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Concept

Quantitative phase-contrast microscopy

Publications associées (29)

Spatially-Variant CNN-Based Point Spread Function Estimation for Blind Deconvolution and Depth Estimation in Optical Microscopy

Michael Stefan Daniel Liebling, Adrian Shajkofci

Optical microscopy is an essential tool in biology and medicine. Imaging thin, yet non-flat objects in a single shot (without relying on more sophisticated sectioning setups) remains challenging as the shallow depth of field that comes with high-resolution ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2020

Optical phase contrast imaging of human retinal cells by changing the tissue refractive index

Christophe Moser, Timothé Laforest, Laura Emmanuelle Kowalczuk, Mathieu Künzi

Purpose : Based on oblique partially coherent illumination of transparent samples, we developed a simple custom Optical Phase Imaging (OPI) microscope providing a label-free, semi-quantitative phase contrast imaging. The aim of this study was to explore th ...

ASSOC RESEARCH VISION OPHTHALMOLOGY INC2020

All-Dielectric Programmable Huygens' Metasurfaces

Hatice Altug, Andreas Tittl, Aleksandrs Leitis

Low-loss nanostructured dielectric metasurfaces have emerged as a breakthrough platform for ultrathin optics and cutting-edge photonic applications, including beam shaping, focusing, and holography. However, the static nature of their constituent materials ...

2020

Time-lapse high-resolution microscopy to study the morphogenesis of microorganisms

Mélanie Thérèse Marie Hannebelle

Mycobacterium tuberculosis, the etiological agent for the tuberculosis disease, is a bacterial pathogen thought to infect about a quarter of the global human population. It is the first cause of death among infectious diseases, and is most prevalent in low ...

EPFL2020

High-resolution interference microscopy of binary phase diffractive optical elements

Toralf Scharf, Dong Cheon Kim, Michail Symeonidis

In this work, we apply the high-resolution interference microscopy technique to investigate the intensity and phase of light transmitted through a binary phase element. Using a combination of simulation and experimental results, we identify specific featur ...

2019

Bretherton's buoyant bubble

John Martin Kolinski, Wassim Dhaouadi

When a buoyant bubble is inserted into a closed capillary that is slightly smaller than the capillary length, it appears stuck; exactly why this is so is a puzzle that has remained unanswered over the past 50 years. Recent calculations suggest that the bub ...

2019

Novel daylighting system based on advanced embedded optical microstructures for various facade orientation and climates

Jing Gong

The design of highly glazed building has become a worldwide trend in modern architecture. However, glazing may induce large thermal loss in winter while increase cooling load in summer, and it may also cause glare. In order to solve the problems, a novel m ...

EPFL2019

Biomedical optical techniques for intracochlear cellular imaging

Marilisa Romito

Imaging the inner ear microanatomy is of great importance for the assessment of the state of the cells responsible for sound detection. Hearing disorders are mainly due to a malfunction of the cochlea, the bone containing the cells inside the inner ear. Un ...

EPFL2019

Phase resolved characterization of nanoscale features in optical microstructures

Michail Symeonidis

In this study, we apply interferometric microscopy to study the phase, alongside the intensity, of the light field transmitted through a wide variety of samples. Additionally, we conduct those interferometric measurements at different wavelengths within th ...

EPFL2019