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Concept

Neuromodulation (medicine)

Publications associées (32)

A 16-Channel 60µW Neural Synchrony Processor for Multi-Mode Phase-Locked Neurostimulation

Mahsa Shoaran, Uisub Shin, Cong Ding, Laxmeesha Somappa

Measuring neural oscillatory synchrony facilitates our understanding of complex brain networks and the underlying pathological states. Altering the cross-regional synchrony-as a measure of brain network connectivity-via phase-locked deep brain stimulation ...

IEEE2022

The aging brain as a model to understand motor skill acquisition in humans and its restoration using non-invasive brain stimulation

Pablo Maceira Elvira

Motor skill acquisition is essential to our survival, as it enables an efficient interaction with the changing world around us. The acquisition of novel sequential tasks, of particular relevance due to their pervasiveness in everyday life activities, can b ...

EPFL2022

Sensor-based control strategies for integration of epidural electrical stimulation in rehabilitation after spinal cord injury

Miroslav Caban

Spinal Cord Injury (SCI) results in damage to neural circuitry connecting the brain to the periphery. Consequently, sensory and motor function is lost, to varying degree, depending on the site and severity of the lesion. More than half of spinal cord injur ...

EPFL2022

Development of a peripheral neuroprosthesis to elicit fine hand movements in primates

Marion Aimée Geneviève Badi-Dubois

Neurological disorders such as spinal cord lesion and stroke disturb sensorimotor pathways and result in severe motor deficits that can dreadfully impact the quality of life of affected individuals. Strategies aiming at restoring hand function after upper- ...

EPFL2021

Resource Trade-Offs in Circuits and Systems: from Neurotechnology to Communications

Arda Uran

This thesis aims to explore and exploit trade-offs in integrated circuits and systems to overcome the fundamental bottlenecks faced by future data acquisition and communication systems. Specifically, we target the emerging implantable neurotechnology and t ...

EPFL2021

Predictive models for response to non-invasive brain stimulation in stroke: A critical review of opportunities and pitfalls

Friedhelm Christoph Hummel, Maximilian Jonas Wessel, Philip Egger

Background: Noninvasive brain stimulation has been successfully applied to improve stroke impairments in different behavioral domains. Yet, clinical translation is limited by heterogenous comes within and across studies. It has been proposed to develop and ...

ELSEVIER SCIENCE INC2021

Neural interface systems with on-device computing: machine learning and neuromorphic architectures

Mahsa Shoaran

Development of neural interface and brain-machine interface (BMI) systems enables the treatment of neurological disorders including cognitive, sensory, and motor dysfunctions. While neural interfaces have steadily decreased in form factor, recent developme ...

CURRENT BIOLOGY LTD2021

A 16-Channel Wireless Neural Recording System-on-Chip with CHT Feature Extraction Processor in 65nm CMOS

Yusuf Leblebici, Volkan Cevher, Stéphanie Lacour, Catherine Dehollain, Florian Dylan Fallegger, Cosimo Aprile, Kerim Türe, Alix Esther Anne Trouillet, Arda Uran

Wireless implantable neural recording chips enable multichannel data acquisition with high spatiotemporal resolution in situ. Recently, the use of machine learning approaches on neural data for diagnosis and prosthesis control have renewed the interest in ...

2021

Impaired reach-to-grasp kinematics in parkinsonian patients relates to dopamine-dependent, subthalamic beta bursts

Silvestro Micera

Excessive beta-band oscillations in the subthalamic nucleus are key neural features of Parkinson's disease. Yet the distinctive contributions of beta low and high bands, their dependency on striatal dopamine, and their correlates with movement kinematics a ...

NATURE RESEARCH2021

Bioelectronic medicine for the autonomic nervous system: clinical applications and perspectives

Silvestro Micera, Ivo Strauss

Bioelectronic medicine (BM) is an emerging new approach for developing novel neuromodulation therapies for pathologies that have been previously treated with pharmacological approaches. In this review, we will focus on the neuromodulation of autonomic nerv ...

IOP PUBLISHING LTD2021

A machine-learning algorithm correctly classifies cortical evoked potentials from both visual stimulation and electrical stimulation of the optic nerve

Diego Ghezzi, Eleonora Borda, Vivien Gaillet, Elodie Geneviève Zollinger

Objective. Optic nerve's intraneural stimulation is an emerging neuroprosthetic approach to provide artificial vision to totally blind patients. An open question is the possibility to evoke individual non-overlapping phosphenes via selective intraneural op ...

IOP PUBLISHING LTD2021

Hand Control With Invasive Feedback Is Not Impaired by Increased Cognitive Load

Silvestro Micera, Ivo Strauss, Giacomo Valle, Francesco Maria Petrini, Edoardo D'Anna

Recent experiments have shown that neural stimulation can successfully restore sensory feedback in upper-limb amputees improving their ability to control the prosthesis. However, the potential advantages of invasive sensory feedback with respect to non-inv ...

2020