Otorhinolaryngologie

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Towards the end of the second trimester of gestation, a human fetus is able to register environmental sounds. This in utero auditory experience is characterized by comprising strongly low-pass-filtered versions of sounds from the external world. Here, we p ...

The auditory brainstem implant (ABI) is an auditory neuroprosthesis that provides hearing to deaf patients by electrically stimulating the cochlear nucleus (CN) of the brainstem. Whether such stimulation activates one or the other of the CN's two major sub ...

Next-generation sequencing (NGS) is an essential technology for DNA identification in genomic research. DNA fragmentation is a critical step for NGS and doing this on-chip is of great interest for future integrated genomic solutions. Here we demonstrate fa ...

Non-Syndromic Hereditary Hearing Loss (NSHHL) is a genetically heterogeneous sensory disorder with about 120 genes already associated. Through exome sequencing (ES) and data aggregation, we identified a family with six affected individuals and one unrelate ...

Vestibular schwannomas (VS) are slow-growing intracranial extraaxial benign tumors, developing from the vestibular part of the eight cranial nerves. Stereotactic radiosurgery (SRS) has now a long-term scientific track record as first intention treatment fo ...

Surgeons generally assess the mobility of the ossicle chain by manual palpation using rigid elongated hooks inserted through the ear canal. As the applied forces are in the range of a few grams equivalent force, the measurement remains subjective and its r ...

There is growing evidence showing that the representation of the human “self” recruits special systems across different functions and modalities. Compared to self-face and self-body representations, few studies have investigated neural underpinnings specif ...

Sensorimotor conflicts are known to alter the perception of accompanying sensory signals, and deficits in sensory attenuation have been observed in schizophrenia. In the auditory domain, self-generated tones or voices (compared to tones or voices presented ...

Future high-field accelerator magnets foresee the extensive use of Nb3Sn, more expensive than the Nb-Ti of LHC. For projects involving the series production of magnets, conductor grading is mandatory in order to reduce the cost. To allow grading ...

Viral delivery of exogenous coding sequences into the inner ear has the potential for therapeutic benefit for patients suffering genetic or acquired hearing loss. To devise improved strategies for viral delivery, we investigated two injection techniques, r ...

Objective:The cochlear nucleus (CN) is the target of the auditory brainstem implant (ABI). Most ABI candidates have Neurofibromatosis Type 2 (NF2) and distorted brainstem anatomy from bilateral vestibular schwannomas. The CN is difficult to characterize as ...

Inspired by the prominent theory suggesting that auditory-verbal hallucinations (AVH) - the sensation of hearing voices without present speakers - arise as misattribution of inner speech towards external agents, my thesis revolved around self-voice percept ...

Otorhinolaryngologie

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Prenatal auditory experience and its sequelae

Comparison of Responses to DCN vs. VCN Stimulation in a Mouse Model of the Auditory Brainstem Implant (ABI)

Polydimethylsiloxane microstructure-induced acoustic streaming for enhanced ultrasonic DNA fragmentation on a microfluidic chip

Variants in USP48 encoding ubiquitin hydrolase are associated with autosomal dominant non-syndromic hereditary hearing loss

Repeat stereotactic radiosurgery for progressive vestibular schwannomas after previous radiosurgery: a systematic review and meta-analysis

Design and modelling of a compliant constant-force surgical tool for objective assessment of ossicular chain mobility

EEG Spatiotemporal Patterns Underlying Self-other Voice Discrimination

Sensorimotor conflicts induce somatic passivity and louden quiet voices in healthy listeners

Progress on Tests on Splices Between Nb3Sn Rutherford Cables for Graded High-Field Accelerator Magnets

Efficient viral transduction in mouse inner ear hair cells with utricle injection and AAV9-PHP.B

Human Cochlear Nucleus on 7 Tesla Diffusion Tensor Imaging: Insights Into Micro-anatomy and Function for Auditory Brainstem Implant Surgery

Dissecting self-voice perception: From bone conduction to robotically-induced self-other voice misattribution in healthy listeners