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Publications associées (5)

Multi-unit activity and high-gamma patterns dissociate in the seizure onset zone during focal to bilateral tonic-clonic seizures

Objectives To track multi-unit activity (MUA) using hybrid Behnke–Fried electrodes continuously throughout human seizures, and to characterize how both neuronal firing and high-gamma (HG) changes over the ictal course, within versus outside the seizure-onset zone (SOZ), and by seizure severity. Methods We analyzed 32 seizures - 9 focal preserved consciousness (FPC), 17 focal impaired consciousness (FIC), 6 focal-to-bilateral tonic–clonic (FBTC) - from 8 patients implanted with Behnke–Fried hybrid depth elec

Cold Spring Harbor Laboratory2025

The dynamical response properties of neocortical neurons to temporally modulated noisy inputs in vitro

Michele Giugliano

Cortical neurons are often classified by current-frequency relationship. Such a static description is inadequate to interpret neuronal responses to time-varying stimuli. Theoretical studies suggested that single-cell dynamical response properties are neces ...

Oxford University Press2008

High performance low-firing temperature thick-film pressure sensors on steel

Thomas Maeder, Peter Ryser, Giancarlo Corradini, Niklaus Johner

Performance of piezoresistive thick-film pressure sensors on steel substrates is hindered by the high required firing temperatures of the layers, which cause degradation of the substrate mechanical properties. Special steels or alloys that are relatively unaffected by these temperatures are available, but their cost is very high. A much more promising alternative is the reduction of the thick-film firing temperature, in order to allow application of the standard high-strength steels used in thin-film cells.

2007

Generalized Bienenstock-Cooper-Munro rule for spiking neurons that maximizes information transmission

Wulfram Gerstner, Jean-Pascal Théodor Pfister

Maximization of information transmission by a spiking-neuron model predicts changes of synaptic connections that depend on timing of pre- and postsynaptic spikes and on the postsynaptic membrane potential. Under the assumption of Poisson firing statistics, the synaptic update rule exhibits all of the features of the Bienenstock-Cooper-Munro rule, in particular, regimes of synaptic potentiation and depression separated by a sliding threshold. Moreover, the learning rule is also applicable to the more realist

2005

Coding properties of spiking neurons: reverse- and cross-correlations

Wulfram Gerstner

What is the meaning' of a single spike? Spike-triggered averaging (reverse correlations') yields the typical input just before a spike. Similarly, cross-correlations describe the probability of firing an output spike given (one additional) presynaptic input spike. In this paper we analytically calculate reverse and cross-correlations for a spiking neuron model with escape noise. The influence of neuronal parameters (such as the membrane time constant, the noise level, and the mean firing rate) on the form

Elsevier2001

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Publications associées (5)

Multi-unit activity and high-gamma patterns dissociate in the seizure onset zone during focal to bilateral tonic-clonic seizures

Cold Spring Harbor Laboratory2025