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Reversion of P-gp-Mediated Drug Resistance in Ovarian Carcinoma Cells with PHPMA-Zosuquidar Conjugates

Inhibition of P-glycoprotein (P-gp) transporter is an attractive approach for the reversion of cancer-associated multidrug resistance (MDR). Poly(N-(2-hydroxypropyl) methacrylamide) (PHPMA)-based carriers that are able to release the anticancer drug doxoru ...

American Chemical Society2017

Multipactor theory for multi-carrier signals

Michael Mattes

This work presents a new theory of multipactor under multi-carrier signals for parallel-plate geometries. It is the generalization of the non-stationary multipactor theory for single-carrier signals1. It is valid for multicarrier signals with an arbitrary ...

American Institute of Physics2011

Nanoparticle conjugation of antigen enhances cytotoxic T-cell responses in pulmonary vaccination

Jeffrey Alan Hubbell, Melody Swartz, Marie Ballester

The ability of vaccines to induce memory cytotoxic T-cell responses in the lung is crucial in stemming and treating pulmonary diseases caused by viruses and bacteria. However, most approaches to subunit vaccines produce primarily humoral and only to a less ...

National Academy of Sciences2011

Charged excitons in modulation-doped quantum wires

Elyahou Kapon, Benjamin Dwir, Marc-André Dupertuis, Daniel Oberli, Nicolas Moret, Tim Otterburg

We report on the observation of negatively- and positively-charged excitons in the photoluminescence spectra of V-groove quantum wires. The. charged exciton binding energy increases with the strength of the quantum confinement. We demonstrate that fluctuat ...

American Institute of Physics2005