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Concept

Composé spiro

Publications associées (27)

Cyclization and Cycloaddition Reactions of Cyclopropyl Carbonyls and Imines

Jérôme Waser, Filippo De Simone

Activated cyclopropanes, such as vinyl and carbonyl cyclopropanes, are useful building blocks in organic chemistry due to their exceptional reactivity. This review focuses on the use of cyclopropyl carbonyls and imines in cyclization and cycloaddition reac ...

Georg Thieme Verlag2009

Search for new anti-cancer heterocyclic compounds

Tumors consist of cells whose growth and morphological characteristics are markedly different from those of normal cells. Observation of human and animal models argue that tumor development proceeds via a process formally analogous to Darwinian evolution, ...

EPFL2009

{2,2 '-[1,1 '-(3-Azapentane-1,5-diyldinitrilo)diethylidyne] diphenolato}(piperidine) cobalt(III) tetraphenylborate

Kurt Schenk

The title compound, Co(C20H23N3O2)(C5H11N) or [Co{(Me-sal)(2)dien}(pprdn)] BPh4, where (Me-sal) 2dien is 2,2'[1,1'-(3-azapentane-1,5-diyldinitrilo)diethylidyne]diphenolate and pprdn is piperidine, contains a pentadentate (Me-sal) 2dien ligand fu ...

2008

Position-flexible elaboration of halogenated heterocycles: Metalated species as key intermediates for synthesis

Halogens, in particular fluorine atoms, are favorite tools to fine-tune the chemical and biological properties of pharmaceutical or agricultural development products. At the same time, such an electronegative substituent can effectively assist the site-sel ...

2007

Investigations of Diels-Alder reactions in ionic liquids

Ana Vidis

Room temperature ionic liquids comprise an unique class of solvent composed of organic and inorganic-based ions that are molten under ambient conditions. They are characterised by high solvent polarity and low vapour pressure, and can be tailored to have s ...

EPFL2007

New efficient synthetic routes toward functionalised polyketides : application to the preparation of analogues of bioactive natural compounds

Gérald Coste

RNA plays key roles in essential biological processes, such as protein synthesis, transcriptional regulation, splicing and retroviral replication. The structural diversity of RNA molecules and the lack of known RNA repair mechanisms make these biopolymers ...

EPFL2007

Heterocyclic compounds and their use as antifouling agents

Karl Gademann

The present invention relates to a nostocarboline compound and its use as biocidal agent. ...

2005