Roger G. ClercEnseignement et PhD Cours The making of an innovative medicine BIO-698
Christian HeinisEnseignement et PhD Doctorant·es actuel·les Thomas Julien Denis Emel, Alessandro Scapozza, Nathan Moïse De Sadeleer, Florian Handel, Hugo André Clerc, Frédéric Brantschen, Grégoire Menoud, Ines Michrafy, Jonathan Schmitt, Laura Elena Massaad A dirigé les thèses EPFL de Jeremy Touati, Shiyu Chen, Sophie Venet-Bonnot, Lisa Pollaro, Inmaculada Rentero Rebollo, Philippe Diderich, Charlotte Urech-Varenne, Silvia Bellotto, Davide Bertoldo, Alessandro Zorzi, Camille Villequey, Jonas Alfred Karl Wilbs, Grigory Ka
Bruno Emanuel Ferreira De Sousa CorreiaThroughout my PhD and postdoctoral studies I was trained in world-renowned laboratories and institutions in the United States of America (University of Washington and The Scripps Research Institute). Very early in my scientific career I found out my fascination about protein structure and function. My PhD studies evolved in the direction of immunogen design and vaccine engineering which sparked my interest in the many needs and opportunities in vaccinology and translational research. My efforts resulted in an enlightening piece of work where for the first time, computationally designed immunogens elicited potent neutralizing antibodies. During my postdoctoral studies I joined a chemical biology laboratory at the Scripps Research Institute. In this stage I developed novel chemoproteomics methods for the identification of protein-small molecule interaction sites in complex proteomes. In March 2015, I joined the École Polytechnique Fédérale de Lausanne (EPFL) – Switzerland as a tenure track assistant professor. The focus of my research group is to develop computational tools for protein design with particular emphasis in applying these strategies to immunoengineering (e.g. vaccine and cancer immunotherapy). The activities in my laboratory focus on computational design methods development and experimental characterization of the designed proteins. Our laboratory has been awarded with 2 prestigious research grants from the European Research Council. Lastly, I have been awarded the prize for best teacher of Life sciences in 2019.
Suliana ManleyExpertise
Super-resolution fluorescence microscopy, single molecule imaging in cells, cellular biophysics, bacterial cell cycle
Enseignement et PhD Doctorant·es actuel·les Emine Berna Durmus, Santiago Nicolás Rodriguez Alvarez, Laila Elfeky, Alara Kiris, Hale-Seda Ivo Radoykova A dirigé les thèses EPFL de Julia Gunzenhäuser, Aleksandr Benke, Lina Carlini, Andrea Callegari, Aster Louis K Vanhecke, Anna Archetti, Dora Mahecic, Timo Henry René Rey, Julius Winter, Chen Zhang, Jenny Sülzle, Sheda Ben Nejma Cou
Xile HuXile Hu was born in 1978 in Putian, southeastern China. He entered the Peking University in Beijing in 1996. Besides learning too little chemistry, his biggest regret in the college was not able to correct his southern accent in Mandarin. After graduated from PKU, he went to the United States and began his doctoral studies at the University of California, San Diego. In December 2004, he finished with a Ph.D. in chemistry and some fond memories of the beautiful city of San Diego. He then moved to the Los Angeles area and become a postdoctoral scholar at the California Institute of Technology. There he enjoyed numerous stimulating scientific (and other) discussions with friends and colleagues. He also made plenty of friends outside the campus and was a frequent in many local Chinese restaurants. In 2007, after two pleasant visits to Switzerland, he decided to move across the continent one more time and join the faculty of the École Polytechnique Fédérale de Lausanne (EPFL). He now directs the Laboratory of Inorganic Synthesis and Catalysis and is interested in developing chemistry for synthesis, energy and sustainability.
