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Concept

Fœtus humain

Publications associées (16)

SELF-SUPERVISED ISOTROPIC SUPERRESOLUTION FETAL BRAIN MRI

Michaël Unser, Meritxell Bach Cuadra

Superresolution T2-weighted fetal-brain magnetic-resonance imaging (FBMRI) traditionally relies on the availability of several orthogonal low-resolution series of 2-dimensional thick slices (volumes). In practice, only a few low-resolution volumes are acqu ...

IEEE2023

Prenatal auditory experience and its sequelae

Lukas Vogelsang

Towards the end of the second trimester of gestation, a human fetus is able to register environmental sounds. This in utero auditory experience is characterized by comprising strongly low-pass-filtered versions of sounds from the external world. Here, we p ...

2022

Slice Estimation in Diffusion MRI of Neonatal and Fetal Brains in Image and Spherical Harmonics Domains Using Autoencoders

Meritxell Bach Cuadra, Gabriel Girard, Erick Jorge Canales Rodriguez, Thomas Yu

Diffusion MRI (dMRI) of the developing brain can provide valuable insights into the white matter development. However, slice thickness in fetal dMRI is typically high (i.e., 3-5 mm) to freeze the in-plane motion, which reduces the sensitivity of the dMRI s ...

SPRINGER INTERNATIONAL PUBLISHING AG2022

An automatic multi-tissue human fetal brain segmentation benchmark using the Fetal Tissue Annotation Dataset

Meritxell Bach Cuadra, Asim Iqbal

It is critical to quantitatively analyse the developing human fetal brain in order to fully understand neurodevelopment in both normal fetuses and those with congenital disorders. To facilitate this analysis, automatic multi-tissue fetal brain segmentation ...

NATURE RESEARCH2021

Fighting preterm birth with novel surgical tools and biomaterials engineering

Yannick Robert Devaud

With advances in fetal diagnosis and therapy, fetoscopy has become a good option to treat a series of life threatening diseases like twin-to-twin transfusion syndrome or severe congenital diaphragmatic hernia. The efficacy of fetoscopy for those types of d ...

EPFL2017

Transcriptomic regulations in oligodendroglial and microglial cells related to brain damage following fetal growth restriction

Yohan Van de Looij, Maxime Olivier Baud

Fetal growth restriction (FGR) is a major complication of human pregnancy, frequently resulting from placental vascular diseases and prenatal malnutrition, and is associated with adverse neurocognitive outcomes throughout life. However, the mechanisms link ...

Wiley-Blackwell2016

Engineered cell instructive matrices for fetal membrane healing

Iatrogenic preterm prelabour rupture of fetal membranes (iPPROM) occurs in 6-45% of the cases after fetoscopic procedures, posing a significant threat to fetal survival and well-being. The number of diagnostic and therapeutic prenatal interventions availab ...

Elsevier Sci Ltd2015

Tissue engineering for prenatal applications

Anna-Sofia Johanna Kiveliö

Fetal therapies have become available for a restricted number of life-threatening clinical conditions. Harnessing tissue engineering for prenatal applications has not been widely pursued even though isolating cells from fetal and extraembryonic tissues has ...

EPFL2015

Connectomics across development : towards mapping brain structure from birth to childhood

Elda Fischi Gomez

The brain is probably the most complex system of the human body, composed of numerous neural units interconnected at dierent scales. This highly structured architecture provides the ability to communicate, synthesize information and perform the analytical ...

EPFL2015

Evaluation and Comparison of Current Fetal Ultrasound Image Segmentation Methods for Biometric Measurements: A Grand Challenge

Meritxell Bach Cuadra, Xavier Bresson, Anca-Ramona Ciurte

This paper presents the evaluation results of the methods submitted to Challenge US: Biometric Measurements from Fetal Ultrasound Images, a segmentation challenge held at the IEEE International Symposium on Biomedical Imaging 2012. The challenge was set to ...

Institute of Electrical and Electronics Engineers2014

Prenatally engineered autologous amniotic fluid stem cell-based heart valves in the fetal circulation

Peter Modregger

Prenatal heart valve interventions aiming at the early and systematic correction of congenital cardiac malformations represent a promising treatment option in maternal-fetal care. However, definite fetal valve replacements require growing implants adaptive ...

2012

High-field diffusion tensor imaging characterization of cerebral white matter injury in lipopolysaccharide-exposed fetal sheep

Yohan Van de Looij, François Lazeyras

BACKGROUND: In gyrencephalic species such as sheep, precise anatomical and microstructural characterization of the consequences of fetal inflammation remains scarce. The goal of this study was to characterize changes in white matter (WM) structure using ad ...

Lippincott, Williams & Wilkins2012

An assessment of ductus venosus tapering and wave transmission from the fetal heart

Nikolaos Stergiopoulos

Pressure and flow pulsations in the fetal heart propagate through the precordial vein and the ductus venosus (DV) but are normally not transmitted into the umbilical vein (UV). Pulsations in the umbilical vein do occur, however, in early pregnancy and in p ...

2009

Bioengineering of foetal membrane repair

Preterm premature rupture of the foetal membranes (fruber vorzeitiger Blasensprung) has remained a devastating complication of pregnancy with very high risk of pregnancy loss. Several methods of sealing spontaneously ruptured membranes to stop amniotic flu ...

2008

Notch signaling in hematopoiesis and lymphopoiesis: lessons from Drosophila

Freddy Radtke

The evolutionarily conserved Notch signaling pathway regulates a broad spectrum of cell fate decisions and differentiation processes during fetal and postnatal life. It is involved in embryonic organogenesis as well as in the maintenance of homeostasis of ...

2005

Biocompatibility of bioresorbable poly(L-lactic acid) composite scaffolds obtained by supercritical gas foaming with human fetal bone cells

Jan-Anders Edvin Maansson, Dominique Pioletti, Pierre-Etienne Bourban, Boris Hinz, Laurence Marcelle Monique Rivier

The aim of this investigation was to test the biocompatibility of three-dimensional bioresorbable foams made of poly(L-lactic acid) (PLA), alone or filled with hydroxyapatite (HA) or beta-tricalcium phosphate (beta-TCP), with human primary osteoblasts, usi ...

2005