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Concept

Signal BOLD

Publications associées (31)

Impact of a mindfulness-based intervention on neurobehavioral functioning and its association with large-scale brain networks in preterm young adolescents

Dimitri Nestor Alice Van De Ville, Vanessa Siffredi

Aim: Adolescents born very preterm (VPT;

Wiley2024

An optimized protocol for assessing changes in mouse whole-brain activity using opto-fMRI

Valerio Zerbi, Christina Maria Grimm

Functional magnetic resonance imaging (fMRI) in mouse brain, paired with spatially and temporally defined manipulations, offers a powerful tool to causally explain the effect of specific neuronal activity on brain network dynamics. Here, we present an opti ...

ELSEVIER2022

Unraveling brain interactions in vision: the example of crowding

Michael Herzog, Vitaly Chicherov, Maya Anna Jastrzebowska

Crowding, the impairment of target discrimination in clutter, is the standard situation in vision. Traditionally, crowding is explained with (feedforward) models, in which only neighboring elements interact, leading to a “bottleneck” at the earliest stages ...

2021

The relationship between EEG and fMRI connectomes is reproducible across simultaneous EEG-fMRI studies from 1.5T to 7T

Rolf Gruetter, François Lazeyras, João Pedro Forjaco Jorge

Both electroencephalography (EEG) and functional Magnetic Resonance Imaging (fMRI) are non-invasive methods that show complementary aspects of human brain activity. Despite measuring different proxies of brain activity, both the measured blood-oxygenation ...

2021

Non-exponential magnetic relaxation in magnetic nanoparticles for hyperthermia

Ferenc Simon

Magnetic nanoparticle based hyperthermia emerged as a potential tool for treating malignant tumours. The efficiency of the method relies heavily on the knowledge of magnetic properties of the samples; in particular, knowledge of the frequency dependent com ...

2021

Brainstem Correlates of a Cold Pressor Test Measured by Ultra-High Field fMRI

Dimitri Nestor Alice Van De Ville, Sandra Elisabete Monney, Olivier Benoit Thomas Reynaud, Domenica Bueti

Introduction Modern imaging techniques such as blood oxygen level-dependent (BOLD) functional magnetic resonance imaging (fMRI) allow the non-invasive and indirect measurement of brain activity. Whether changes in signal intensity can be detected in small ...

2020

Context effects on probability estimation

Wei-Hsiang Lin

Many decisions rely on how we evaluate potential outcomes and estimate their corresponding probabilities of occurrence. Outcome evaluation is subjective because it requires consulting internal preferences and is sensitive to context. In contrast, probabili ...

PUBLIC LIBRARY SCIENCE2020

Dynamics of brain function in preterm-born young adolescents

Lorena Gonçalves de Alcântara e Freitas Krikler

Preterm birth is a major risk factor for neurodevelopment impairments often only appearing later in life. The brain is still at a high rate of development during adolescence, making this a promising window for intervention. It is thus crucial to understand ...

EPFL2020

Normalization of aberrant pretherapeutic dynamic functional connectivity of extrastriate visual system in patients who underwent thalamotomy with stereotactic radiosurgery for essential tremor: a resting-state functional MRI study

Jean-Philippe Thiran, Dimitri Nestor Alice Van De Ville, Meritxell Bach Cuadra, Constantin Tuleasca, Thomas William Arthur Bolton

OBJECTIVE The tremor circuitry has commonly been hypothesized to be driven by one or multiple pacemakers within the cerebello-thalamo-cortical pathway, including the cerebellum, contralateral motor thalamus, and primary motor cortex. However, previous stud ...

2020

Repetitive Erythropoietin Treatment Improves Long-Term Neurocognitive Outcome by Attenuating Hyperoxia-Induced Hypomyelination in the Developing Brain

Yohan Van de Looij

Introduction:Preterm infants born before 28 weeks of gestation are at high risk of neurodevelopmental impairment in later life. Cerebral white and gray matter injury is associated with adverse outcomes. High oxygen levels, often unavoidable in neonatal int ...

FRONTIERS MEDIA SA2020

Metabolic and hemodynamic changes in the activated human brain and cerebellar organisation measured by MRS/MRl at 7 Tesla

Yohan Boillat

Although less often investigated than the positive blood-oxygen-level-dependent (BOLD) signal, a negative BOLD signal has also been observed under certain conditions, which could have a neuronal origin. To further investigate the negative BOLD signal from ...

