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Concept

Nucleic acid notation

Publications associées (25)

Innate immunity against retroviral pathogens: from an ambiguous genetic self to novel therapeutic approaches

Didier Trono

Almost half of the human genome is derived from exogenous genetic invaders, most of them related to retroviruses. This is the consequence of longstanding interactions between retroelements and higher organisms, governed by a delicate equilibrium between vi ...

Swiss Medical Publishers Ltd / EMH Swiss Medical Publishers2009

Probabilistic base calling of Solexa sequencing data

Felix Naef, Jacques Rougemont, Christian Iseli, Arnaud Amzallag

BACKGROUND: Solexa/Illumina short-read ultra-high throughput DNA sequencing technology produces millions of short tags (up to 36 bases) by parallel sequencing-by-synthesis of DNA colonies. The processing and statistical analysis of such high-throughput dat ...

BioMed Central2008

Method of Nucleotide Detection

Gerardo Turcatti

The invention relates to an additive which can be added to buffers used in nucleotide detection processes and improved methods of nucleic acid sequencing using this additive. In particular the invention relates to use of the additive to improve the efficie ...

2008

Triblock copolymers for cytoplasmic delivery of gene-based drugs

Jeffrey Alan Hubbell

The invention features a triblock copolymer including a hydrophilic block a hydrophobic block and a positively charged block capable of reversibly complexing a negatively charged molecule, e.g., a nucleic acid, wherein the hydrophobic block is disposed bet ...

2007

Improved method of nucleotide detection

Gerardo Turcatti

2007