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Publications associées (21)

Proteomics reveals unique plasma signatures in constitutional thinness

Loïc Dayon, Jörg Hager, Nele Gheldof

Purpose Studying the plasma proteome of control versus constitutionally thin (CT) individuals, exposed to overfeeding, may give insights into weight-gain management, providing relevant information to the clinical entity of weight-gain resistant CT, and dis ...

WILEY-V C H VERLAG GMBH2022

Separating Algorithms From Questions and Causal Inference With Unmeasured Exposures: An Application to Birth Cohort Studies of Early Body Mass Index Rebound

Mats Julius Stensrud, Aaron Leor Sarvet

Observational studies reporting on adjusted associations between childhood body mass index (BMI; weight (kg)/height (m)(2)) rebound and subsequent cardiometabolic outcomes have often not paid explicit attention to causal inference, including definition of ...

2021

Turning negative into positives! Exploiting 'negative' results in Brain-Machine Interface (BMI) research

Ricardo Andres Chavarriaga Lozano, Camille Marie Jeunet

Results that do not confirm expectations are generally referred to as 'negative' results. While essential for scientific progress, they are too rarely reported in the literature - Brain-Machine Interface (BMI) research is no exception. This led us to organ ...

TAYLOR & FRANCIS LTD2019

Human biases in body measurement estimation

Robert West, Venkata Rama Kiran Garimella

Body measurements, including weight and height, are key indicators of health. Being able to visually assess body measurements reliably is a step towards increased awareness of overweight and obesity and is thus important for public health. Nevertheless it ...

2020

Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in healthy obese humans

Johan Auwerx, Richardus Houtkooper

Background: Nicotinamide riboside (NR) is an NAD(+) precursor that boosts cellular NAD(+) concentrations. Preclinical studies have shown profound metabolic health effects after NR supplementation. ...

OXFORD UNIV PRESS2020

The role of somatosensory feedback for brain-machine interfaces applications

Tiffany Corbet

Brain-machine interfaces (BMI) based on motor imagery (MI) have emerged as a promising approach to enhance motor skills and restore motor functions. However, the efficacy and efficiency of BMI systems remain limited. The current lack of usability can be ex ...

EPFL2019

Genome-wide gene-based analyses of weight loss interventions identify a potential role for NKX6.3 in metabolism

Patrick Descombes, Jörg Hager, Nele Gheldof, Hélène Ruffieux

Hundreds of genetic variants have been associated with Body Mass Index (BMI) through genome-wide association studies (GWAS) using observational cohorts. However, the genetic contribution to efficient weight loss in response to dietary intervention remains ...

Springer2019

Non-invasive, Brain-controlled Functional Electrical Stimulation for Locomotion Rehabilitation in Individuals with Paraplegia

Mohamed Bouri, Solaiman Shokur, Miguel Nicolelis

Spinal cord injury (SCI) impairs the flow of sensory and motor signals between the brain and the areas of the body located below the lesion level. Here, we describe a neurorehabilitation setup combining several approaches that were shown to have a positive ...

Nature Research2019

Inconsistent relationship between body weight/body mass index prior to total knee arthroplasty and the 12-year survival

Brigitte Jolles-Haeberli

Background: The primary hypothesis was that body weight (BW) and body mass index (BMI) significantly impact the long-term survival rate after implantation of a mobile bearing total knee arthroplasty (TKA). ...

ELSEVIER2019

Detecting overlapping spatial clusters of high sugar-sweetened beverage intake and high body mass index in a general population: a cross-sectional study

Stéphane Joost, Idris Guessous, David Nicolas De Ridder

Background: Evidence suggests that sugar-sweetened beverage (SSB) intake frequency is positively associated with the risk of obesity and diabetes. We aimed to identify populations and areas in high need for interventions to reduce SSB consumption using a f ...

