Mediaspace scheduled maintenance: Aug 25, 2026 07:00 - 12:00 AM. During this time, videos will be temporarily unavailable. Check status updates.

Concept

Souche (biologie)

Publications associées (19)

Bactericidal effect of tetracycline in E. coli strain ED1a may be associated with ribosome dysfunction

Camille Véronique Bernadette Goemans, Christian Eugen Zimmerli

Ribosomes translate the genetic code into proteins. Recent technical advances have facilitated in situ structural analyses of ribosome functional states inside eukaryotic cells and the minimal bacterium Mycoplasma. However, such analyses of Gram-negative b ...

Nature Research2024

Engineering extracellular electron transfer for enhanced energy harvesting in microbial electrochemical devices

Mohammed Mouhib

Microorganisms known as exoelectrogens evolved the ability of transporting electrons across insulating biological membranes. In a physiological context, this enables respiration on extracellular electron acceptors and electron transfer to other organisms. ...

EPFL2023

Sulfurospirillum diekertiae sp. nov., a tetrachloroethene-respiring bacterium isolated from contaminated soil

Christof Holliger, Julien Maillard

Two anaerobic, tetrachloroethene- (PCE-) respiring bacterial isolates, designated strain ACSDCE T and strain ACSTCE, were characterized using a polyphasic approach. Cells were Gram-stain-negative, motile, non-spore-forming and shared a vibrioid- to spirill ...

Society for General Microbiology2023

Genotype-Dependent Kinetics of Enterovirus Inactivation by Free Chlorine and Ultraviolet (UV) Irradiation

Tamar Kohn, Shotaro Torii, Marie-Hélène Chantal Corre

Inactivation kinetics of enterovirus by disinfection is often studied using a single laboratory strain of a given genotype. Environmental variants of enterovirus are genetically distinct from the corresponding laboratory strain, yet it is poorly understood ...

2022

Interbacterial competition and anti‐predatory behavior of environmental Vibrio cholerae strains

Melanie Blokesch, Natalia Carolina Drebes Dorr

Vibrio cholerae isolates responsible for cholera pandemics represent only a small portion of the diverse strains belonging to this species. Indeed, most V. cholerae are encountered in aquatic environments. To better understand the emergence of pandemic lin ...

2020

Variability in Disinfection Resistance between Currently Circulating Enterovirus B Serotypes and Strains

Tamar Kohn, Simon Meister, Matthew Eric Verbyla

The susceptibility of waterborne viruses to disinfection is known to vary between viruses and even between closely related strains, yet the extent of this variation is not known. Here, different enteroviruses (six strains of coxsackievirus B5, two strains ...

2018

High-throughput microfluidic platforms applied to immunoassay-based diagnostics and environmental monitoring

Francesca Volpetti

The research presented in this thesis is motivated by the aim to employ microfluidic devices for high-throughput analysis. Two applications, in particular, have been explored: diagnostics and environmental sensing. Miniaturization and multiplexing of labor ...

EPFL2017

Molecular phylogeny suggests transfer of Hemidiscus into Actinocyclus (Coscinodiscales, Coscinodiscophyceae)

Lu Wang

Hemidiscus cuneiformis, type of the family Hemidiscaceae, is a diatom with a distinctive semi-circular shape in valve view. A strain of H. cuneiformis was established from the coastal region of the tropical southwestern Atlantic Ocean off Brazil. Cells of ...

Taylor & Francis Ltd2017

Plasmonic nanohole array biosensor for label-free and real-time analysis of live cell secretion

Hatice Altug, Filiz Yesilköy, Alexander Belushkin, Xiaokang Li, Maria Soler Aznar

Cell secretion dynamics plays a central role in physiological and disease processes. Due to its various temporal profiles, it is essential to implement a precise detection scheme for continuous monitoring of secretion in real time. The current fluorescent ...

