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Concept

Glossary of biology

Publications associées (13)

Ultraviolet Superradiance from Mega-Networks of Tryptophan in Biological Architectures

Majed Chergui, Katrin Elisabeth Oberhofer

Networks of tryptophan (Trp)& horbar;an aromatic amino acid with strong fluorescence response & horbar;are ubiquitous in biological systems, forming diverse architectures in transmembrane proteins, cytoskeletal filaments, subneuronal elements, photorecepto ...

Amer Chemical Soc2024

Exosomes, microvesicles, and other extracellular vesicles-a Keystone Symposia report

Michele De Palma, Wei Guo

Extracellular vesicles (EVs) are small, lipid-bilayer-bound particles released by cells that can contain important bioactive molecules, including lipids, RNAs, and proteins. Once released in the extracellular environment, EVs can act as messengers locally ...

WILEY2023

V-ATPase/TORC1-mediated ATFS-1 translation directs mitochondrial UPR activation in C. elegans

Johan Auwerx, Kristina Schoonjans, Felix Naef, Xiaoxu Li, Yang Li, Hao Li, Jia Liu, Yan Liu, Wen Gao, Amélia Lalou, Nagammal Neelagandan

To adapt mitochondrial function to the ever-changing intra- and extracellular environment, multiple mitochondrial stress response (MSR) pathways, including the mitochondrial unfolded protein response (UPRmt), have evolved. However, how the mitochondrial st ...

Rockefeller University Press2022

Employing bacterial mutations for the elucidation of photo-Fenton disinfection: Focus on the intracellular and extracellular inactivation mechanisms induced by UVA and H2O2

César Pulgarin, Stefanos Giannakis

The bacterial inactivation mechanisms by solar light and the photo-Fenton process is still a matter of debate. In this study, we bring evidence towards the elucidation of the mechanisms that govern photo-Fenton disinfection at near-neutral pH. With the use ...

PERGAMON-ELSEVIER SCIENCE LTD2020

Controlling and Monitoring Intracellular Drug Delivery Using PHPMA-Based Polymer Nanomedicines

Claudia Battistella

Polymer nanomedicine is an attractive approach for the delivery of anticancer drugs. Firstly designed to increase drug bioavailability, polymer conjugates and polymer nanoparticles have rapidly emerged in the field of cancer therapy after the discovery of ...

EPFL2017

Sodium Signaling and Astrocyte Energy Metabolism

Pierre Magistretti

The Na+ gradient across the plasma membrane is constantly exploited by astrocytes as a secondary energy source to regulate the intracellular and extracellular milieu, and discard waste products. One of the most prominent roles of astrocytes in the brain is ...

Wiley-Blackwell2016

Carbon-based smart nanomaterials in biomedicine and neuroengineering

Michele Giugliano

The search for advanced biomimetic materials that are capable of offering a scaffold for biological tissues during regeneration or of electrically connecting artificial devices with cellular structures to restore damaged brain functions is at the forefront ...

Beilstein-Institut2014

Cd and Pb removal from contaminated environment by metal resistant bacterium Cupriavidus metallidurans CH34: importance of the complexation and competition effects

Vera Slaveykova-Startcheva

The present study aims to improve the understanding of the role of complexation and competition effects on Cd and Pb accumulation by the metal resistant bacterium Cupriavidus metallidurans largely used in bioremediation. Adsorbed and intracellular metal co ...

Csiro Publishing2012

Cu and Pb accumulation by the marine diatom Thalassiosira weissflogii in the presence of humic acids

Vera Slaveykova-Startcheva

Metal complexation by dissolved organic matter, as humic acids, is considered to decrease metal bioavailability by lowering the free metal ion concentration. However, dissolved organic matter adsorption on cell surfaces can modify cell membrane properties, ...

2010

Impact of Mycobacterium ulcerans biofilm on transmissibility to ecological niches and Buruli ulcer pathogenesis

Stewart Cole, Petra Tafelmeyer

The role of biofilms in the pathogenesis of mycobacterial diseases remains largely unknown. Mycobacterium ulcerans, the etiological agent of Buruli ulcer, a disfiguring disease in humans, adopts a biofilm-like structure in vitro and in vivo, displaying an ...

2007

Effects of dynamic environments on extracellular morphogen gradients

Mark Fleury

Tissue morphogenesis and remodeling is often orchestrated by cell-secreted proteins, referred to as morphogens that can trigger cellular responses in addition to modifying the local extracellular matrix (ECM). Of specific interest is the distribution of ce ...

EPFL2007

Masters and servants of the force: the role of matrix adhesions in myofibroblast force perception and transmission

Boris Hinz

Fibroblast-to-myofibroblast differentiation - a key event in the development of fibrocontractive diseases and in wound granulation tissue contraction - is hallmarked by the formation of stress fibers and the neo-expression of alpha-smooth muscle actin. Inc ...

Elsevier2006

Mechanobiology in the third dimension

Melody Swartz

Cells are mechanically coupled to their extracellular environments, which play critical roles in both communicating the state of the mechanical environment to the cell as well as in mediating cellular response to a variety of stimuli. Along with the molecu ...

Kluwer Academic Publishers, Springer2005