Concept

Lésion axonale diffuse

Publications associées (29)

Diffusion-weighted imaging evidence of altered white matter development from late childhood to early adulthood in Autism Spectrum Disorder

Djalel Eddine Meskaldji, Fikret Isik Karahanoglu

Autism Spectrum Disorder (ASD) is thought to reflect disrupted development of brain connectivity characterized by white matter abnormalities and dyscoordination of activity across brain regions that give rise to core features. But there is little consensus ...

2018

Central nervous system microbleeds in the acute phase are associated with structural integrity by DTI one year after mild traumatic brain injury: A longitudinal study

Jean-Philippe Thiran, Alessandro Daducci, David Paul Roger Romascano

Introduction: Several imaging modalities are under investigation to unravel the pathophysiological mystery of delayed performance deficits in patients after mild traumatic brain injury (mTBI). Although both imaging and neuropsychological studies have been ...

ELSEVIER URBAN & PARTNER SP Z O O2018

An ultra-fast mechanically active cell culture substrate

Herbert Shea, Samuel Rosset, Cristina Martin Olmos, Matthias Imboden, Alexandre Poulin, Francesca Sorba

We present a mechanically active cell culture substrate that produces complex strain patterns and generates extremely high strain rates. The transparent miniaturized cell stretcher is compatible with live cell microscopy and provides a very compact and por ...

Nature Research2018

Statistical Learning Impairments as a Consequence of Stroke

Albulena Jashari-Shaqiri

Statistical learning is the implicit learning of the contingencies between sequential stimuli, typically from mere exposure. It is present from infancy onward, and plays a role in functions from language learning to selective attention. Despite these obser ...

2018

A microfabricated nerve-on-a-chip platform for rapid assessment of neural conduction in explanted peripheral nerve fibers

Stéphanie Lacour, Diego Ghezzi, Sandra Gribi

Peripheral nerves are anisotropic and heterogeneous neural tissues. Their complex physiology restricts realistic in vitro models, and high resolution and selective probing of axonal activity. Here, we present a nerve-on-a-chip platform that enables rapid e ...

Nature Research2018

Efficient transdifferentiation of human dermal fibroblasts into skeletal muscle

Noaf Salah Ali Alwahab

Skeletal muscle holds significant regenerative potential but is incapable of restoring tissue loss caused by severe injury, congenital defects or tumour ablation. Consequently, skeletal muscle models are being developed to study human pathophysiology and r ...

WILEY2018

EEG paradigms as a supplemental tool to behavioral assessments of DOC

José del Rocio Millán Ruiz, Andrea Serino, Serafeim Perdikis

Introduction Diagnosis and prediction of recovery in the acute phase of disorders of consciousness (DOC) are critical for subsequent medical decisions. However, reliable assessment remains elusive due to the inability of current validated clinical scales t ...

2017

Cortico-reticulo-spinal circuits mediate functional recovery after spinal cord contusion

Léonie Asboth

After a spinal cord injury (SCI), only half of affected individuals regain voluntary control of leg movements below the level of the lesion. Anatomical, electrophysiological and imaging data revealed that even the most severe forms of SCI usually spare a s ...

EPFL2017

Biodegradable scaffolds promote tissue remodeling and functional improvement in non-human primates with acute spinal cord injury

Grégoire Courtine

Tissue loss significantly reduces the potential for functional recovery after spinal cord injury. We previously showed that implantation of porous scaffolds composed of a biodegradable and biocompatible block copolymer of Poly-lactic-co-glycolic acid and P ...

2017