EPFL2020

Multi-slice passband bSSFP for human and rodent fMRI at ultra-high field

Rolf Gruetter, Ileana Ozana Jelescu, Rodrigo Araujo Fraga Da Silva, Olivier Benoit Thomas Reynaud

Balanced steady-state free precession (bSSFP) can be used as an alternative to gradient-echo (GE) EPI for BOLD functional MRI when image distortions and signal drop-outs are severe such as at ultra-high field. However, 3D-bSSFP acquisitions have distinct d ...

Academic Press Inc - Elsevier Science2019

Metabolite concentration changes associated with positive and negative BOLD responses in the human visual cortex: A functional MRS study at 7 Tesla

Rolf Gruetter, Lijing Xin, Wietske Van der Zwaag, Yohan Boillat

Negative blood oxygenation-level dependent (BOLD) signal observed during task execution in functional magnetic resonance imaging (fMRI) can be caused by different mechanisms, such as a blood-stealing effect or neuronal deactivation. Electrophysiological re ...

2019

Whole brain measurements of the positive BOLD response variability during a finger tapping task at 7 T show regional differences in its profiles

Wietske Van der Zwaag, Yohan Boillat

PURPOSE: The positive BOLD response can vary across brain regions. Here, the positive BOLD responses of motor regions, including the cerebellum, were investigated by fast fMRI acquisition. METHODS: The participants were asked to perform an event-related fi ...

Wiley2019

Functional imaging of rostrocaudal spinal activity during upper limb motor tasks

Dimitri Nestor Alice Van De Ville, Silvestro Micera, Roberto Martuzzi, Elvira Pirondini, Nawal Noëlle Kinany

The spinal cord is the main interface between the brain and the periphery. It notably plays a central role in motor control, as spinal motoneurons activate skeletal muscles involved in voluntary movements. Yet, the spinal mechanisms underlying human moveme ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2019

The dynamic functional connectome: State-of-the-art and perspectives

Dimitri Nestor Alice Van De Ville, Maria Giulia Preti, Thomas William Arthur Bolton

Resting-state functional magnetic resonance imaging (fMRI) has highlighted the rich structure of brain activity in absence of a task or stimulus. A great effort has been dedicated in the last two decades to investigate functional connectivity (FC), i.e. th ...

Elsevier2017

Disentangling resting-state BOLD variability and PCC functional connectivity in 22q11.2 deletion syndrome

Dimitri Nestor Alice Van De Ville, Marie Schaer, Daniela Maria Zöller

Although often ignored in fMRI studies, moment-to-moment variability of blood oxygenation level dependent (BOLD) signals reveals important information about brain function. Indeed, higher brain signal variability has been associated with better cognitive p ...

Elsevier2017

Influence of physiological noise on accelerated 2D and 3D resting state functional MRI data at 7 T

Rolf Gruetter, Wietske Van der Zwaag, José Pedro Rebelo Ferreira Marques, João Pedro Forjaco Jorge, Olivier Benoit Thomas Reynaud

Physiological noise often dominates the blood-oxygen level-dependent (BOLD) signal fluctuations in high-field functional MRI (fMRI) data. Therefore, to optimize fMRI protocols, it becomes crucial to investigate how physiological signal fluctuations impact ...

Wiley-Blackwell2017

Precision targeting of tumor macrophages with a CD206 binding peptide

Michele De Palma, Mario Leonardo Squadrito

Tumor-associated macrophages (TAMs) expressing the multi-ligand endocytic receptor mannose receptor (CD206/MRC1) contribute to tumor immunosuppression, angiogenesis, metastasis, and relapse. Here, we describe a peptide that selectively targets MRC1-express ...

Nature Research2017

Hyperpolarized 6Li as a probe for hemoglobin oxygenation level

Rolf Gruetter, Arnaud Comment, Mor-Miri Mishkovsky, Ruud van Heeswijk, Riccardo Balzan

Hyperpolarization by dissolution dynamic nuclear polarization (DNP) is a versatile technique to dramatically enhance the nuclear magnetic resonance (NMR) signal intensity of insensitive long-T1 nuclear spins such as 6 Li. The 6 Li longitudinal relaxation o ...

Wiley-Blackwell2016