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Concept

Calcium pyrophosphate dihydrate crystal deposition disease

Publications associées (14)

Morphological assessment of cartilage and osteoarthritis in clinical practice and research: Intermediate-weighted fat-suppressed sequences and beyond

Tom Hilbert

Magnetic resonance imaging (MRI) is widely regarded as the primary modality for the morphological assessment of cartilage and all other joint tissues involved in osteoarthritis. 2D fast spin echo fat-suppressed intermediate-weighted (FSE FS IW) sequences w ...

SPRINGER2023

Diverse parameters of ambulatory knee moments differ with medial knee osteoarthritis severity and are combinable into a severity index

Julien Favre, Brigitte Jolles-Haeberli

Objective: To characterize ambulatory knee moments with respect to medial knee osteoarthritis (OA) severity comprehensively and to assess the possibility of developing a severity index combining knee moment parameters. ...

FRONTIERS MEDIA SA2023

Decreasing the ambulatory knee adduction moment without increasing the knee flexion moment individually through modifications in footprint parameters: A feasibility study for a dual kinetic change in healthy subjects

Julien Favre, Brigitte Jolles-Haeberli

Gait retraining is gaining in interest to reduce loading associated to knee osteoarthritis (OA) progression. So far, interventions focused on reducing the peak knee adduction moment (pKAM) and it remains unclear if this can be done individually without inc ...

ELSEVIER SCI LTD2020

Gait features for discriminating between mobility-limiting musculoskeletal disorders: Lumbar spinal stenosis and knee osteoarthritis

Wei Zhang

Background: Functional ambulation limitations are features of lumbar spinal stenosis (LSS) and knee osteoarthritis (OA). With numerous validated walking assessment protocols and a vast number of spatiotemporal gait parameters available from sensor-based as ...

ELSEVIER IRELAND LTD2020

Modifying Stride Length in Isolation and in Combination With Foot Progression Angle and Step Width Can Improve Knee Kinetics Related to Osteoarthritis; A Preliminary Study in Healthy Subjects

Brigitte Jolles-Haeberli

The purpose of this study was to determine the effects of modifying stride length (SL) on knee adduction and flexion moments, two markers of knee loading associated with medial-compartment knee osteoarthritis (OA) progression. This study also tested if SL ...

2020

Relationships between cartilage thickness and subchondral bone mineral density in non-osteoarthritic and severely osteoarthritic knees: In vivo concomitant 3D analysis using CT arthrography

Julien Favre, Brigitte Jolles-Haeberli

Objective: To test whether subchondral bone mineral density (sBMD) and cartilage thickness (CTh) of femoral condyles are correlated in knees without and with severe medial femorotibial osteoarthritis (OA), using a subregional analysis with computerized tom ...

ELSEVIER SCI LTD2019

Tailoring the Mechanical Properties of Tissue Engineering Scaffolds made from Decellularized Cartilage

Jens Antons

Due to its limited regeneration capacity, articular cartilage defects are considered a frequent clinical problem. Initial cartilage defects, if left untreated, will progress in severity over time and can eventually lead to degenerative joint diseases such ...

EPFL2019

Modeling knee osteoarthritis pathophysiology using an integrated joint system (IJS): a systematic review of relationships among cartilage thickness, gait mechanics, and subchondral bone mineral density

Julien Favre, Brigitte Jolles-Haeberli

Objective: To introduce an integrated joint system (IJS) model of joint health and osteoarthritis (OA) pathophysiology through a systematic review of the cross-sectional relationships among three knee properties (cartilage thickness, gait mechanics, and su ...

ELSEVIER SCI LTD2018

Quantitative regional and sub-regional analysis of femoral and tibial subchondral bone mineral density (sBMD) using computed tomography (CT): comparison of non-osteoarthritic (OA) and severe OA knees

Julien Favre, Brigitte Jolles-Haeberli

Objective: This study aimed to compare subchondral bone mineral density (sBMD) between non-radiographic osteoarthritic (OA) and medial femorotibial OA knees, using computed tomography (CT). Design: CT exams from 16 non-radiographic OA (KL grade < 2) and 16 ...

Elsevier Sci Ltd2017

Micromotion and fluid flow around cementless femoral components in total hip arthroplasty

Valérie Hélène Emilie Malfroy Camine

Cementless total hip arthroplasty is a highly successful and reliable procedure to restore joint function and reduce pain in patients with severe osteoarthritis. Nevertheless, despite the technical advances over the last decades in the development of cemen ...

EPFL2016

The measurement of biomechanical properties of porcine articular cartilage using atomic force microscopy

Nico de Rooij, Terunobu Akiyama

We have recently demonstrated that indentation-type atomic force microscopy (IT-AFM) is capable of detecting early onset osteoarthritis (OA) (Stolz, 2009). This study was based on biopsies, using a desk-top commercial atomic force microscope (AFM). However ...

Japan Society of Histological Documentation / International Society of Histology and Cytology2011

Identification and Functional Response of "Interstitial Cells of Cajal"-like Cells from Rat Mesenteric Artery

Aurélie Formey de Saint Louvent

This thesis is a contribution to the field of interstitial cells of Cajal-like cells (ICC-LCs) in the vasculature. Indeed, cells with irregular shapes and numerous long thin filaments, morphologically similar to the gastrointestinal ICCs, have been observe ...

EPFL2011

Peptide ligands for targeting and retention of nanoparticles and protein therapeutics in articular cartilage

Osteoarthritis (OA) is one of the most common causes of pain and disability. Currently, non-surgical treatment is limited to analgesic and anti-inflammatory drugs, which are not capable of either modifying the disease process or regenerate damaged parts in ...

EPFL2009

Outcome evaluation in shoulder surgery using 3D kinematics sensors

Kamiar Aminian, Alain Farron, Brian Coley

A new method of scoring systems for the functional assessment of the shoulder is presented. 3D accelerometers and gyroscopes attached on the humerus were used to differentiate a healthy from a painful shoulder. The method was first tested on 10 healthy vol ...

2007