The serine proteases CAP1/Prss8 and CAP3/St14 are identified as ENaC channel-activating proteases in vitro, highly suggesting that they are required for proteolytic activation of ENaC in vivo. The present study tested whether CAP3/St14 is relevant for rena ...
Hydraulic fractures are driven by an internal fluid pressure exceeding the minimum compressive stress, propagating in a direction perpendicular to the latter. This class of tensile fractures has gained interest over the last fifty years due to the developm ...
Depending on the type of fracture propagation regime when the injection stops, the closure of the fracture may occur exactly after the injection ceases, in the case where the fracturing process is dominated by fracture energy, or the fracture propagate for ...
Background: The associations among cortisol levels, body water status, and acute mountain sickness (AMS) remain unclear. We investigated associations between AMS prevalence and severity with resting saliva cortisol levels at low altitude (LA) and high alti ...
The kidney is a key organ in the maintenance of ion and fluid homeostasis and specific transport systems localized along the nephron guarantee this function. Due to its large functional heterogeneity, experiments on the whole organ level cannot be easily p ...