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Publications associées (31)

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A 0.4 nJ Excitation Energy Bridge-to-Digital Converter for Implantable Pulmonary Artery Pressure Monitoring

Marco Mattavelli, Catherine Dehollain, Diego Ruben Barrettino, Kerim Türe, Mustafa Besirli

This paper presents an energy-efficient, duty-cycled, and spinning excitation bridge-to-digital converter (BDC) suitable for measuring the pulmonary artery pressure of heart failure patients with an implantable system. The duty-cycled bridge uses resistanc ...

IEEE2021

Mathematical and numerical models for the cardiac electromechanical function

Alfio Quarteroni, Francesco Regazzoni

This paper deals with the mathematical model that describes the function of the human heart. More specifically, it addresses the equations that express the electromechanical process, that is the mechanical deformation (contraction and relaxation) of the he ...

EUROPEAN MATHEMATICAL SOC-EMS2021

Association of Heart Rate Variability With Silent Brain Infarcts in Patients With Atrial Fibrillation

Jean-Marc Vesin, Vincent Schlageter

Purpose: Silent brain infarcts (SBI) are frequently detected in patients with atrial fibrillation (AF), but it is unknown whether SBI are linked to autonomic dysfunction. We aimed to explore the association of autonomic dysfunction with SBI in AF patients. ...

FRONTIERS MEDIA SA2021

Reprogramming G Protein-Coupled Receptor Structure, Function And Signaling By Computational Design

Dániel Kéri

G protein-coupled receptors (GPCRs) are 7-transmembrane alpha-helical integral membrane proteins on which cells heavily rely to receive information regarding their external environment. These receptors are able to transfer information to intracellular down ...

EPFL2021

An intergrid transfer operator using radial basis functions with application to cardiac electromechanics

Alfio Quarteroni

In the framework of efficient partitioned numerical schemes for simulating multiphysics PDE problems, we propose using intergrid transfer operators based on radial basis functions to accurately exchange information among different PDEs defined in the same ...

SPRINGER2020

A mathematical model of the human heart

Alfio Quarteroni

In this paper, we present a mathematical model able to simulate the cardiac function. We first describe the basic physical principles behind the mathematical equations, then we illustrate a few examples of application to problems of clinical relevance. ...

PENSIERO SCIENTIFICO EDITOR2020

Active Force Generation in Cardiac Muscle Cells: Mathematical Modeling and Numerical Simulation of the Actin-Myosin Interaction

Alfio Quarteroni, Francesco Regazzoni, Luca Dede'

Cardiac in silico numerical simulations are based on mathematical models describing the physical processes involved in the heart function. In this review paper, we critically survey biophysically-detailed mathematical models describing the subcellular mech ...

SPRINGER SINGAPORE PTE LTD2021

Increasing heart vascularisation after myocardial infarction using brain natriuretic peptide stimulation of endothelial and WT1(+) epicardial cells

Na Li, Alexia Laurie Carboni

Brain natriuretic peptide (BNP) treatment increases heart function and decreases heart dilation after myocardial infarction (MI). Here, we investigated whether part of the cardioprotective effect of BNP in infarcted hearts related to improved neovascularis ...

2020

Investigating the variability of cardiac pulse artifacts across heartbeats in simultaneous EEG-fMRI recordings: A 7T study

Rolf Gruetter, João Pedro Forjaco Jorge, Lucie Bréchet

Electroencephalography (EEG) recordings performed in magnetic resonance imaging (MRI) scanners are affected by complex artifacts caused by heart function, often termed pulse artifacts (PAs). PAs can strongly compromise EEG data quality, and remain an open ...

2019

Analysis of photosensor frontends for biomedical applications: a focus on noise

Paul Stanislas Gosselin

Photosensing has proven to be highly useful in biomedical research and medical care. Being able to detect and quantify the light emitted by fluorescent or bioluminescent reporters has significantly participated in the development of new cancer treatments a ...

EPFL2019

A monolithic algorithm for the simulation of cardiac electromechanics in the human left ventricle

Alfio Quarteroni, Luca Dede', Antonello Gerbi

In this paper, we propose a monolithic algorithm for the numerical solution of the electromechanics model of the left ventricle in the human heart. Our coupled model integrates the monodomain equation with the Bueno-Orovio minimal model for electrophysiolo ...

2018