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Concept

Acide lactique

Publications associées (31)

A Sustainable Approach to Produce Stiff, Super-Tough, and Heat-Resistant Poly(lactic acid)-Based Green Materials

Nicolas Candau, Oguzhan Oguz

Circumventing inherent embrittlement, poor heat resistance, and melt elasticity of poly(lactic acid) (PLA) without compromising its remarkable stiffness and strength has become a particular challenge in polymer science due to increasing demand for green ma ...

AMER CHEMICAL SOC2019

A biosensor for measuring NAD(+) levels at the point of care

Johan Auwerx, Kai Johnsson, Luc Patiny, Elena Katsyuba, Lin Xue, Qiuliyang Yu

The cellular level of nicotinamide adenine dinucleotide (NAD(+)), through its different functions, affects cellular metabolism and signalling(1-3). A decrease in the NAD(+) content has been associated with various pathologies and physiological aging(4,5), ...

NATURE PUBLISHING GROUP2019

Recycled Glass Fiber Composites from Wind Turbine Waste for 3D Printing Feedstock: Effects of Fiber Content and Interface on Mechanical Performance

Rodolphe Henri

This research validates the viability of a recycling and reusing process for end-of-life glass fiber reinforced wind turbine blades. Short glass fibers from scrap turbine blades are reclaimed and mixed with polylactic acid (PLA) through a double extrusion ...

2019

Consolidated bioprocessing of lignocellulosic biomass to lactic acid by a synthetic fungal-bacterial consortium

Jeremy Luterbacher

Consolidated bioprocessing (CBP) of lignocellulosic feedstocks to platform chemicals requires complex metabolic processes, which are commonly executed by single genetically engineered microorganisms. Alternatively, synthetic consortia can be employed to co ...

2018

Hyperpolarized C-13 Magnetic Resonance Spectroscopy Reveals the Rate-Limiting Role of the Blood-Brain Barrier in the Cerebral Uptake and Metabolism of L-Lactate in Vivo

Arnaud Comment, Bernard Lanz, Josefina Adriana Maria Bastiaansen, Tian Cheng, Mor-Miri Mishkovsky, Hikari Ananda Infinity Yoshihara, Yuhei Takado, Sylvain Eric Lengacher

The dynamics of L-lactate transport across the blood-brain barrier (BBB) and its cerebral metabolism are still subject to debate. We studied lactate uptake and intracellular metabolism in the mouse brain using hyperpolarized C-13 magnetic resonance spectro ...

2018

Nickel pincer model of the active site of lactate racemase involves ligand participation in hydride transfer

Rosario Scopelliti, Xile Hu, Anne-Clémence Corminboeuf, Matthew Wodrich, Tao Xu

Pincer complexes are widely applied in homogeneous catalysis. However, only very recently has the first pincer complex been discovered in the active site of a metalloenzyme, namely, lactate racemase. Here, we report a synthetic model of the active site of ...

Natl Acad Sciences2017

Remarkable enhancement of bacterial inactivation in wastewater through promotion of solar photo-Fenton at near-neutral pH by natural organic acids

César Pulgarin, Stefanos Giannakis

In this work, the near-neutral photo-Fenton process, as a means of wastewater disinfection, was enhanced by the addition of Organic Acids (OAs), namely citric, ascorbic, tartaric and caffeic acid. The addition of OAs exhibited significant bacterial inactiv ...

Elsevier2017

Assessment of brain metabolite correlates of AAV-mediated overexpression of human alpha-synuclein in cortical neurons by in vivo(1) H-MR spectroscopy at 9.4 T

Sarah Catherine Sonnay

In this study, we used proton-localized spectroscopy ((1) H-MRS) for the acquisition of the neurochemical profile longitudinally in a novel rat model of human wild type alpha-synuclein (a-syn) overexpression. Our goal was to find out if the increased a-syn ...

Wiley-Blackwell2016

Environmental impact assessment of lignocellulosic lactic acid production: Integrated with existing sugar mills

Pavel Vaskan

Lactic acid (LA) is considered for the diversification and value addition to sugar industry in South Africa, through a bioconversion of sugarcane bagasse and leaves. A bioconversion process was modeled in Aspen Plus (R) V8.6 and its environmental impacts w ...

Institution of Chemical Engineers2016

Compartmentalised energy metabolism supporting glutamatergic neurotransmission in response to increased activity in the rat cerebral cortex: A 13C MRS study in vivo at 14.1 T

Rolf Gruetter, João Miguel das Neves Duarte, Nathalie Just, Sarah Catherine Sonnay

Many tissues exhibit metabolic compartmentation. In the brain, while there is no doubt on the importance of functional compartmentation between neurons and glial cells, there is still debate on the specific regulation of pathways of energy metabolism at di ...

Nature Publishing Group2016

L-Lactate protects neurons against excitotoxicity: implication of an ATP-mediated signaling cascade

Pierre Magistretti, Pierre Marquet, Igor Allaman, Pascal Jourdain

Converging experimental data indicate a neuroprotective action of L-Lactate. Using Digital Holographic Microscopy, we observe that transient application of glutamate (100 μM; 2 min) elicits a NMDA-dependent death in 65% of mouse cortical neurons in culture ...

Nature Research2016