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Concept

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Publications associées (6)

Analysis of Polycerate Mutants Reveals the Evolutionary Co-option of HOXD1 for Horn Patterning in Bovidae

Denis Duboule

In the course of evolution, pecorans (i.e., higher ruminants) developed a remarkable diversity of osseous cranial appendages, collectively referred to as "headgear," which likely share the same origin and genetic basis. However, the nature and function of ...

OXFORD UNIV PRESS2021

Beyond silence : a functional and evolutionary study of KRAB zinc finger proteins

Pierre-Yves Joseph Laurent Helleboid

Transposable elements (TEs) are genetic units capable of spreading within the genomes of their host. TEs contribute a readily recognizable 45% of the human DNA, reflecting in part their co-option for some as source of protein-coding sequences, for others a ...

EPFL2019

How synthetic fingerprints can improve pre-selection of MCC pairs using local quality measures

Andrzej Drygajlo, Mohammad Hamed Izadi

A major source of errors in fingerprint recognition systems is poor quality of fingerprints. Local quality of fingerprints plays an important role in these systems to ensure high recognition performance. Recently an improved fingerprint matching method is ...

2015

The Drosophila MAPK p38c Regulates Oxidative Stress and Lipid Homeostasis in the Intestine

Bruno Lemaitre, Sveta Chakrabarti

The p38 mitogen-activated protein (MAP) kinase signaling cassette has been implicated in stress and immunity in evolutionarily diverse species. In response to a wide variety of physical, chemical and biological stresses p38 kinases phosphorylate various su ...

Public Library of Science2014

Sorting genomes with rearrangements and segmental duplications through trajectory graphs

Bernard Moret, Yu Lin, Mingfu Shao

We study the problem of sorting genomes under an evolutionary model that includes genomic rearrangements and segmental duplications. We propose an iterative algorithm to improve any initial evolutionary trajectory between two genomes in terms of parsimony. ...

Biomed Central Ltd2013

Tinkering with constraints in the evolution of the vertebrate limb anterior-posterior polarity

Denis Duboule

Genes belonging to both HoxA and HoxD clusters are required for proper vertebrate limb development. Mice lacking all, or parts of, Hoxa and Hoxd functions in forelimbs, as well as mice with a gain of function of these genes in the early limb bud, have help ...

2007