2018

Quantifying the role of motor imagery in brain-machine interfaces

Olaf Blanke, Hannes Bleuler, Andrea Serino, Michela Bassolino, Silvia Marchesotti

Despite technical advances in brain machine interfaces (BMI), for as-yet unknown reasons the ability to control a BMI remains limited to a subset of users. We investigate whether individual differences in BMI control based on motor imagery (MI) are related ...

Nature Research2016

Persistent spatial clusters of high body mass index in a Swiss urban population as revealed by the 5-year GeoCoLaus longitudinal study

Stéphane Joost, Idris Guessous, Joël Chételat, Murielle Bochud, Solange Catherine Gaillard

OBJECTIVE Body mass index (BMI) may cluster in space among adults and be spatially dependent. Whether and how BMI clusters evolve over time in a population is currently unknown. We aimed to determine the spatial dependence of BMI and its 5-year evolution i ...

Bmj Publishing Group2016

Motor and cognitive brain circuits of brain-machine interactions

Silvia Marchesotti

Brain-machine interfaces (BMIs) allow the user to control an external device such as a robotic arm, a cursor, or an avatar in a virtual world through the real-time decoding of brain signals and without the involvement of the musculoskeletal system. Althoug ...

EPFL2016

Impact of HSD11B1 polymorphisms on BMI and components of the metabolic syndrome in patients receiving psychotropic treatments

Pierre Magistretti, Murielle Bochud

Background Metabolic syndrome (MetS) associated with psychiatric disorders and psychotropic treatments represents a major health issue. 11 beta-Hydroxysteroid dehydrogenase type 1 (11 beta-HSD1) is an enzyme that catalyzes tissue regeneration of active cor ...

Lippincott Williams & Wilkins2015

Influence of MCHR2 and MCHR2-AS1 Genetic Polymorphisms on Body Mass Index in Psychiatric Patients and In Population-Based Subjects with Present or Past Atypical Depression

Pierre Magistretti

Obesity development during psychotropic treatments represents a major health issue in psychiatry. Melanin-concentrating hormone receptor 2 (MCHR2) is a central receptor involved in energy homeostasis. MCHR2 shares its promoter region with MCHR2-AS1, a long ...

Public Library of Science2015

The role of leptin, melanocortin, and neurotrophin system genes on body weight in anorexia nervosa and bulimia nervosa

Pierre Magistretti

Objective: Although low weight is a key factor contributing to the high mortality in anorexia nervosa (AN), it is unclear how AN patients sustain low weight compared with bulimia nervosa (BN) patients with similar psychopathology. Studies of genes involved ...

Elsevier2014

A comparison of body mass index spatial dependence among adults and children in a Swiss general population

Stéphane Joost, Idris Guessous

Background: Body mass index (BMI) may cluster in space among adults and be spatially dependent. Whether BMI clusters among children and how adults and children BMI clusters are related remains unknown. We aimed to identify and to compare BMI spatial depend ...

Nature Publishing Group2014

Effects of Age, Sex and Treatment on Weight Loss Dynamics in Overweight People

David Atienza Alonso

The objective of this work is the evaluation of how sex, age and the kind of followed treatment affect weight loss, as well as the development of an explanation to assess the evolution of weight loss dynamics in overweight men and women. The methods use in ...

Canadian Science Publishing, Nrc Research Press2013

Influence of CRTC1 Polymorphisms on Body Mass Index and Fat Mass in Psychiatric Patients and the General Adult Population

Pierre Magistretti, Murielle Bochud

IMPORTANCE There is a high prevalence of obesity in psychiatric patients, possibly leading to metabolic complications and reducing life expectancy. The CREB-regulated transcription coactivator 1 (CRTC1) gene is involved in energy balance and obesity in ani ...

Amer Medical Assoc2013

Development and application of experimental tools to elucidate the gene regulatory network underlying adipogenesis

Carine Delattre-Gubelmann

Excess fat mass in obese individuals, which is characterized by an increase of white adipocyte cell size and number, significantly raises the risk of developing metabolic syndrome symptoms as well as cancer. A detailed understanding of the transcriptional ...

EPFL2013