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Concept

Compteur Coulter

Publications associées (25)

Micropositioning and microscopic observation of individual picoliter-sized containers within SU-8 microchannels

Jürgen Brugger, Horst Arthur Vogel, Christoph Schreiter

We describe the fabrication and application of a bioanalytical chip, made of SU-8 photoresist, comprising integrated, high aspect-ratio microfluidic channels, suitable to manipulate and investigate vesicles, cell fragments and biological cells. A central m ...

2007

Analytical expression for electric filed between two facing strip electrodes in microchannels

Philippe Renaud, Olof Pontus Linderholm, Urban Seger

An analytical solution is presented for the electric field between two facing strip electrodes situated in a microchannel, as frequently used in impedance cytometry applications. The measured change in resistance as induced by a 5 mm bead moving through th ...

2006

Impedance spectroscopy flow cytometry: On-chip label-free cell differentiation

Philippe Renaud, Shady Didier Gawad, Karen Cheung

Background: The microfabricated impedance spectroscopy flow cytometer used in this study permits rapid dielectric characterization of a cell population with a simple microfluidic channel. Impedance measurements over a wide frequency range provide informati ...

2005

Flexible polyimide probes with microelectrodes and embedded microfluidic channels for simultaneous drug delivery and multi-channel monitoring of bioelectric activity

Philippe Renaud, Arnaud Bertsch, Stefan Metz

The study of intracellular communication requires devices that can not only monitor the bioelectric activity, but also control and observe the biochemical environment at the cellular level. This paper reports on the development and characterisation of impl ...

Elsevier2004

Dielectric spectroscopy in a micromachined flow cytometer: theoretical and practical considerations

Philippe Renaud, Arnaud Bertsch, Shady Didier Gawad, Urban Seger, Karen Cheung

We propose a model to determine the influence of different cell properties, such as size, membrane capacitance and cytoplasm conductivity, on the impedance spectrum as measured in a microfabricated cytometer. A dielectric sphere of equivalent complex permi ...

2004