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Concept

Cultured neuronal network

Publications associées (25)

Non-invasive neuromodulation of the right temporoparietal junction using theta-burst stimulation in functional neurological disorder

Serafeim Loukas

Background Disrupted sense of agency (SoA)-the sense of being the agent of one's own actions-has been demonstrated in patients with functional neurological disorder (FND), and a key area of the corresponding neuronal network is the right temporoparietal ju ...

Bmj Publishing Group2024

Modeling, fabrication and validation of 3D neural interfaces for peripheral nerves and brain organoids

Outman Akouissi

This thesis presents an extensive exploration of neuroelectronic interfaces, focusing on microfabrication, in silico modeling, and their applications in designing and fabricating devices for neural interfacing. The research encompasses both peripheral nerv ...

EPFL2024

Data Transformation in the Processing of Neuronal Signals: A Powerful Tool to Illuminate Informative Contents

Mohammad Ali Shaeri

Neuroscientists seek efficient solutions for deciphering the sophisticated unknowns of the brain. Effective development of complicated brain-related tools is the focal point of research in neuroscience and neurotechnology. Thanks to today's technological a ...

2023

Molecular reconstruction and simulation of the Neuron-Glia-Vasculature system

Polina Shichkova

The outstanding information processing capacity of the brain relies on numerous molecular mechanisms. It is an extremely energy-expensive function, which involves specialization and collaboration of different cell types. A common framework to study the com ...

EPFL2023

A 16-Channel 60µW Neural Synchrony Processor for Multi-Mode Phase-Locked Neurostimulation

Mahsa Shoaran, Uisub Shin, Cong Ding, Laxmeesha Somappa

Measuring neural oscillatory synchrony facilitates our understanding of complex brain networks and the underlying pathological states. Altering the cross-regional synchrony-as a measure of brain network connectivity-via phase-locked deep brain stimulation ...

IEEE2022

Fabrication and validation of an intraneural interface tailored for optic nerve stimulation

Eleonora Borda

Technological progress in materials science and microengineering along with new discoveries in neuroscience have contributed to restore lost or impaired sensory functions by closely interfacing with the nervous system. Electronic devices have begun to be i ...

EPFL2022

Transient Neurovascular Interface for Minimally Invasive Neural Recording and Stimulation

Diego Ghezzi, Philippe Reymond, Laura Ferlauto, Adele Fanelli, Elodie Geneviève Zollinger

Neural interfaces are used to mitigate the burden of traumatic injuries, neurodegenerative diseases, and mental disorders. However, the transient or permanent placement of an interface in close contact with the neural tissue requires invasive surgery, pote ...

Wiley2021

A Modular Workflow for Model Building, Analysis, and Parameter Estimation in Systems Biology and Neuroscience

Daniel Keller

Neuroscience incorporates knowledge from a range of scales, from single molecules to brain wide neural networks. Modeling is a valuable tool in understanding processes at a single scale or the interactions between two adjacent scales and researchers use a ...

HUMANA PRESS INC2022

Soft Printable Electrode Coating for Neural Interfaces

Stéphanie Lacour, Grégoire Courtine, Elvira Pirondini, Florian Dylan Fallegger, Quentin Barraud, Arnaud Bichat, Michael Shur

The mechanical mismatch between implantable interfaces and neural tissues may be reduced by employing soft polymeric materials. Here, we report on a simple strategy to prepare and pattern a soft electrode coating of neural interfacing devices based on a sc ...

2020

All-Printed Electrocorticography Array for In Vivo Neural Recordings

Diego Ghezzi, Laura Ferlauto, Eleonora Borda, Nenad Marjanovic, Fabian Michael Lütolf

Bioelectronic and neuroprosthetic interfaces rely on implanted microelectrode arrays (MEAs) to interact with the human body. Printing techniques, such as inkjet and screen printing, are attractive methods for the manufacturing of MEAs because they allow fl ...

