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Publications associées (29)

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A coupled 3D-1D numerical monodomain solver for cardiac electrical activation in the myocardium with detailed Purkinje network

Alfio Quarteroni, Christian Vergara, Toni Mikael Lassila

We present a model for the electrophysiology in the heart to handle the electrical propagation through the Purkinje system and in the myocardium, with two-way coupling at the Purkinje-muscle junctions. In both the subproblems the monodomain model is consid ...

Elsevier2016

Systems and methods for moving and circulating fluid to treat alzheimer's disease

A system for the treatment of Alzheimer's disease is provided by moving cerebrospinal fluid containing particles know to contribute to onset of Alzheimer's disease from a source of cerebrospinal fluid to the stomach or bladder, where the particles are safe ...

2016

Brain system for mental orientation in space, time, and person

Olaf Blanke, Roy Salomon

Orientation is a fundamental mental function that processes the relations between the behaving self to space (places), time (events), and person (people). Behavioral and neuroimaging studies have hinted at interrelations between processing of these three d ...

Natl Acad Sciences2015

Modelling blood flows in the heart: extended Nitsche's method for the treatment of the valves as generalized boundary conditions

Alfio Quarteroni, Luca Dede', Anna Tagliabue

We investigate the blood flow inside idealized left ventricles with prescribed wall movement by defining a formulation of boundary conditions for the Navier-Stokes equations accounting for the valves. Specifically, we consider an extended Nitsche’s method ...

CMBE, Zeta Computational Resources Ltd.2015

Connectomics across development : towards mapping brain structure from birth to childhood

Elda Fischi Gomez

The brain is probably the most complex system of the human body, composed of numerous neural units interconnected at dierent scales. This highly structured architecture provides the ability to communicate, synthesize information and perform the analytical ...

EPFL2015

Evaluation of automatic neonatal brain segmentation algorithms: The NeoBrainS12 challenge

Elda Fischi Gomez

A number of algorithms for brain segmentation in preterm born infants have been published, but a reliable comparison of their performance is lacking. The NeoBrainS12 study (http://neobrains12.isi.uu.nl), providing three different image sets of preterm born ...

Elsevier Science Bv2015

Red and NIR light dosimetry in the human deep brain

Georges Wagnières, Matthieu Philippe Emmanuel Zellweger, Blaise Lovisa

Photobiomodulation (PBM) appears promising to treat the hallmarks of Parkinson's Disease (PD) in cellular or animal models. We measured light propagation in different areas of PD-relevant deep brain tissue during transcranial, transsphenoidal illumination ...

Iop Publishing Ltd2015

Proteomics of Cerebrospinal Fluid: Throughput and Robustness Using a Scalable Automated Analysis Pipeline for Biomarker Discovery

Loïc Dayon

Cerebrospinal fluid (CSF) is a body fluid of high clinical relevance and an important source of potential biomarkers for brain-associated damages, such as traumatic brain injury and stroke, and for brain diseases, such as Alzheimer's and Parkinson's. Herei ...

Amer Chemical Soc2015

Characterization of the Discrepancies Between Four-Dimensional Phase-Contrast Magnetic Resonance Imaging and In-Silico Simulations of Cerebrospinal Fluid Dynamics

The purpose of the present study was to compare subject-specific magnetic resonance imaging (MRI)-based computational fluid dynamics (CFD) simulations with time-resolved three-directional (3D) velocity-encoded phase-contrast MRI (4D PCMRI) measurements of ...

American Society of Mechanical Engineers2015