Common mechanistic features among metallo-β-lactamases: a computational study of Aeromonas hydrophila CphA enzyme

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Fast spreading antimicrobial resistance (AMR) is an emerging major public health issue. New therapeutic and diagnostic paradigms must be implemented to counteract this evolution. In this respect, fast antimicrobial susceptibility testing (AST) plays an imp ...

Uropathogenic Escherichia coli (UPEC) proliferate within superficial bladder umbrella cells to form intracellular bacterial communities (IBCs) during early stages of urinary tract infections. However, the dynamic responses of IBCs to host stresses and anti ...

Cellular respiration is a fundamental feature of metabolic activity and oxygen consumption can be considered as a reliable indicator of bacterial aerobic respiration, including for facultative anaerobic bacteria like E. coli. Addressing the emerging global ...

The metabolic capabilities of the species and the local environment shape the microbial interactions in a community either through the exchange of metabolic products or the competition for the resources. Cells are often arranged in close proximity to each ...

Urinary tract infections (UTIs) are amongst the most common bacterial infections and are the second-most frequent reason for antibiotic prescriptions. Moreover, in about 25% of all treated cases, recurrence of infection occurs. Uropathogenic Escherichia co ...

To reveal rare phenotypes in bacterial populations, conventional microbiology tools should be advanced to generate rapid, quantitative, accurate, and high-throughput data. The main drawbacks of widely used traditional methods for antibiotic studies include ...

Disinfection agents have been present in our daily lives for several decades in detergents or in personal care products, where their role is to prevent the spread of pathogenic microor-ganisms. One of the largest class of disinfection agents is quaternary ...

Common mechanistic features among metallo-β-lactamases: a computational study of Aeromonas hydrophila CphA enzyme

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Microfluidic Platforms for the Study of Bacterial Metabolism and Antimicrobial Susceptibility Testing

Dynamic persistence of UPEC intracellular bacterial communities in a human bladder-chip model of urinary tract infection

Antimicrobial susceptibility testing by measuring bacterial oxygen consumption on an integrated platform

Spatio-temporal modeling of the crowding conditions and metabolic variability in microbial communities

Microtissue models for studying the dynamics of host-pathogen interactions in the urinary bladder

Revealing Antibiotic Tolerance of the Mycobacterium smegmatis Xanthine/Uracil Permease Mutant Using Microfluidics and Single-Cell Analysis

Presence of sub-inhibitory concentrations of quaternary ammonium compounds in water: effects on bacteria and their inactivation by ozone and monochloramine