Bruno Emanuel Ferreira De Sousa CorreiaThroughout my PhD and postdoctoral studies I was trained in world-renowned laboratories and institutions in the United States of America (University of Washington and The Scripps Research Institute). Very early in my scientific career I found out my fascination about protein structure and function. My PhD studies evolved in the direction of immunogen design and vaccine engineering which sparked my interest in the many needs and opportunities in vaccinology and translational research. My efforts resulted in an enlightening piece of work where for the first time, computationally designed immunogens elicited potent neutralizing antibodies. During my postdoctoral studies I joined a chemical biology laboratory at the Scripps Research Institute. In this stage I developed novel chemoproteomics methods for the identification of protein-small molecule interaction sites in complex proteomes. In March 2015, I joined the École Polytechnique Fédérale de Lausanne (EPFL) – Switzerland as a tenure track assistant professor. The focus of my research group is to develop computational tools for protein design with particular emphasis in applying these strategies to immunoengineering (e.g. vaccine and cancer immunotherapy). The activities in my laboratory focus on computational design methods development and experimental characterization of the designed proteins. Our laboratory has been awarded with 2 prestigious research grants from the European Research Council. Lastly, I have been awarded the prize for best teacher of Life sciences in 2019.
Christian HeinisEnseignement et PhD Doctorant·es actuel·les Thomas Julien Denis Emel, Alessandro Scapozza, Nathan Moïse De Sadeleer, Florian Handel, Hugo André Clerc, Frédéric Brantschen, Grégoire Menoud, Ines Michrafy, Jonathan Schmitt, Laura Elena Massaad A dirigé les thèses EPFL de Jeremy Touati, Shiyu Chen, Sophie Venet-Bonnot, Lisa Pollaro, Inmaculada Rentero Rebollo, Philippe Diderich, Charlotte Urech-Varenne, Silvia Bellotto, Davide Bertoldo, Alessandro Zorzi, Camille Villequey, Jonas Alfred Karl Wilbs, Grigory Ka
Stewart ColeProfessor Stewart Cole is an international authority in bacterial molecular-genetics and genomics. He has made outstanding contributions in several fields including: bacterial anaerobic electron transport; genome analysis of retroviruses and papillomaviruses; antibiotic resistance mechanisms; and the molecular microbiology of toxigenic clostridia. His studies on isoniazid and multidrug resistance in Mycobacterium tuberculosis, together with his pioneering work on the pathogenicity, evolution and genomics of the tubercle and leprosy bacilli, have made him an undisputed leader in the field of mycobacterial research. The findings of his research are of direct relevance to public health and disease-control in both the developing world and the industrialised nations. He has published over 250 scientific papers and review articles, and holds many patents.
Berend SmitEnseignement et PhD Doctorant·es actuel·les Anastasia Blokhina, Raluca-Ana Kessler, Seyed Amirmohammad Elahi, Juliette Veronique Schleicher, Yutao Li, Xin Jin, Sara Bassetta, Beatriz Bueno Mouriño A dirigé les thèses EPFL de Samantha Lynn Anderson, Daniele Ongari, Andrzej Gladysiak, Seyedmohamad Moosavi, Arunraj Chidambaram, Bardiya Valizadeh, Stavroula Kampouri, Fatmah Ebrahim, Fatma Pelin Uran, Andres Adolfo Ortega Guerrero, Kevin Maik Jablonka, Elias Moubarak, Sauradeep Majumdar, Miriam Jasmin Pougin,
Harm-Anton KlokExpertise
Polymer design at nanoscaleBiologically-inspired polymers
Enseignement et PhD Doctorant·es actuel·les Nicola Carrara, Berlind Vosberg, Maja Lopandic, Sneha Cheriyamparambil, Thanh Thi Hà Lê, Suqiu Jiang, Adam William Woodhouse, Kunita Numabe A dirigé les thèses EPFL de Stefano Tugulu, Markus Scholl, Harald Nuhn, Nadja Franz, Raphaël Barbey, Bojana Portmann, Maarten Danial, Dusko Paripovic, Sanhao Ji, Nicolas Bertrand Schüwer, Zuzana Kadlecova, Görçin Görkem Sahin Kurtuldu, Caroline Sugnaux, Sole
Marc ChambonEnseignement et PhD Cours Methods: from disease models to therapy BIOENG-518 Ce cours décrira les méthodes qui sont à la base des approches translationnelles depuis la génération et la caractérisation des modèles des maladies jusqu'aux applications thérapeutiques. Les bases théoriques seront complétées par des rotations pratiques dans les plateformes technologiques.
