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Publications associées (27)

The autism susceptibility kinase, TAOK2, phosphorylates eEF2 and modulates translation

Nagammal Neelagandan

Genes implicated in translation control have been associated with autism spectrum disorders (ASDs). However, some important genetic causes of autism, including the 16p11.2 microdeletion, bear no obvious connection to translation. Here, we use proteomics, g ...

Amer Assoc Advancement Science2024

Dense Image-based Predictions for Comics Analysis

Deblina Bhattacharjee

Dense image-based prediction methods have advanced tremendously in recent years. Their remarkable development has been possible due to the ample availability of real-world imagery. While these methods work well on photographs, their abilities do not genera ...

EPFL2023

Opportunities, Challenges, and Pitfalls in Making, Characterizing, and Understanding Polymer Brushes

Harm-Anton Klok

Polymer brushes have been theoretically described, their behavior under diverse conditions has been modeled, and their preparation via surface-initiated polymerizations (SIPs) has been progressively refined. However, despite three decades of research endea ...

American Chemical Society2023

Transformer Models for Vision

Jean-Baptiste Francis Marie Juliette Cordonnier

The recent developments of deep learning cover a wide variety of tasks such as image classification, text translation, playing go, and folding proteins. All these successful methods depend on a gradient-based learning algorithm to train a model on massive ...

EPFL2023

Type-Preserving Compilation of Class-Based Languages

Guillaume André Fradji Martres

The Dependent Object Type (DOT) calculus was designed to put Scala on a sound basis, but while DOT relies on structural subtyping, Scala is a fundamentally class-based language. This impedance mismatch means that a proof of DOT soundness by itself is ...

EPFL2023

The splay-list: a distribution-adaptive concurrent skip-list

Dan Alistarh, Amirkeivan Mohtashami

The design and implementation of efficient concurrent data structures has seen significant attention. However, most of this work has focused on concurrent data structures providing good worst-case guarantees, although, in real workloads, objects are often ...

SPRINGER2023

Unobtrusively Regulating Children’s Posture via Slow Visual Stimuli on Tablets

Pierre Dillenbourg, Barbara Bruno, Daniel Carnieto Tozadore, Chenyang Wang

Children’s retention of a proper body posture while interacting with educational tablet applications is important for both their physical health and task performance. In this work, we propose a new approach to unobtrusively induce postural changes in child ...

Association for Computing Machinery2023

Biochemistry of Aminoacyl tRNA Synthetase and tRNAs and Their Engineering for Cell-Free and Synthetic Cell Applications

Sebastian Maerkl, Ragunathan Bava Ganesh

Cell-free biology is increasingly utilized for engineering biological systems, incorporating novel functionality, and circumventing many of the complications associated with cells. The central dogma describes the information flow in biology consisting of t ...

FRONTIERS MEDIA SA2022

A Rapid Translational Immune Response Program in CD8 Memory T Lymphocytes

Linlin Cao

The activation of memory T cells is a very rapid and concerted cellular response that requires coordination between cellular processes in different compartments and on different time scales. In this study, we use ribosome profiling and deep RNA sequencing ...

American Association of Immunologists ; Oxford University Press2022

V-ATPase/TORC1-mediated ATFS-1 translation directs mitochondrial UPR activation in C. elegans

Johan Auwerx, Kristina Schoonjans, Felix Naef, Xiaoxu Li, Yang Li, Hao Li, Jia Liu, Yan Liu, Wen Gao, Amélia Lalou, Nagammal Neelagandan

To adapt mitochondrial function to the ever-changing intra- and extracellular environment, multiple mitochondrial stress response (MSR) pathways, including the mitochondrial unfolded protein response (UPRmt), have evolved. However, how the mitochondrial st ...

Rockefeller University Press2022

BMAT: An open-source BIDS managing and analysis tool

Meritxell Bach Cuadra, Francesco La Rosa

Magnetic Resonance Imaging (MRI) is an established technique to study in vivo neurological disorders such as Multiple Sclerosis (MS). To avoid errors on MRI data organization and automated processing, a standard called Brain Imaging Data Structure (BIDS) h ...

ELSEVIER SCI LTD2022

Overcoming decision paralysis—A digital twin for decision making in energy system design

François Maréchal, Julia Granacher, Tuong-Van Nguyen

The design of efficient energy systems, through the development of new technologies and the improvement of current ones, requires the use of rigorous process synthesis methods for generating and analysing design alternatives. We introduce a digital twin of ...

2022

Dipole polarizability of time-varying particles

Romain Christophe Rémy Fleury, Theodoros Koutserimpas, Mohammad Sajjad Mirmoosa

Invariance under time translation (or stationarity) is probably one of the most important assumptions made when investigating electromagnetic phenomena. Breaking this assumption is expected to open up novel possibilities and result in exceeding conventiona ...

2022

Improved framework to estimate travel time and derived distributions in hydrological control volumes

Mitra Asadollahi

Crossing properties of soil saturation, defined as the duration and excursion of soil saturation below and above certain thresholds, are key variables to ecosystem functioning and evolution by primarily influencing the plant and soil microbes physiological ...

EPFL2022

Rectilinear translation four-bar flexure mechanism based on four Remote Center Compliance pivots

Simon Nessim Henein, Charles Baur, Hubert Pierre-Marie Benoît Schneegans, Loïc Benoît Tissot-Daguette, Quentin Gubler

This paper presents a novel planar four-bar linkage compliant mechanism (called 4-RCC) based on four flexure-based Remote Center of Compliance (RCC) pivots. With particular configurations and dimensions, the beam shortening of the RCC pivots can compensate ...

euspen2022

Translating questions to estimands in randomized clinical trials with intercurrent events

Mats Julius Stensrud

Intercurrent (post-treatment) events occur frequently in randomized trials, and investigators often express interest in treatment effects that suitably take account of these events. Contrasts that naively condition on intercurrent events do not have a stra ...

2022

Cultural Adaptation, Validation, and Psychometric Description of the Pictorial Empathy Test (PET) in the Spanish Population

Maria del Carmen Sandi Perez

Research in psychology and social neuroscience distinguishes between dispositional and situational empathy for the cognitive and affective aspects of empathy. Yet, the Pictorial Empathy Test (PET) is one of the few brief tests focusing on situational affec ...

HOGREFE PUBLISHING CORP2022

On the ‘cultural transfer’ of modern architecture northwards - Akzeptiere: Das Buch und seine Geschichte

Chiara Monterumisi

"Akzeptiere: Das Buch und seine Geschichte" is the latest in-depth contribution by Atli Magnus Seelow, one of several by him on the 1930 Stockholm exhibition and the book accepetera, the 200-page text often referred to as ‘the manifesto of Swedish function ...

2021

Content-Preserving Unpaired Translation from Simulated to Realistic Ultrasound Images

Devavrat Tomar

Interactive simulation of ultrasound imaging greatly facilitates sonography training. Although ray-tracing based methods have shown promising results, obtaining realistic images requires substantial modeling effort and manual parameter tuning. In addition, ...

Springer2021

System for planning and/or providing neuromodulation

Grégoire Courtine, Marco Capogrosso, Fabien Bertrand Paul Wagner, Vincent Delattre, Karen Minassian

The present invention relates to systems and methods for planning and/or providing neuromodulation One example system includesa stimulation related basic data storage module for storing stimulation related basic data,a stimulation related response data sto ...

2021