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Publications associées (28)

Tunable biocomposite films fabricated using cellulose nanocrystals and additives for food packaging

Wenjing Sun

Cellulose nanocrystals (CNCs) are considered a prospective packaging material to partially replace petroleumbased plastics attributed to their renewability, sustainability, biodegradability, and desirable attributes including transparency, oxygen, and oil ...

ELSEVIER SCI LTD2023

Surface and bulk stresses drive morphological changes in fibrous microtissues

Mahmut Selman Sakar, Erik Mailand, Nikolaos Bouklas

Engineered fibrous tissues consisting of cells encapsulated within collagen gels are widely used three-dimensional (3D) in vitro models of morphogenesis and wound healing. While cell-mediated matrix remodeling that occurs within these scaffolds has been ex ...

2019

Podosomes, But not the Maturation status, Determine the Protease-Dependent 3D Migration in human Dendritic cells

Romain Guiet

Dendritic cells (DC) are professional Antigen-Presenting Cells scattered throughout antigen-exposed tissues and draining lymph nodes, and survey the body for pathogens. Their ability to migrate through tissues, a 3D environment, is essential for an effecti ...

2018

Synthesis strategies to extend the variety of alginate-based hybrid hydrogels for cell microencapsulation

Jutta Christine Wandrey, Sandrine Gerber, Solène Marcelle Françoise Marie Passemard, François Rémi Pierre Noverraz, Luca Szabó

The production of hydrogel microspheres (MS) for cell immobilization, maintaining the favorable properties of alginate gels but presenting enhanced performance in terms of in vivo durability and physical properties, is desirable to extend the therapeutic p ...

American Chemical Society2017

Predicting the yield stress of paraffin-wax suspensions

Paul Bowen

An empirical modification of the Yodel model was developed for the prediction of the yield stress of concentrated, particulate, paraffin-wax suspensions, with a solids loading in the range of 47-57 vol.%, used in the low-pressure injection moulding (LPIM). ...

Elsevier2016

Ophthalmic contact lens with a compressible affinity matrix

Philippe Renaud, Thomas Michael Braschler, Amélie Barbara Hildegarde Béduer

The invention relates to a contact lens for use in the treatment of ocular inflammatory pathologies. The contact lens comprises a soft porous material coupled, in certain embodiments, with detoxifying agents. Said material and/or agents contact and neutral ...

2016

Bio-engineered collagen-fibrin scaffolds for enhancing urological tissue regeneration

Elif Vardar

Urological tissue engineering offers alternative solutions for congenital and acquired diseases of the urinary tract, which may require reconstructive surgery. It evolves to overcome complications, which might be encountered after surgery. Therefore, tissu ...

EPFL2015

The Nano-Scale Mechanical Properties of the Extracellular Matrix Regulate Dermal Fibroblast Function

Boris Hinz, Jean-Jacques Meister, Josiane Angèle Charlotte Smith-Clerc, Lara Buscemi Estefanell

Changes in the mechanical properties of dermis occur during skin aging or tissue remodeling and affect the activity of resident fibroblasts. With the aim to establish elastic culture substrates that reproduce the variable softness of dermis, we determined ...

Nature Publishing Group2014

Influence Of Processing And Storage On The Shear Thickening Properties Of Highly Concentrated Monodisperse Silica Particles In Polyethylene Glycol

Jan-Anders Edvin Maansson, Véronique Michaud, Mathieu Soutrenon

The shear thickening behavior of concentrated suspensions can be exploited to dissipate energy during impact or shear loading. To preserve the consistency of the thickening behavior in practical applications, particle concentration, and dispersion should b ...

Kerschensteiner Verlag Gmbh2013

The Mechanical Environment Modulates Intracellular Calcium Oscillation Activities of Myofibroblasts

Boris Hinz, Adriano Garonna, Lysianne Follonier Castella

Myofibroblast contraction is fundamental in the excessive tissue remodeling that is characteristic of fibrotic tissue contractures. Tissue remodeling during development of fibrosis leads to gradually increasing stiffness of the extracellular matrix. We pro ...

