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Concept

Diaphragme (organe)

Publications associées (13)

Compliant vascular grafts and methods of use

Nikolaos Stergiopoulos, Georgios Rovas

Compliant vascular grafts for implantation in the vasculature are provided. The compliant vascular grafts are designed to expand longitudinally and radially within a blood vessel, such as an artery, and is expected to be particularly well suited for treati ...

2024

Numerical Simulation of Unreinforced Masonry Buildings with Timber Diaphragms

Katrin Beyer, Igor Tomic, Francesco Vanin, Ivana Bozulic

Though flexible diaphragms play a role in the seismic behaviour of unreinforced masonry buildings, the effect of the connections between floors and walls is rarely discussed or explicitly modelled when simulating the response of such buildings. These flexi ...

2021

Elezanumab, a human anti-RGMa monoclonal antibody, promotes neuroprotection, neuroplasticity, and neurorecovery following a thoracic hemicompression spinal cord injury in non-human primates

Grégoire Courtine, Quentin Barraud

Spinal cord injury (SCI) is a devastating condition characterized by loss of function, secondary to damaged spinal neurons, disrupted axonal connections, and myelin loss. Spontaneous recovery is limited, and there are no approved pharmaceutical treatments ...

2021

Mapping the site-specific accuracy of loop-based local pulse wave velocity estimation and reflection magnitude: a 1D arterial network model analysis

Nikolaos Stergiopoulos

Objective: Local pulse wave velocity (PWV) can be estimated from the waterhammer equation and is an essential component of wave separation analysis. However, previous studies have demonstrated inaccuracies in the estimations of local PWV due to the presenc ...

2019

Chronic low back pain patients walk with locally altered spinal kinematics

Julien Favre, Brigitte Jolles-Haeberli

Various studies have reported alterations of spinal kinematics in patients with chronic low back pain (CLBP) during gait. However, while recent findings stressed the importance of multi-segment analysis, most of prior gait studies modelled the lumbar spine ...

Elsevier Sci Ltd2017

Multi-segment analysis of spinal kinematics during sit-to-stand in patients with chronic low back pain

Julien Favre

While alterations in spinal kinematics have been frequently reported in patients with chronic low back pain (CLBP), a better characterization of the kinematics during functional activities is needed to improve our understanding and therapeutic solutions fo ...

Elsevier Sci Ltd2016

Touch-Based System for Beat-to-Beat Impedance Cardiogram Acquisition and Hemodynamic Parameters Estimation

David Atienza Alonso, Srinivasan Murali, Francisco Javier Rincon Vallejos, Dionisije Sopic

Among all cardiovascular diseases, congestive heart failure (CHF) has a very high rate of hospitalization and mortality. In order to prevent hospitalization, there is a strong need to identify patients at risk of a CHF event by estimating a set of relevant ...

IEEE/ACM Press2016

Role of a polymorphism in a Hox/Pax-responsive enhancer in the evolution of the vertebrate spine

Denis Duboule

Patterning of the vertebrate skeleton requires the coordinated activity of Hox genes. In particular, Hox10 proteins are essential to set the transition from thoracic to lumbar vertebrae because of their rib-repressing activity. In snakes, however, the thor ...

National Academy of Sciences2013

Wall properties of the apolipoprotein E-deficient mouse aorta

Nikolaos Stergiopoulos, Aristotelis Agianniotis

Objectives: We quantified the dysfunction of the aortic wall, determined structural and elastic properties, and provided histological data of the thoracic aortas of apolipoprotein E (apoE)-deficient mice which are used as model of atherosclerosis. Methods: ...

Elsevier Ireland Ltd2012

A constituent-based model of age-related changes in conduit arteries

Nikolaos Stergiopoulos, Alexander Rachev

Tsamis A, Rachev A, Stergiopulos N. A constituent-based model of age-related changes in conduit arteries. Am J Physiol Heart Circ Physiol 301: H1286-H1301, 2011. First published July 1, 2011; doi: 10.1152/ajpheart.00570.2010.-In the present report, a const ...

2011

Arterial remodeling using a constituent-based approach

This thesis is intended to contribute to the field of biomechanics of growth and remodeling of arteries. The work focuses particularly on growth and remodeling caused by sustained hypertension, increased blood flow, and ageing. A structure-based constituti ...

EPFL2010

A structure-based model of arterial remodeling in response to sustained hypertension

Nikolaos Stergiopoulos, Alexander Rachev

A novel structure-based mathematical model of arterial remodeling in response to a sustained increase in pressure is proposed. The model includes two major aspects of remodeling in a healthy matured vessel. First, the deviation of the wall stress and flow- ...

2009

Structural strain energy function applied to the ageing of the human aorta

Nikolaos Stergiopoulos, Martin Zulliger

Stiffening of the aorta with progressing age leads to decrease of aortic compliance and thus to an increase of pulse pressure amplitude. Using a strain energy function (SEF) which takes into account the composition of the arterial wall, we have studied the ...

2007