Patrick Daniel BarthProfessor Patrick Barth is Associate Professor at EPFL and Adjunct Associate Professor at Baylor College of Medicine, Houston, TX, USA. He received training in Physics, Chemistry and Biology (University of Paris, ENS) in France and performed his PhD at the Commissiariat a l'Energie Atomique in Saclay, France on structure/function studies of membrane proteins (photosystem I) using biochemical and biophysical experimental techniques. He carried out postdoctoral studies at University of California at Berkeley with Tom Alber on computational development for calculating protein electrostatics and designing de novo selective peptide inhibitors of cellular protein interactions. He then went to the University of Washington as a postdoctoral fellow and instructor in David Baker's laboratory to develop computational techniques in the software Rosetta for predicting and designing membrane protein structures. He started his independent career and received tenure at Baylor College of Medicine. He will continue at EPFL to marry computation and experiment for understanding the molecular determinants of signal transduction, as well as modeling and designing membrane proteins with novel functions for various synthetic biology and therapeutic applications.
Paolo De Los RiosEnseignement et PhD Doctorant·es actuel·les María Li López Bautista, Subhasis Dehury, Lisa Gennai A dirigé les thèses EPFL de Giovanni Salvi, Thomas Petermann, David Gfeller, Cécile Caretta Cartozo, David Morton de Lachapelle, Carlo Maffi, Lucio Floretta, Salvatore Assenza, Duccio Malinverni, Alberto Stefano Sassi, Andrea Martini, Solange Flatt, Adélaïde Alice Mohr, Shiling Liang, Alexandra Shelest, Davide Cois A co-dirigé les thèses EPFL de Lorenzo Talamanca Cours EDCB seminar series BIOENG-606
Luc PatinyExpertise
Cheminformatics, Data management, Data processing, Javascript developmentLast updated on April 16, 2023.
GitHub
https://github.com/lpatiny
Enseignement et PhD Cours Analyse structurale (pour SFU) UNIL-129 Acquisition des notions fondamentales liées à l'identification de la structure de petites molécules organiques au moyen des techniques de spectrométrie de masse, spectroscopie infra-rouge et résonance magnétique nucléaire. Basic and advanced NMR - Level 1 A (EPFL) CH-60 Florian Frédéric Vincent BreiderTravail en cours
My current work involves: (I) elucidating the formation mechanisms of carcinogenic/mutagenic N-nitrosamines in aquatic systems under varying environmental conditions, (II) developing new analytical tools to detect and quantify N-nitroso compounds in water and biological fluids, and (III) elucidating the role of disinfection agents in the prevalence of antibiotic resistant bacteria in wastewater
RechercheConferences Breider F., von Gunten U., (2017) Novel method for the quantification of th
Benoît Jean Dominique FerrariBiologiste et biochimiste de formation, Benoît J.D. Ferrari a obtenu son diplôme de doctorat en Ecotoxicologie à lUniversité de Lorraine (Metz, France) en 2000 en travaillant sur le développement dune approche dévaluation du danger écotoxique des déchets solides utilisant une batterie de bioessais dans le cadre dun projet interdisciplinaire suivi par lAgence de lEnvironnement et de la Maîtrise de lEnergie (ADEME). Après avoir passé presque 7 années à Irstea (anciennement Cemagref) à Lyon en France (périodes 2000-2002 et 2008-2013) et avoir occupé un poste de Maitre-assistant à lInstitut F.A. Forel à Genève (2002-2008), il a acquis au travers des projets franco-suisses et européens quil a (co-)pilotés une expérience forte dans le domaine de lécotoxicologie et dans les approches pluridisciplinaires. En Octobre 2013, il rejoint le Centre Suisse dEcotoxicologie Appliquée (Centre Ecotox Eawag/EPFL) en tant que responsable du groupe Sol et Sédiment. Sintéressant à létude de lécodynamique des contaminants et leurs effets sur lécophysiologie des organismes, ses compétences et ses thématiques de recherche appliquée couvrent aujourdhui :
Le développement dindicateurs écotoxicologiques dexposition et deffets pour évaluer le stresse chimique
Lintégration des indicateurs écotoxicologiques dans des approches de laboratoire et de terrain pour le diagnostic de la qualité des écosystèmes
Le développement de bioessais adaptés pour le biomonitoring actif
Le transfert de compétence vers la sphère opérationnelle (formation).