Florence PojerExpertise
MER and Head of Unit - Protein Production and Structure Reseach Core Facility within the Life Sciences School - PTPSP: Expertise in Integrative protein Structural Biology (mainly X-ray Crystallography and Cryo-EM) and production of macromolecules in mammalian and bacterial cells. Innovate4Life team member at SV: i4L supports the next generation of entrepreneurs through education, mentorship, and funding, to translate life sciences discoveries into technologies that benefit society.Education and
Stewart ColeProfessor Stewart Cole is an international authority in bacterial molecular-genetics and genomics. He has made outstanding contributions in several fields including: bacterial anaerobic electron transport; genome analysis of retroviruses and papillomaviruses; antibiotic resistance mechanisms; and the molecular microbiology of toxigenic clostridia. His studies on isoniazid and multidrug resistance in Mycobacterium tuberculosis, together with his pioneering work on the pathogenicity, evolution and genomics of the tubercle and leprosy bacilli, have made him an undisputed leader in the field of mycobacterial research. The findings of his research are of direct relevance to public health and disease-control in both the developing world and the industrialised nations. He has published over 250 scientific papers and review articles, and holds many patents.
Paul Joseph DysonPaul Dyson rejoignit l’EPFL en 2002 à la tête du Laboratoire de chimie organométallique et médicinale de l’Institut des sciences et ingénierie chimiques, dont il en assuma ensuite la direction entre 2008 et 2016.
Le prof. Dyson a été récompensé par de nombreux prix dont le Prix Werner de la Société Suisse de Chimie en 2004, le Prix pour les réalisations exceptionnelles en chimie bio organométallique en 2010, la Médaille du Centenaire de la naissance de Luigi Sacconi (2011) de la Société Italienne de Chimie, le Prix de Chimie bio-inorganique de la Royal Society of Chemistry en 2015, le Prix européen pour une chimie durable de la Société Européenne de Chimie en 2018 et le Prix pour la chimie verte de la Royal Society of Chemistry en 2020.
Le prof. Dyson est également mentionné dans la liste établie par Clarivate des chercheurs les plus cités (Clarivate Highly Cited Researcher), avec un H-index >110 (Web of Science et Google Scholar). Paul Dyson a été élu membre de la Royal Société de Chimie en 2010, membre de l’Académie Européenne des Sciences en 2019 et membre à vie de l’Association Américaine pour l’Avancement de la Science en 2020. Au cours des dernières années il s’est vu décerner le titre de Professeurs Hôte par l’Université de Bourgogne, l’Université de Pierre et Marie Curie, l’Université de Vienne, l’Université de Rome Tor Vergara, l'Ecole Nationale Supérieure de chimie de Paris (Chimie ParisTech) et par l’Université de Shangai Jiao Tong.
De 2016 à 2021 il était membre du conseil de la recherche de la division de mathématique, sciences naturelles et de l’ingénieur du Fonds National Suisse. En 2021, il a été nommé doyen de la Faculté des Sciences de Base.
Vassily HatzimanikatisEnseignement et PhD Doctorant·es actuel·les Denis Alain Henri Lucien Joly, Luca Milazzo, David Liaskos, Konrad Lagoda, Omar Keshk, Yigit Sibal, Ioannis Tzegiannakis A dirigé les thèses EPFL de Keng Cher Soh, Julien Racle, Noushin Hadadi, Stefano Andreozzi, Stepan Tymoshenko, Meriç Ataman, Joana Raquel Pinto Vieira, Tiziano Dallavilla, Yves Berset, Anush Chiappino-Pepe, Milenko Tokic, Tuure Eelis Hameri, Jasmin Maria Hafner, Homa Mohammadi Peyhani, Daniel Robert Weilandt, Zhaleh Hosseini, Sofia Tsouka, Mar
Marc ChambonEnseignement et PhD Cours Methods: from disease models to therapy BIOENG-518 Ce cours décrira les méthodes qui sont à la base des approches translationnelles depuis la génération et la caractérisation des modèles des maladies jusqu'aux applications thérapeutiques. Les bases théoriques seront complétées par des rotations pratiques dans les plateformes technologiques.
David HackerEnseignement et PhD A co-dirigé les thèses EPFL de Agata Oberbek, Yashas Rajendra, Xiao Shen, Dominique Terry Monteil Jr, Sowmya Balasubramanian Cours Recombinant protein expression in animal cells for applications in medicine and structural biology BIO-701
