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We show aging of Glauber-type dynamics on the random energy model, inthe sense that we obtain the annealed scaling limits of the clock process and of theage process. The latter encodes the Gibbs weight of the configuration occupied by thedynamics. Both lim ...

The developed world is aging faster than ever before. Even in the absence of neurodegenerative disease, aging affects all kinds of human functions including perception and cognition. In most perceptual studies, one paradigm is tested and it is usually foun ...

Studies of the real-time dynamics of embryonic development require a gentle embryo handling method, the possibility of long-term live imaging during the complete embryogenesis, as well as of parallelization providing a population's statistics, while keepin ...

Degeneration of specific neuronal populations and progressive nervous system dysfunction characterize neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. These findings are also reported in inherited diseases such as phenylke ...

Rapid remodeling of the actin cytoskeleton in the pre- and/or post-synaptic compartments is responsible for the regulation of neuronal plasticity, which is an important process for learning and memory. Cofilin1 plays an essential role in these processes an ...

As centenarians well represent the model of healthy aging, there are many important implications in revealing the underlying molecular mechanisms behind such successful aging. By combining NMR metabonomics and shot-gun lipidomics in serum we analyzed metab ...

Increased expression of α-synuclein and point mutations in its amino acid sequence play a causative role in familial forms of Parkinson's disease (PD). In addition, circumstances affecting the level of α-synuclein expression significantly increase the risk ...

The dielectric response of hard (Fe-doped) and soft (Nb-doped) rhombohedral Pb(Zr0.58Ti0.42)1−xMexO3 (Me=Fe or Nb) ceramics was studied at subswitching conditions over a wide range of temperatures (50– 450 °C) and frequencies (10 mHz to 10 kHz). The result ...

An analytical model is presented for the analysis of constant flux tests conducted in a phreatic aquifer having a partially penetrating well with a finite thickness skin. The solution is derived in the Laplace transform domain for the drawdown in the pumpi ...

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Aging of asymmetric dynamics on the random energy model

The effects of aging on perception and cognition

Aging and perception

An automated microfluidic platform for C. elegans embryo arraying, phenotyping, and long-term live imaging

Metabolic Disturbances in Diseases with Neurological Involvement

Inactivation of brain Cofilin-1 by age, Alzheimer's disease and gamma-secretase

Serum profiling of healthy aging identifies phospho- and sphingolipid species as markers of human longevity

Role of the FoxO3a Transcription Factor in alpha-synuclein Induced Neurodegeneration

Charge migration in Pb(Zr,Ti)O3 ceramics and its relation to ageing, hardening and softening

Effect of wellbore storage and finite thickness skin on flow to a partially penetrating well in a phreatic aquifer