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Concept

Conduit auditif externe humain

Publications associées (16)

Design and modelling of a compliant constant-force surgical tool for objective assessment of ossicular chain mobility

Simon Nessim Henein, Charles Baur, Loïc Benoît Tissot-Daguette

Surgeons generally assess the mobility of the ossicle chain by manual palpation using rigid elongated hooks inserted through the ear canal. As the applied forces are in the range of a few grams equivalent force, the measurement remains subjective and its r ...

IEEE2021

Inner ear cellular imaging through scattering bone

Demetri Psaltis, Marilisa Romito

Inner ear imaging is important for the assessment of hearing disorders. A major cause of hearing loss is the damage to the sensory hair cells, which are located inside the cochlea, a spiral-shaped bone in the inner ear. Imaging of intracochear hair cells i ...

SPIE-INT SOC OPTICAL ENGINEERING2019

Bulged Eardrum Detection From 3D Data

Pascal Frossard, Ivana Tosic, Sofia Karygianni

Bulging is a medical characteristic of the eardrum that is crucial for the diagnosis of acute otitis media. This work proposes a novel classification method for distinguishing bulged eardrums from non-bulged ones. The method uses novel key features extract ...

IEEE2018

Characterization of a B16-F10 melanoma model locally implanted into the ear pinnae of C57BL/6 mice

Esra Güç

The common experimental use of B16-F10 melanoma cells focuses on exploring their metastatic potential following intravenous injection into mice. In this study, B16-F10 cells are used to develop a primary tumor model by implanting them directly into the ear ...

2018

Surgical Anatomy of the Human Round Window Region: Implication for Cochlear Endoscopy Through the External Auditory Canal

Demetri Psaltis, Simon Nessim Henein

Objective: To enable development of an endoscope for cellular-level optical imaging of the inner ear. Study Design: A prospective study of 50 cadaveric human temporal bones to define detailed surgical anatomy of the round window (RW) region and the range o ...

Lippincott, Williams & Wilkins2016

Objective and subjective validation of an active control approach to reduce the occlusion effect in hearing aids

Hervé Lissek, Thomas Stefan Zurbrügg

The occlusion effect refers to the altered perception of one's own voice when the ear canal is fully or partially obstructed. Conventional countermeasures include the use of large vent bores or open fittings on the one hand and fittings reaching as deep as ...

S Hirzel Verlag2015

Abrogation of HMX1 Function Causes Rare Oculoauricular Syndrome Associated With Congenital Cataract, Anterior Segment Dysgenesis, and Retinal Dystrophy

PURPOSE. To define the phenotypic manifestation, confirm the genetic basis, and delineate the pathogenic mechanisms underlying an oculoauricular syndrome (OAS). METHODS. Two individuals from a consanguineous family underwent comprehensive clinical phenotyp ...

Assoc Research Vision Ophthalmology Inc2015

Investigations on the physical factors influencing the ear canal occlusion effect caused by hearing aids

Hervé Lissek, Thomas Stefan Zurbrügg

The occlusion effect refers to the altered perception of one's own voice when the ear canal is fully or partially obstructed. While the loudness increase due to body conducted sounds requires an assessment by psychoacoustic methods, the ratio of sound pres ...

Hirzel Verlag2014

Active Control mitigating the Ear Canal Occlusion Effect caused by Hearing Aids

Thomas Stefan Zurbrügg

The World Health Organization (WHO) estimates the prevalence of a disabling hearing loss to be above 5% world-wide 1. A treatment with a hearing aid - be it behind-the-ear (BTE), in-the-ear (ITE) or receiver-in-canal (RIC) - involves some degree of occlusi ...

EPFL2014

Normal Dendritic Cell Mobilization to Lymph Nodes under Conditions of Severe Lymphatic Hypoplasia

Melody Swartz

To address the requirement for lymphatic capillaries in dendritic cell (DC) mobilization from skin to lymph nodes (LNs), we used mice bearing one inactivated allele of vascular endothelial growth factor receptor 3 (VEGFR3) where skin lymphatic capillaries ...

American Association of Immunologists ; Oxford University Press2013

Two-photon microscopy of the mouse cochlea in situ for cellular diagnosis

Demetri Psaltis, Ye Pu, Chia-Lung Hsieh, Ye Pu, Xin Yang

Sensorineural hearing loss is the most common type of hearing loss worldwide, yet the underlying cause is typically unknown because the inner ear cannot be biopsied today without destroying hearing, and intracochlear cells have not been imaged with resolut ...

SPIE Society of Photo-optical Instrumentation Engineers2013

Design of a Semi-Implantable Hearing Device for Direct Acoustic Cochlear Stimulation

Yves Perriard, Hans Bernhard

A new hearing therapy based on direct acoustic cochlear stimulation was developed for the treatment of severe to profound mixed hearing loss. The device efficacy was validated in an initial clinical trial with four patients. This semi-implantable investiga ...

Institute of Electrical and Electronics Engineers2011

Potential novel drug carriers for inner ear treatment: hyperbranched polylysine and lipid nanocapsules

Harm-Anton Klok, Markus Scholl, Zuzana Kadlecova

Aim: Treatment of sensorineural hearing loss could be advanced using novel drug carriers such as hyperbranched polylysine (HBPL) or lipid nanocapsules (LNCs). This study examined HBPL and LNCs for their cellular uptake and possible toxicity in vitro and in ...

Future Medicine2009

Open innovation in SMEs: Trends, motives and management challenges

Vareska van de Vrande

Open innovation has so far been studied mainly in high-tech, Multinational enterprises. This exploratory paper investigates if open innovation practices are also applied by small- and medium-sized enterprises (SMEs). Drawing oil I database collected from 6 ...

Elsevier2009

Mutation in the human homeobox gene NKX5-3 causes an oculo-auricular syndrome

Several dysmorphic syndromes affect the development of both the eye and the ear, but only a few are restricted to the eye and the external ear. We describe a developmental defect affecting the eye and the external ear in three members of a consanguineous f ...

2008

A physical interpretation of the equal area rule

Farhad Rachidi-Haeri, Marcos Rubinstein, Abraham Rubinstein

This paper presents a derivation and a physical interpretation of the equal area rule (EAR) for wire-grid simulation of surfaces. We propose a new procedure that leads to a formulation for obtaining the radii for an arbitrarily meshed surface. A simple com ...

2006