Publication

c-MAF coordinates enterocyte zonation and nutrient uptake transcriptional programs

Matthias Lütolf, Jakob Josef Langer
2022
Journal Articles

Abstract

c-MAF, highly expressed in villus small intestinal enterocytes, coordinates transcriptional programs for nutrient absorption. Enterocyte-specific c-MAF inactivation impairs dietary lipid handling but also leads to tuft cell expansion and adaptive gut lengthening, revealing crosstalk between enterocytes and tuft cells during intestinal adaptation.

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c-MAF coordinates enterocyte zonation and nutrient uptake transcriptional programs

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