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Concept

Diagramme de boucle causale

Publications associées (21)

Specification of haematopoietic stem cell fate via modulation of mitochondrial activity

Johan Auwerx, Matthias Lütolf, Olaia Maria Naveiras Torres-Quiroga, Mukul Girotra, Vasco Ledebur de Antas de Campos, Aline Roch, Nicola Vannini, Sonja Giger, Gennady Nikitin

Haematopoietic stem cells (HSCs) differ from their committed progeny by relying primarily on anaerobic glycolysis rather than mitochondrial oxidative phosphorylation for energy production. However, whether this change in the metabolic program is the cause ...

Nature Publishing Group2016