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Concept

Rhodopsine

Publications associées (25)

Mechanisms of Apoptosis in Retinitis Pigmentosa

Mutations in humans are associated with several forms of inherited retinal dystrophies, such as Retinitis Pigmentosa which lead to retinal cell death and irreversible loss of vision. Genes involved in affected patients mainly encode proteins related to vis ...

2009

Bax-Induced Apoptosis in Leber's Congenital Amaurosis: A Dual Role in Rod and Cone Degeneration

Pathogenesis in the Rpe65(-/-) mouse model of Leber's congenital amaurosis (LCA) is characterized by a slow and progressive degeneration of the rod photoreceptors. On the opposite, cones degenerate rapidly at early ages. Retinal degeneration in Rpe65(-/-) ...

Public Library of Science2009

Colloidal characterization and thermodynamic stability of binary eye lens protein mixtures

Giuseppe Foffi, Nicolas Dorsaz

We present a study of binary mixtures of eye lens crystallin proteins. A coarse-grained model of aqueous aand γ-crystallin mixtures based on molecular dynamics simulations and SANS experiments is proposed. Thermodynamic perturbation theory is implemented t ...

2009

An artificial molecular switch that mimics the visual pigment and completes its photocycle in picoseconds

Majed Chergui, Andrea Cannizzo, Stefan Haacke

Single mols. that act as light-energy transducers (e.g., converting the energy of a photon into at.-level mech. motion) are examples of minimal mol. devices. Here, we focus on a mol. switch designed by merging a conformationally locked diarylidene skeleton ...

National Academy of Sciences2008

Digital Camera Workflow for High Dynamic Range Images Using a Model of Retinal Processing

Sabine Süsstrunk, Laurence Meylan

We propose a complete digital camera workflow to capture and render high dynamic range (HDR) static scenes, from RAW sensor data to an output- referred encoded image. In traditional digital camera processing, demosaicing is one of the first operations done ...

2008