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Concept

Tension oculaire

Publications associées (24)

Neuroprotection in the Retina: From Preventing Inflammatory Cell Death to Promoting Vascular Stability in the Central Nervous System

Bokyoung Kim

Glaucoma is one of the leading causes of irreversible blindness worldwide. Glaucoma is defined clinically as the presence of optic nerve head (ONH) degeneration and progressive loss of retinal ganglion cells (RGCs). Intra-ocular pressure (IOP) has been con ...

EPFL2024

A new self-adjustable glaucoma valve

Nikolaos Stergiopoulos, Stéphane Bigler, Julien Maxime Gerber, Soroush Rafiei

Introduction: Glaucoma, the leading cause of irreversible blindness globally, affects more than 70 million people across the world. When initial treatments prove ineffective, especially for cases with high intraocular pressure (IOP), the preferred approach ...

Frontiers Media Sa2024

Intraocular Lens Refractive Index and Its Impact on External Surface Reflections

Georges Wagnières

PURPOSE: To determine and compare the origin of the external surface reflections produced by commonly used intraocular lenses (IOLs). ...

SLACK INC2021

Flexure-based mecano-optical multi-degree-of-freedom transducers dedicated to medical force sensing instruments

Sebastian Krzysztof Fifanski

This thesis develops novel multi-degrees-of-freedom flexure-based force sensors by exploiting white light interferometry. Fabry-Pérot interferometry measurement has nanometric accuracy which yields sub milli-Newton force sensing accuracy. Such force sensin ...

EPFL2020

EyeWatch Rescue of Refractory Hypotony After Baerveldt Drainage Device Implantation: Description of a New Technique

Nikolaos Stergiopoulos, André Mermoud, Adan Villamarin

The most effective way to control glaucoma is by lowering intraocular pressure (IOP) in order to prevent the progression of the disease. Glaucoma drainage devices (GDDs) are surgical option reserved for refractory cases and have been designed to address kn ...

LIPPINCOTT WILLIAMS & WILKINS2020

Comparison Between the eyeWatch Device and the Ahmed Valve in Refractory Glaucoma

Nikolaos Stergiopoulos, André Mermoud, Sylvain Roy, Adan Villamarin, Constantinos Stergiopulos, Stéphane Bigler

Purpose: To assess the efficacy and safety of a glaucoma procedure to control intraocular pressure (IOP) using the adjustable eyeWatch glaucoma drainage device compared with Ahmed glaucoma valve (AGV) in refractory glaucoma. Patients and Methods: Monocentr ...

LIPPINCOTT WILLIAMS & WILKINS2020

Outcome and Complications of Combined Modified Deep Sclerectomy and Trabeculectomy for Surgical Management of Glaucoma: A Pilot Study

André Mermoud, Sylvain Roy

Purpose: To report the outcome and complications of a combined surgical technique of modified deep sclerectomy and trabeculectomy (mDST) for glaucoma. Patients and Methods: Retrospective study of 44 eyes of 43 patients with open and closed angle glaucoma w ...

2020

Initial Clinical Results of the eyeWatch: a New Adjustable Glaucoma Drainage Device Used in Refractory Glaucoma Surgery

Nikolaos Stergiopoulos, André Mermoud, Sylvain Roy, Adan Villamarin, Constantinos Stergiopulos, Stéphane Bigler

Precis: In this study, we report clinical results after implantation of an adjustable glaucoma drainage device. The intraocular pressure (IOP) profile was efficiently controlled postoperatively as the resistance to aqueous humor outflow was finely adjusted ...

LIPPINCOTT WILLIAMS & WILKINS2019

Design and validation of a foldable and photovoltaic wide-field epiretinal prosthesis

Diego Ghezzi, Kevin Sivula, Marta Jole Ildelfonsa Airaghi Leccardi, Paola Vagni, Laura Ferlauto, Naïg Aurelia Ludmilla Chenais, Michele Bevilacqua

Retinal prostheses have been developed to fight blindness in people affected by outer retinal layer dystrophies. To date, few hundred patients have received a retinal implant. Inspired by intraocular lenses, we have designed a foldable and photovoltaic wid ...

