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Concept

Raloxifène

Publications associées (4)

Anticytolytic Screen Identifies Inhibitors of Mycobacterial Virulence Protein Secretion

Stewart Cole, Claudia Sala, Andrej Benjak, Anthony Vocat, Ruben Hartkoorn, Ming Zhang, Jan Lars Rybniker, Edina Rita Székely

Mycobacterium tuberculosis (Mtb) requires protein secretion systems like ESX-1 for intracellular survival and virulence. The major virulence determinant and ESX-1 substrate, EsxA, arrests phagosome maturation and lyses cell membranes, resulting in tissue d ...

Cell Press2014

The bile acid membrane receptor TGR5: a valuable metabolic target

Johan Auwerx, Kristina Schoonjans, Thijs Pols, Lilia Noriega Lopez, Mitsunori Nomura

Bile acids (BAs) are amphipathic molecules that facilitate the uptake of lipids, and their levels fluctuate in the intestines as well as in the circulation depending on food intake. Besides their role in dietary lipid absorption, BAs function as signaling ...

2011

The bile acid membrane receptor TGR5 as an emerging target in metabolism and inflammation

Johan Auwerx, Kristina Schoonjans, Thijs Pols, Lilia Noriega Lopez, Mitsunori Nomura

Bile acids (BAs) are amphipathic molecules that facilitate the uptake of lipids, and their levels fluctuate in the intestine as well as in the blood circulation depending on food intake. Besides their role in dietary lipid absorption, bile acids function a ...

Elsevier2011

Photodynamic endometrial ablation: Morphological study

Georges Wagnières

Background and Objectives Endometriumablation provides an alternative treatment modality to hysterectomy for dysfunctional uterine bleeding (DUB). Its feasibility was demonstrated in animal studies. The purpose of this study was the evaluation of histol ...

Wiley-Blackwell2003