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Concept

Immunoglobuline anti-D

Publications associées (14)

Investigation on the Role of Pd, Pt, Rh in Methane Abatement for Heavy Duty Applications

Oliver Kröcher, Davide Ferri, Moyu Wang

Methane abatement remains a challenge in aftertreatment systems of natural gas engines, currently under discussion in combination with synthetic methane. In this study, Pt/Rh and Pd/Rh-based three-way catalysts are investigated under various transient cond ...

MDPI2022

Electrical Signal Modeling in Cochlear Implants. Study of Temperature and Humidity Effects

Maria-Alexandra Paun

The present paper discusses the climatic effects of humidity and temperature on cochlear implant functioning and the quality of the electrical sound signal. MATLAB Simulink simulations were prepared, offering insights into signal behavior under such climat ...

MDPI2021

The Contorsbody, an antibody format for agonism: design, structure, and function

Henning Paul-Julius Stahlberg

The careful design of the antibody architecture is becoming more and more important, especially when the purpose is agonism. We present the design of a novel antibody format that is able to promote receptor dimerization and induce signal transduction resul ...

2020

Functional de novo Protein Design for Targeted Vaccines and Synthetic Biology Applications

Che Yang

Evolution has created, selected and evolved large repertoires of proteins that operate in various biological systems. Nowadays biotechnological needs are coming up orders of magnitude faster than proteins naturally evolve. The emergence of de novo protein ...

EPFL2020

Genetic determinants of healthy human immune variance: from humoral response to microbiome diversity

Petar Scepanovic

Identifying the drivers of the observed interindividual variability of the human immune system is crucial to our understanding of infectious and immune-mediated diseases. The contribution of genetic and non-genetic factors to immunological differences betw ...

EPFL2018

An electron acceptor molecule in a nanomesh: F(4)TCNQ on h-BN/Rh(111)

Silvan Dino Marcos Roth, Huanyao Cun

The adsorption of molecules on surfaces affects the surface dipole and thus changes in the work function may be expected. The effect in change of work function is particularly strong if charge between substrate and adsorbate is involved. Here we report the ...

ELSEVIER SCIENCE BV2018

An electrochemical sensor for quantitative analysis of Rhesus D antibodies in blood

Giovanni De Micheli, Sandro Carrara, Irene Taurino, Francesca Criscuolo, Tugba Kilic

The Hemolytic Disease of the Fetus and Newborn (HDFN), if untreated, can have severe consequences on baby’s health, eventually causing death. Prevention and diagnosis of pregnancies at risk of HDFN consists in quantitative analysis in hospital every 2-4 we ...

IEEE2017

Fostering of advanced mutualism with gut microbiota by Immunoglobulin A

Duncan-Bruce Sutherland

Immunoglobulin A (IgA), the most abundantly secreted antibody isotype in mammals, not only provides direct immune protection to neonates via maternal milk but also helps program the infant immune system by regulating the microbiota. IgA continues to mainta ...

Wiley-Blackwell2016

Sensitive and fast identification of bacteria in blood samples by immunoaffinity mass spectrometry for quick BSI diagnosis

Hubert Girault, Horst Pick, Liang Qiao, Natalia Gasilova, Alexandra Bondarenko, Niels Erik Lion, Michel Prudent, Yingdi Zhu

Bloodstream infections rank among the most serious causes of morbidity and mortality in hospitalized patients, partly due to the long period (up to one week) required for clinical diagnosis. In this work, we have developed a sensitive method to quickly and ...

Royal Soc Chemistry2016

Concerted Activity of IgG1 Antibodies and IL-4/IL-25-Dependent Effector Cells Trap Helminth Larvae in the Tissues following Vaccination with Defined Secreted Antigens, Providing Sterile Immunity to Challenge Infection

Nicola Harris, Julia Esser-von Bieren

Over 25% of the world's population are infected with helminth parasites, the majority of which colonise the gastrointestinal tract. However, no vaccine is yet available for human use, and mechanisms of protective immunity remain unclear. In the mouse model ...

Public Library of Science2015

Highly cytotoxic trithiolato-bridged dinuclear Rh(III) and Ir(III) complexes

Paul Joseph Dyson, Benjamin Samuel Murray

Water soluble trithiolato-bridged cationic complexes of the type (eta(5)-C5Me5)(2)M-2(mu-SC6H4-p-X)(3) (M = Rh, X = H, 1; CH3, 3; OCH3, 5; Pr-i, 7; Bu-t, 9; M Ir, X = H, 2; CH3, 4; OCH3, 6; Pr-i, 8; Bu-t, 10) were synthesized and isolated as their chl ...

Elsevier Science Sa2014

Synthesis, molecular structure, computational study and in vitro anticancer activity of dinuclear thiolato-bridged pentamethylcyclopentadienyl Rh(III) and Ir(III) complexes

Paul Joseph Dyson, Benjamin Samuel Murray

Neutral dinuclear dithiolato-bridged pentamethylcyclopentadienyl Rh(III) complexes of the type (C5Me5)(2)Rh-2(mu-SR)(2)Cl-2 (R = CH2Ph, 1; R = CH2CH2Ph, 2) and cationic dinuclear trithiolato-bridged pentamethylcyclopentadienyl Rh(III) and Ir(III) complexes ...

Royal Society of Chemistry2013

The ITER EC H&CD Upper Launcher: Maintenance concepts

René Chavan, Jean-Daniel Landis

Maintenance of the ITER EC H&CD Upper Launcher (UL) shall be performed through the use of Remote Handling (RH) in the ITER Hot Cell Facility (HCF). The UL design will have to be fully compliant with ITER RH maintenance requirements and the set of RH toolin ...

Elsevier Science Sa2013

Immunoisolated cell implants for intracerebral delivery of anti-Aß single chain Fv antibodies in the APP23 Alzheimer's mouse model

Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in the elderly population. AD currently affects approximately 27 million people worldwide. A pathological hallmark of AD is the accumulation and deposition of the amyloid beta (Aβ) pe ...

EPFL2009