Nature Research2018

Apparatus and methods for treating excess intraocular fluid

Nikolaos Stergiopoulos, Stéphane Bigler

An ocular drainage system is provided for treating diseases that produce elevated intraocular pressures, such as glaucoma, wherein the system includes an implantable device and an external control unit, the implantable device includes a non-invasively adju ...

2017

JNK Inhibition Reduced Retinal Ganglion Cell Death after Ischemia/Reperfusion In Vivo and after Hypoxia In Vitro

Tatiana Favez

Mitogen-activated protein kinases (MAPKs) are key regulators that have been linked to cell survival and death. Among the main classes of MAPKs, c-jun N-terminal kinase (JNK) has been shown to mediate cell stress responses associated with apoptosis. In Vitr ...

Springer Int Publishing Ag2016

Results of CO2 Laser-assisted Deep Sclerectomy as Compared With Conventional Deep Sclerectomy

André Mermoud, Sylvain Roy

Purpose: To evaluate the efficacy of CO2 laser-assisted sclerectomy surgery (CLASS) compared with classic nonpenetrating deep sclerectomy (NPDS) with implant in medically uncontrolled glaucoma patients. Materials and Methods: Patients who underwent primary ...

Lippincott, Williams & Wilkins2016

Eyewatch, an Innovative Adjustable GDD for the Treatment of Glaucoma - in Vivo Results

Nikolaos Stergiopoulos, André Mermoud, Sylvain Roy, Adan Villamarin, Stéphane Bigler

PURPOSE: To report the in vivo results of a continuously adjustable glaucoma drainage device (GDD) in glaucoma surgery with rabbits. METHODS: Under general anesthesia, the AGDD was implanted on 12 white New-Zealand rabbits for duration of 6 months. The adj ...

Springer2016

Molecular Analysis of NOTCH2 in Patients with Primary Open-Angle Glaucoma

Background and Purpose: Transgenic mice over-expressing Notch2 in the uvea exhibit a hyperplastic ciliary body leading to increased IOP and glaucoma. The aim of this study was to investigate the possible presence of NOTCH2 variants in patients with primary ...

Georg Thieme Verlag Kg2015

In Vivo Testing of a Novel Adjustable Glaucoma Drainage Device

Nikolaos Stergiopoulos, André Mermoud, Sylvain Roy, Adan Villamarin, Stéphane Bigler

PURPOSE. We report on the in vivo testing of a novel noninvasively adjustable glaucoma drainage device (AGDD), which features an adjustable outflow resistance, and assess the safety and efficiency of this implant. METHODS. Under general anesthesia, the AGD ...

Association for Research in Vision and Ophthalmology2014

A New Noninvasively Adjustable Glaucoma Drainage Device

Adan Villamarin

Glaucoma is an irreversible disease affecting the eye, leading to progressive loss of vision and eventually to total blindness. It is often related to high intraocular pressure (IOP), which results from increased outflow resistance to aqueous humor. The fi ...

EPFL2014

Notch Signaling in Pigment Cells and Generation of Mouse Models for Ocular Diseases

Bhushan Sarode

Cellular signaling mediated by Notch receptors results in coordinated regulation of cell growth, survival and differentiation. In melanocytes, Notch signaling is essential for the maintenance of melanocytes and the melanocyte stem cell population. Whereas, ...

EPFL2013

Dental Phenotype in Jalili Syndrome Due to a c.1312 dupC Homozygous Mutation in the CNNM4 Gene

Jalili syndrome denotes a recessively inherited combination of an eye disease (cone-rod dystrophy) and a dental disorder (amelogenesis imperfecta), which is caused by mutations in the CNNM4 gene. Whereas the ophthalmic consequences of these mutations have ...

Public Library of Science2013

Apparatus and methods for treating excess intraocular fluid

Nikolaos Stergiopoulos, Stéphane Bigler

An ocular drainage system is provided for treating diseases that produce elevated intraocular pressures, such as glaucoma, wherein the system includes an implantable device and an external control unit. The implantable device includes a non-invasively adju ...

2012

Data-Driven Visual Tracking in Retinal Microsurgery

Pascal Fua, Raphael Sznitman, Karim Ali

In the context of retinal microsurgery, visual tracking of instruments is a key component of robotics assistance. The difficulty of the task and major reason why most existing strategies fail on {\it in-vivo} image sequences lies in the fact that complex a ...

2012