Dexaméthasone

Circadian Regulation of Cochlear Sensitivity to Noise by Circulating Glucocorticoids

Benjamin Dieter Weger, Frédéric Bruno Martin Gachon

The cochlea possesses a robust circadian clock machinery that regulates auditory function. How the cochlear clock is influenced by the circadian system remains unknown. Here, we show that cochlear rhythms are system driven and require local Bmal1 as well a ...

2019

Increased brain glucocorticoid actions following social defeat in rats facilitates the long-term establishment of social subordination

Maria del Carmen Sandi Perez, Jocelin Grosse, Olivia Zanoletti, Meltem Weger

Social rank is frequently established through aggressive encounters between new conspecifics. Despite increasing evidence suggesting that social rank is critical for the well-being of both humans and animals, knowledge about the factors influencing social ...

2018

Monitoring the effects of dexamethasone treatment by MRI using in vivo iron oxide nanoparticle-labeled macrophages

Heinrich Hofmann, Lionel André Maurizi, Géraldine Sylvie Coullerez

Introduction: Rheumatoid arthritis (RA) is a chronic disease causing recurring inflammatory joint attacks. These attacks are characterized by macrophage infiltration contributing to joint destruction. Studies have shown that RA treatment efficacy is correl ...

Biomed Central Ltd2014

Increased corticosterone in peripubertal rats leads to long-lasting alterations in social exploration and aggression

Maria del Carmen Sandi Perez, Maria Isabel Cordero Campana, Stamatina Tzanoulinou, Vandana Veenit

Stress during childhood and adolescence enhances the risk of psychopathology later in life. We have previously shown that subjecting male rats to stress during the peripubertal period induces long-lasting effects on emotion and social behaviors. As cortico ...

Frontiers Research Foundation2013