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Publications associées (30)

Ukrainian Literary Imaginaries of Past after 1991: From Substitution to Restoration?

This chapter offers a new view of post-Soviet Ukrainain literary memory as expressed in varous texts, redefining the role of clashing narratives of the past under the divisive political and social conditions of upheavals, crises, and military conflicts. Th ...

Routledge2024

Face your fears: attenuating remote fear memories by reconsolidation-updating

Johannes Gräff, Bianca Ambrogina Silva

Traumatic events generate some of the most enduring memories, yet little is known about how long-lasting fear memories can be attenuated. In this review, we collect the surprisingly sparse evidence on remote fear memory attenuation from both animal and hum ...

ELSEVIER SCIENCE LONDON2023

Tissue clearing applications in memory engram research

Johannes Gräff

A memory engram is thought to be the physical substrate of the memory trace within the brain, which is generally depicted as a neuronal ensemble activated by learning to fire together during encoding and retrieval. It has been postulated that engram cell e ...

FRONTIERS MEDIA SA2023

A dynamic attractor network model of memory formation, reinforcement and forgetting

Wulfram Gerstner, Chiara Gastaldi

Empirical evidence shows that memories that are frequently revisited are easy to recall, and that familiar items involve larger hippocampal representations than less familiar ones. In line with these observations, here we develop a modelling approach to pr ...

Public Library Science2023

Brain-wide screen of prelimbic cortex inputs reveals a functional shift during early fear memory consolidation

Johannes Gräff, Lucie Pauline Dixsaut

Memory formation and storage rely on multiple interconnected brain areas, the contribution of which varies during memory consolidation. The medial prefrontal cortex, in particular the prelimbic cortex (PL), was traditionally found to be involved in remote ...

2022

Where does the engram come from? Study of prefrontal cortex inputs during memory consolidation

Lucie Pauline Dixsaut

The formation and storage of memories has been under deep investigation for several decades. Nevertheless, the precise contribution of each brain region involved in this process and the interplay between them across memory consolidation is still largely de ...

EPFL2022

Epigenetic memory aids: Synaptic and molecular effects of HDAC inhibition that support memory formation

Allison Marie Burns

Learning and memory rely on synaptic communication in which intracellular signals are transported to the nucleus to stimulate transcriptional activation. Memory induced transcriptional increases are accompanied by alterations to the epigenetic landscape an ...

EPFL2022

The HDAC inhibitor CI-994 acts as a molecular memory aid by facilitating synaptic and intracellular communication after learning

Johannes Gräff, Jose Vicente Sanchez Mut, Giulia Santoni, Allison Marie Burns

Long-term memory formation relies on synaptic plasticity, neuronal activity-dependent gene transcription, and epigenetic modifications. Multiple studies have shown that HDAC inhibitor (HDACi) treatments can enhance individual aspects of these processes and ...

2022

Epigenetic plasticity as a signature for memory allocation

Giulia Santoni

Long-lasting memories are stored in a small set of neurons scattered throughout the brain, so-called engram cells. To define a stable engram each region of the brain involved in memory storage recruits between 5 and 20 percent of excitatory neurons. In par ...

EPFL2022

Mechanical reinforcement and memory effect of strain-induced soft segment crystals in thermoplastic polyurethane-urea elastomers

Nicolas Candau, Oguzhan Oguz, Adrien Julien Demongeot

An amorphous poly(urethane-urea) copolymer composed of 70 wt% poly(ethylene oxide) (PEO) soft segments (SS) (Mw = 2000 g mol−1) and 30 wt% cycloaliphatic hard segments (HS) was subjected to in-situ X-Rays during tensile deformation. Mechanical hardening at ...

2021

Re-creating Memories of Gulou: Three Temporalities and Emotions

Florence Graezer Bideau

In 2012, a project proposed by local authorities aimed to revitalise, after a century of interruption, the use of Beijing’s Bell and Drum Towers and the social traditions associated with them. As a result, more than 100 households living in 66 traditional ...

Routledge2021

Postmortem memory of public figures in news and social media

Robert West

Deceased public figures are often said to live on in collective memory. We quantify this phenomenon by tracking mentions of 2,362 public figures in English-language online news and social media (Twitter) 1 y before and after death. We measure the sharp spi ...

National Academy of Sciences2021

Engram cell connectivity: an evolving substrate for information storage

Maurizio Ferdinando Pezzoli

Understanding memory requires an explanation for how information can be stored in the brain in a stable state. The change in the brain that accounts for a given memory is referred to as an engram. In recent years, the term engram has been operationalized a ...

CURRENT BIOLOGY LTD2021

Early life adoption shows rearing environment supersedes transgenerational effects of paternal stress on aggressive temperament in the offspring

Maria del Carmen Sandi Perez, Olivia Zanoletti, Guillaume Poirier

Prenatal experience and transgenerational influences are increasingly recognized as critical for defining the socio-emotional system, through the development of social competences and of their underlying neural circuitries. Here, we used an established rat ...

2021

Video Prediction Recalling Long-term Motion Context via Memory Alignment Learning

Hakgu Kim

Our work addresses long-term motion context issues for predicting future frames. To predict the future precisely, it is required to capture which long-term motion context (e.g., walking or running) the input motion (e.g., leg movement) belongs to. The bott ...

IEEE COMPUTER SOC2021

Large-Scale Graph Processing on FPGAs with Caches for Thousands of Simultaneous Misses

Paolo Ienne, Mikhail Asiatici

Efficient large-scale graph processing is crucial to many disciplines. Yet, while graph algorithms naturally expose massive parallelism opportunities, their performance is limited by the memory system because of irregular memory accesses. State-of-the-art ...

IEEE COMPUTER SOC2021

A dynamical systems approach to synaptic consolidation and associations of concepts in hippocampus

Chiara Gastaldi

In the present work, we approach two key aspects of memory formation: associative memory and synaptic consolidation. The storage of associative memory is commonly related to the medial temporal lobe in humans. Experimental evidence shows that the memories ...

EPFL2021

La mémoire collective et l'espace. Traces, récits et expériences autour d'un paysage urbain romain

Lucia Bordone

This PhD thesis explores the way multiple and tenuous links connect collective memory and space in the contemporary city. It does so through a field enquiry carried out in Rome, Italy. This palimpsest-city has a particular relationship to the past, which c ...

EPFL2020

Social Representations of Mexico City Historic Center: Heritage and Controversial Memories

Lesslie Astrid Herrera Quiroz

In this paper, we present the results of a research project that deals with the controversial memories of historic urban landscapes that have been designated as World Heritage sites by UNESCO. We observe - through the study of social representations of Mex ...

JOHANNES KEPLER UNIV, INST PAEDAGOGIK & PSYCHOLOGIE2020

Write Termination circuits for RRAM : A Holistic Approach From Technology to Application Considerations

David Atienza Alonso, Alexandre Sébastien Julien Levisse, Marco Antonio Rios

While Resistive Random Access Memories (RRAM) are perceived nowadays as a promising solution for the future of computing, these technologies suffer from intrinsic variability regarding programming voltage, switching speed and achieved resistance values. Wr ...

IEEE2020