Public Library Science2013

Shear Thickening Fluid Impregnated Foam Composites for Vibration Control and Impact Protection

Mathieu Soutrenon

Highly concentrated suspensions of silica particles present shear thickening properties, shifting from a low to a high viscosity state, instantly and reversibly at a critical shear rate. Their viscosity increases by up to 3 orders of magnitude, changing fr ...

EPFL2013

Structural damping using encapsulated Shear Thickening Fluids

Véronique Michaud, Mathieu Soutrenon

Smart structures with tunable damping and stiffness characteristics are of high interest to aerospace applications, but often require an external power source to be activated. This can be avoided by using highly concentrated silica suspensions, which exhib ...

Spie-Int Soc Optical Engineering, Po Box 10, Bellingham, Wa 98227-0010 Usa2012

Dam Break of Newtonian Fluids and Granular Suspensions : Internal Dynamics Measurements

Nicolas Andreini

The objective of this thesis was to increase our understanding of two-phase geophysical flows (e.g. debris flows) by providing velocity profiles in idealized laboratory avalanches. To that end, we developed a new experimental platform made up of an incline ...

EPFL2012

Link between Alginate Reaction Front Propagation and General Reaction Diffusion Theory

Jürgen Brugger, Philippe Renaud, Thomas Michael Braschler, Ana Valero, Kristopher Pataky, Ludovica Colella

We provide a common theoretical framework reuniting specific models for the Ca2+-alginate system and general reaction diffusion theory along with experimental validation on a microfluidic chip. As a starting point, we use a set of nonlinear, partial differ ...

2011

Hydrogels for Urinary Tract Tissue Engineering

Several urinary tract disorders, such as hypospadias or bladder cancer, require reconstructive surgery to preserve the patient's quality of life and at times even save their life. The current available surgical treatments, involving grafts from other tissu ...

EPFL2011

In vivo study of an injectable poly(acrylonitrile)-based hydrogel paste as a bulking agent for the treatment of urinary incontinence

Jeffrey Alan Hubbell, Peter Frey

Urinary incontinence can be treated by endoscopic injection of bulking agents, however, no optimal therapeutic effect has been achieved upon this treatment yet. In the present study, the development of a injectable poly(acrylonitrile) hydrogel paste is des ...

Elsevier2010

Alginate-Poly(ethylene glycol) Hybrid Microspheres with Adjustable Physical Properties

Jutta Christine Wandrey, Redouan Mahou

A one-step extrusion process under physiological conditions yielded calcium alginate-poly-(ethylene glycol) hybrid microspheres (Alg-PEG-M), for which the physical properties were adjustable by the macromolecular characteristics of the components, their co ...

American Chemical Society2010

Fluidic microstructuring of alginate hydrogels for the single cell niche

Jürgen Brugger, Philippe Renaud, Thomas Michael Braschler, Ana Valero, Kristopher Pataky, Ludovica Colella

Controlling alginate gel formation by diffusion of Ca2+ ions through a filter barrier, a layer-by-layer deposition technique with resolution on the size scale of a single cell is presented. It offers the possibility of exposing cells under biocompatible co ...

Royal Society of Chemistry2010

Hypoxia Impairs Skin Myofibroblast Differentiation and Function

Boris Hinz

Ischemic wounds are characterized by oxygen levels lower than that of healthy skin ( hypoxia) and poor healing. To better understand the pathophysiology of impaired wound healing, we investigated how switching from high ( 21%) to low ( 2%) oxygen levels di ...

Nature Publishing Group2010

Analyzing halftone dot blurring by extended spectral prediction models

Roger Hersch, Mathieu Hébert

Spectral prediction models for halftone prints generally assume homogeneously thick and sharply edged ink dots, i.e., bilevel halftones. In real prints, the ink thickness often decreases at the boundaries of the ink dots, thereby forming continuous-level h ...

2010