2020

First Biopotential Recordings from a Liquid Crystal Optrode

Emilie Cornelia Maria Revol

One of the goals of the Neural Engineering System Design (NESD) program in the United States and of similar programs around the world is to develop an interface able to read from one million neurons in parallel. This is well beyond the capabilities of trad ...

SPIE-INT SOC OPTICAL ENGINEERING2019

Exploring the relative efficacy of motion artefact correction techniques for EEG data acquired during simultaneous fMRI

João Pedro Forjaco Jorge

Simultaneous EEG-fMRI allows multiparametric characterisation of brain function, in principle enabling a more complete understanding of brain responses; unfortunately the hostile MRI environment severely reduces EEG data quality. Simply eliminating data se ...

Wiley2019

Inferring subjective preferences on robot trajectories using EEG signals

Aude Billard, José del Rocio Millán Ruiz, Ricardo Andres Chavarriaga Lozano, Inaki Asier Iturrate Gil, Iason Batzianoulis, Fumiaki Iwane

Cognitive information has been exploited in non-invasive Brain Computer Interface (BCI) scenarios to provide autonomous external agents with additional information. In this context, Error-related potentials (ErrPs), temporal deflections in electroencephalo ...

IEEE2019

Microchannel-based technologies for nerve interfacing

Sandra Gribi

Biomedical technologies in neuroprosthetics are made to restore or replace functions from the nervous system, as well as alleviate pathological conditions. Peripheral nerve interfaces use neuromodulatory techniques to inhibit pain or depression, prevent ep ...

EPFL2019

Multilayer 3D electrodes for neural implants

Diego Ghezzi, Marta Jole Ildelfonsa Airaghi Leccardi, Paola Vagni

Objective. In many applications, multielectrode arrays employed as neural implants require a high density and a high number of electrodes to precisely record and stimulate the activity of the nervous system while preserving the overall size of the array as ...

2018

DCT Learning-Based Hardware Design for Neural Signal Acquisition Systems

Yusuf Leblebici, Volkan Cevher, Cosimo Aprile, Luca Baldassarre

This work presents an area and power efficient encoding system for wireless implantable devices capable of monitoring the electrical activity of the brain. Such devices are becoming an important tool for understanding, real-time monitoring, and potentially ...

2017

Flexible Optoelectric Neural Interface Integrated Wire-Bonding mu LEDs and Microelectrocorticography for Optogenetics

Xiaoyang Kang

As an advanced brain-computer interface, the flexible surface electrodearrayhas been used for spatiotemporal localization of neural interactions by recording electrocorticography (ECoG) signals over brain cortical areas. Compared with the electrical stimul ...

Ieee-Inst Electrical Electronics Engineers Inc2017

Toward precision medicine: tailoring interventional strategies based on noninvasive brain stimulation for motor recovery after stroke

Friedhelm Christoph Hummel, Philipp Johannes Koch

Purpose of reviewTo support the recovery of disability and the reduced functional capacity influencing the independence of daily life after focal brain lesions like stroke, the application of noninvasive brain stimulation (NIBS) by repetitive transcranial ...

Lippincott Williams & Wilkins2017

Bidirectional Limb Neuro-Prosthesis

Silvestro Micera, Marco Capogrosso, Stanisa Raspopovic, Francesco Maria Petrini, Marco Bonizzato

Integrated closed-loop real-time limb neuro-prosthetic system comprising an artificial limb, a microprocessor, sensors, a signal conditioner, a stimulator, at least one EMG electrode and at least one sensory feedback electrode, characterized by the fact th ...

2016

Local field potentials in primate motor cortex encode grasp kinetic parameters

Tomislav Milekovic

Reach and grasp kinematics are known to be encoded in the spiking activity of neuronal ensembles and in local field potentials (LFPs) recorded from primate motor cortex during movement planning and execution. However, little is known, especially in LFPs, a ...

Elsevier2015