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Publications associées (29)

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An ecological and digital epidemiology analysis on the role of human behavior on the 2014 Chikungunya outbreak in Martinique

Marcel Salathé

Understanding the spatio-temporal dynamics of endemic infections is of critical importance for a deeper understanding of pathogen transmission, and for the design of more efficient public health strategies. However, very few studies in this domain have foc ...

Nature Research2017

Modeling Key Drivers of Cholera Transmission Dynamics Provides New Perspectives for Parasitology

Andrea Rinaldo, Enrico Bertuzzo, Melanie Blokesch, Lorenzo Mari

Hydroclimatological and anthropogenic factors are key drivers of waterborne disease transmission. Information on human settlements and host mobility on waterways along which pathogens and hosts disperse, and relevant hydroclimatological processes, can be a ...

2017

Statistical physics of vaccination

Marcel Salathé

Historically, infectious diseases caused considerable damage to human societies, and they continue to do so today. To help reduce their impact, mathematical models of disease transmission have been studied to help understand disease dynamics and inform pre ...

Elsevier Science Bv2016

Mobile phone data highlights the role of mass gatherings in the spreading of cholera outbreaks

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Flavio Finger

The spatiotemporal evolution of human mobility and the related fluctuations of population density are known to be key drivers of the dynamics of infectious disease outbreaks. These factors are particularly relevant in the case of mass gatherings, which may ...

National Academy of Sciences2016

Observer Placement for Source Localization: the Effect of Budgets and Transmission Variance

Patrick Thiran, Brunella Marta Spinelli, Laura Elisa Celis

When an epidemic spreads in a network, a key question is where was its source, i.e., the node that started the epidemic. If we know the time at which various nodes were infected, we can attempt to use this information in order to identify the source. Howev ...

2016

Engineered cell instructive matrices for fetal membrane healing

Iatrogenic preterm prelabour rupture of fetal membranes (iPPROM) occurs in 6-45% of the cases after fetoscopic procedures, posing a significant threat to fetal survival and well-being. The number of diagnostic and therapeutic prenatal interventions availab ...

Elsevier Sci Ltd2015

A Theoretical Analysis of the Geography of Schistosomiasis in Burkina Faso Highlights the Roles of Human Mobility and Water Resources Development in Disease Transmission

Andrea Rinaldo, Enrico Bertuzzo, Lorenzo Mari, Natalie Claire Ceperley, Francisco Javier Perez Saez, Theophile Mande, Jean-Marc Fröhlich

We study the geography of schistosomiasis across Burkina Faso by means of a spatially explicit model of water-based disease dynamics. The model quantitatively addresses the geographic stratification of disease burden in a novel framework by explicitly acco ...

Public Library of Science2015

Disentangling human tolerance and resistance against HIV

Jacques Fellay, Paul Jack Mc Laren

In ecology, "disease tolerance" is defined as an evolutionary strategy of hosts against pathogens, characterized by reduced or absent pathogenesis despite high pathogen load. To our knowledge, tolerance has to date not been quantified and disentangled from ...

Public Library Science2014

Rapid Intrahost Evolution of Human Cytomegalovirus Is Shaped by Demography and Positive Selection

Jeffrey David Jensen

Populations of human cytomegalovirus (HCMV), a large DNA virus, are highly polymorphic in patient samples, which may allow for rapid evolution within human hosts. To understand HCMV evolution, longitudinally sampled genomic populations from the urine and p ...

Public Library of Science2013