cases, their effects can be transmitted across generations. The consequences of detrimental ...

Sage Publications Inc2017

In vivo cerebral metabolism of glioblastoma xenografts assessed with ¹H MRS, ¹³C MRS and ¹⁸F-FDG PET

Marta Lai

Magnetic resonance spectroscopy (MRS) is a powerful tool when studying metabolism in intact and living organs preserving cells in their natural microenvironment with minimal external interference. The unique insights offered by the observation of metabolic ...

EPFL2017

Lactate and Glutamate dynamics during prolonged stimulation of the rat barrel cortex suggest adaptation of cerebral glucose and oxygen metabolism

João Miguel das Neves Duarte, Nathalie Just, Sarah Catherine Sonnay

A better understanding of BOLD responses stems from a better characterization of the brain’s ability to metabolize glucose and oxygen. Non-invasive techniques such as functional magnetic resonance spectroscopy (fMRS) have thus been developed allowing for t ...

Elsevier2017

Dorsal and ventral stream contributions to form-from-motion perception in a patient with form-from motion deficit: a case report

Olaf Blanke

The main model of visual processing in primates proposes an anatomo-functional distinction between the dorsal stream, specialized in spatio-temporal information, and the ventral stream, processing essentially form information. However, these two pathways a ...

2017

Decoding of Self-paced Lower-Limb Movement Intention: A Case Study on the Influence Factors

José del Rocio Millán Ruiz, Ricardo Andres Chavarriaga Lozano, Dong Liu

Brain-machine interfaces (BMIs) have been applied as new rehabilitation tools for motor disabled individuals. Active involvement of cerebral activity has been shown to enhance neuroplasticity and thus to restore mobility. Various studies have focused on th ...

Frontiers Research Foundation2017

Study of cortical energy metabolism during sensory stimulation-induced brain activity by ¹³C magnetic resonance spectroscopy in vivo

Sarah Catherine Sonnay

Cerebral function is associated with high metabolic activity that is supported by continuous supply of oxygen and glucose from the blood. Coupling between brain energy metabolism and neuronal activity has been studied extensively during the past decades. N ...

EPFL2017