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Concept

Art autistique

Publications associées (5)

A new rat model of creatine transporter deficiency reveals behavioral disorder and altered brain metabolism

Maria del Carmen Sandi Perez, Cristina Ramona Cudalbu Moldovan, Dunja Simicic, Jocelin Grosse, Hirotaka Yamada

Creatine is an organic compound used as fast phosphate energy buffer to recycle ATP, important in tissues with high energy demand such as muscle or brain. Creatine is taken from the diet or endogenously synthetized by the enzymes AGAT and GAMT, and specifi ...

Nature Research2021

Building a Question-Answering Chatbot using Forum Data in the Semantic Space

Pierre Dillenbourg, Marc Laperrouza, Khalil Mrini

We build a conversational agent which knowledge base is an online forum for parents of autistic children. We collect about 35,000 threads totalling some 600,000 replies, and label 1% of them for usefulness using Amazon Mechanical Turk. We train a Random Fo ...

2018

Hyper-emotional neurophysiology in a rat model of autism

Mônica Regina Favre

Autism is a pervasive neurodevelopmental disorder of unknown etiology, characterized by a spectrum of symptoms of social impairment, abnormal communication, and unusual restricted, inflexible behaviors. Patients also frequently present various levels of se ...

EPFL2013

Network Activity and Plasticity

Vincent Delattre

The cortex must maintain balanced levels of neural activity to correctly integrate inputs and to provide contextually meaningful outputs. Neuronal excitation is counterbalanced by various forms of inhibition such as spike frequency adaptation, short- and l ...

EPFL2013

Altered neocortical microcircuitry in the valproic acid rat model of autism

Tania Rinaldi

Autism is a wide-spectrum disorder with early childhood onset, affecting general cognitive capabilities and, in particular, complex information processing. Although interesting directions of research start to appear, the precise causes of the disorder and ...

EPFL2006