Royal Society of Chemistry2017

Miniaturized Dielectric Elastomer Actuator for Mechanical Stimulation of Monolayer Cell Cultures

Alexandre Poulin

This thesis advances the field of dielectric elastomer actuators (DEAs) through the development of device designs, fabrication processes, strain characterization technique and modelling tool. It provides the first demonstration that DEAs can be interfaced ...

EPFL2016

A Balance between Inhibitor Binding and Substrate Processing Confers Influenza Drug Resistance

Jeffrey David Jensen, Claudia Bank

The therapeutic benefits of the neuraminidase (NA) inhibitor oseltamivir are dampened by the emergence of drug resistance mutations in influenza A virus (IAV). To investigate the mechanistic features that underlie resistance, we developed an approach to qu ...

Academic Press Ltd- Elsevier Science Ltd2016

Circulation of a Quorum-Sensing-Impaired Variant of Vibrio cholerae Strain C6706 Masks Important Phenotypes

Melanie Blokesch, Sandrine Stutzmann

Vibrio cholerae, the causative agent of cholera, is a model organism for studying virulence regulation, biofilm formation, horizontal gene transfer, and the cell-to-cell communication known as quorum sensing (QS). As in any research field, discrepancies be ...

Amer Soc Microbiology2016

Quantitative single-cell analysis of S. cerevisiae using a microfluidic live-cell imaging platform

Johannes Becker

Genome-wide manipulations and measurements have made huge progress over the last decades. In Saccharomyces cerevisiae, a well-studied eukaryotic model organism, homologous recombination allows for systematic deletion or alteration of a majority of its gene ...

EPFL2015

Evaluation of the efficiency of the photo Fenton disinfection of natural drinking water source during the rainy season in the Sahelian region

César Pulgarin, Juliette Ndounla

The photo-disinfection of water from two different wells (W1, pH: 4.6–5.1 ± 0.02) and (W2 pH: 5.6–5.7 ± 0.02) was carried out during the rainy season at Ouagadougou–Burkina Faso, West Africa. The weather variation during the rainy season significantly affe ...

Elsevier2014

Metabolomics of hexachlorocyclohexane (HCH) transformation: ratio of LinA to LinB determines metabolic fate of HCH isomers

Christof Holliger

Although the production and use of technical hexachlorocyclohexane (HCH) and lindane (the purified insecticidal isomer -HCH) are prohibited in most countries, residual concentrations still constitute an immense environmental burden. Many studies describe t ...

Wiley-Blackwell2013

Biothermodynamics of live cells: a tool for biotechnology and biochemical engineering

Urs von Stockar

The aim of this contribution is to review the application of thermodynamics to live cultures of microbial and other cells and to explore to what extent this may be put to practical use. A major focus is on energy dissipation effects in industrially relevan ...

De Gruyter2010

FluReF, an automated flu virus reassortment finder based on phylogenetic trees

Bernard Moret, Alisa Yurovsky

Background: Reassortments are events in the evolution of the genome of influenza (flu), whereby segments of the genome are exchanged between different strains. As reassortments have been implicated in major human pandemics of the last century, their identi ...

IEEE Press2010

Nanoscale strain characterisation for ultimate CMOS and beyond

Mihai Adrian Ionescu, Kirsten Emilie Moselund

Strain engineering is used to maintain Moore's Law in scaled CMOS devices and as a technology booster for More-than-Moore devices in the nanoelectronics era. Strain is crucial because of its ability to increase electron and hole mobilities in Si. However, ...

Elsevier2008

Haloalkane Dehalogenase LinB is responsible for β- and δ-hexachlorocyclohexane transoformation in sphingobium indicum B90A

Christof Holliger

Incubation of resting cells of Sphingobium indicum B90A, Sphingobium japonicum UT26, and Sphingobium francense Sp+ showed that they were able to transform ß- and -hexachlorocyclohexane (ß- and -HCH, respectively), the most recalcitrant hexachlorocyclohexan ...

2006