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Publications associées (13)

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Intrafascicular electrode implant

Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini

An implantable device for intrafascicular stimulation and/or sensing of a peripheral nerve, including a blocking element adapted for wrapping a nerve, comprising an access point and an exit point, and an electrode adapted to traverse the blocking element v ...

2018

Devices, systems and methods for dispensing and analysing particles

Philippe Renaud, Yann Barrandon, David Vincent Bonzon, Jean-Baptiste Bureau

The present invention relates to a pipette tip comprising a thin holed membrane at its distal end, which is designed to be adapted with a system comprising at least an impedance analyser and a fluidic actuator to perform the dispensing and analysis of part ...

2016

Time course of bone screw fixation following a local delivery of zoledronate in a rat femoral model – a micro-finite element analysis

Dominique Pioletti, Alexandre Terrier, Ulrike Kettenberger, Adeliya Latypova

A good fixation of osteosynthesis implants is crucial for a successful bone healing but often difficult to achieve in osteoporotic patients. One possible solution to this issue is the local delivery of bisphosphonates in direct proximity to the implants, A ...

Elsevier2015

Development of an in situ controllable polymerization tool and process for hydrogel used to replace nucleus pulposus

Dominique Pioletti, Christophe Moser, Pierre-Etienne Bourban, Andreas Schmocker, Azadeh Khoushabi

Currently implants or tissue replacements are inserted either as a whole implant or by injecting a liquid which polymerizes to form a solid implant at the appropriate location. This is either highly invasive or not controllable. We developed a tool to perf ...

Spie-Int Soc Optical Engineering2015

Development of a Bisphosphonate Delivering Hydrogel for the Augmentation of Impaired Peri-Implant Bone

Ulrike Kettenberger

Osteoporosis is a major health problem in our aging society. This metabolic disease, which is characterized by a deterioration of the bone microarchitecture and a significant loss of bone mass, is affecting a rising number of mostly elderly patients. The m ...

EPFL2014

Adjustable fixation system for neurosurgical devices

Jean-Philippe Thiran, Rémi Charrier

The system comprises at least a support (5) to be attached to a patient by fixing means (4), said support having an outer thread (7), a first nut (9) with an inner thread (11 ) cooperating with said outer thread (7) and an anchor having a spherical bottom ...

2012

Ventricle Equilibrium Position in Healthy and Normal Pressure Hydrocephalus Brains Using an Analytical Model

Jean-Marie Drezet, Kamal Shahim

The driving force that causes enlargement of the ventricles remains unclear in case of normal pressure hydrocephalus (NPH). Both healthy and NPH brain conditions are characterized by a low transparenchymal pressure drop, typically 1 mm Hg. The present pape ...

2012

Robotic system for cervical spine surgery

Background In contemporary surgical clinical practice, spinal instability is often treated with mechanical stabilization techniques in order to protect the spinal cord and nerve roots. These techniques involve placing screws in defined regions of the verte ...

2012

Accurate Internal-External Rotation Measurement in Total Knee Prostheses: a magnetic solution

Kamiar Aminian, Arash Arami, Jenifer Cléa Miehlbradt

In this work we tackled the problem of accurate measurement of internal–external (IE) rotations in the prosthetic knee. We presented a magnetic measurement system to be implanted in the knee prostheses in order to measure IE without soft tissue artifacts. ...

Elsevier2012

In vivo assessment of local effects after application of bone screws delivering bisphosphonates into a compromised cancellous bone site

Dominique Pioletti, Alireza Roshan Ghias

Background: The primary stability of cancellous screw is difficult to obtain in bone of compromised quality and failure of screw fixation is common. To overcome this problem, it is proposed to locally deliver bisphosphonate from the screw An in vivo valida ...

Elsevier2011

Local delivery of bisphosphonate from coated orthopedic implants increases implants mechanical stability in osteoporotic rats

Dominique Pioletti, Randoald Müller, Bastian Peter

Patients with osteoporosis and joint disabilities represent a constant growing and challenging population to be treated in the musculoskeletal clinical field. Especially in the case of total hip arthroplasty, new solutions should be developed to compensate ...

2006

Calcium phosphate drug delivery system: influence of local zoledronate release on bone implant osteointegration

Dominique Pioletti, Bastian Peter

Despite total hip replacement (THR) gives generally satisfactory results, the quality of outcome in young patients is markedly decreased compared to the average THR outcome. For this population, pharmacological treatment with bisphosphonate would be benefi ...

2005

Radial elasticity of multiwalled carbon nanotubes

Harald Brune, Stephan Fedrigo, Ismaël Palaci, Christian Klinke

We report an experimental and a theoretical study of the radial elasticity of multiwalled carbon nanotubes as a function of external radius. We use atomic force microscopy and apply small indentation amplitudes in order to stay in the linear elasticity reg ...

2005